Clinical trials: Orthopedic Procedures
Orthopedic Procedures, Methicillin-resistant Staphylococcus Aureus
Treatment of Patients Colonized With Methicillin-Resistant Staphylococcus Aureus Prior to Bone and Joint Surgery
The investigators anticipate that utilization of retapamulin preoperatively will eliminate MRSA colonization among patients who are colonized in their nares.
- Trial name
- TOPS-MRSA (NCT00903279)
- Testing
- Altabax (retapamulin)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bay Pines VA Healthcare System
Pain
Brief Mindfulness Intervention for Orthopedic Patients: Mechanistic Investigation
This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The analgesic effects of a 4-minute audio-recorded mindfulness intervention for orthopedic patients will be investigated relative to a 4-minute…
- Trial name
- NCT06171009
- Testing
- Pain Coping Information, Mindful Pain Management
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Florida State University
Arthropathy of Hip, Arthropathy of Knee
Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash
Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block.
- Trial name
- NCT02619409
- Testing
- Bupivacaine Only, EPI25, EPI50 group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Automobile Driving With an Aircast Walker, Automobile Driving With a Walking Cast
Effects of Right Lower Limb Orthopedic Immobilization on Braking Function
Research on the implications of orthopedic injury and surgery on automobile driving ability has been limited. Only a handful of orthopedic issues have been studied to date, especially the safe postoperative resumption of driving.
- Trial name
- NCT01171287
- Testing
- Driving with an Aircast Walker, Driving with a walking cast, Driving with a running shoe
- Where
- 2 sites in Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Femur Fracture
Pediatric Femur Research Project
Current treatment protocol for pediatric femoral shaft fractures is immediate spica casting for patients 6 years and younger and for patients over 6 years and older is percutaneous or open placement of titanium elastic…
- Trial name
- NCT00943332
- Testing
- femur fracture repair
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Orthopaedic Trauma Infections
BBOT: Bacterial Burden in Ortho Trauma Procedures
The purpose of this research project is to improve understanding of the potential role of highly sensitive bacterial tests in diagnosing infected non-healing fractures compared to the current standard of care, microbiologic…
- Trial name
- NCT03126448
- Testing
- Highly Sensitive Assays
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Anxiety, Pain
Virtual Reality Pediatric Orthopaedic Outpatient Procedures
The main objective of the study is to evaluate the use of Virtual Reality (VR) in managing pain and anxiety levels during common pediatric orthopaedic outpatient procedures which include: cast application, cast removal, hardware…
- Trial name
- VPRO (NCT03784352)
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Cleft Lip and Palate
Two Methods of Lip Taping as a Presurgical Orthopedic Appliance
A randomized clinical trial to compare the effectiveness of two methods of lip taping as a presurgical orthopedic appliances on maxillary arch dimensions in infants with bilateral cleft lip and palate.
- Trial name
- NCT05796336
- Testing
- Lip taping
- Where
- Iraq
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Hip Fracture
A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for…
- Trial name
- NCT01547468
- Testing
- Femoral Nerve Catheterization, Intravenous Opioids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leslie Thomas
Range of Motion
Stability Effects After Heel Cups Orthopedics Treatment in Different BMI
Actual research relates Body mass Index (BMI) with postural changes in children and musculoskeletal disorders during growing period.
- Trial name
- NCT06510933
- Testing
- Heel cups in different BMI index and its correlation to physical activity in children
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Pain, Postoperative, Orthopedic Procedures
A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain
The purpose of this small study was to investigate the safety and effectiveness of OROS hydromorphone HCI for the treatment of short-term, moderate to severe postoperative pain following total knee replacement surgery.
- Conditions
- Pain, Postoperative, Orthopedic Procedures, Analgesia
- Trial name
- NCT00411307
- Testing
- OROS hydromorphone HCI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Obesity, Knee Osteoarthritis
BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients
The goal of this clinical trial is to prospectively assess the efficacy of the BLOOM program, a comprehensive weight loss dietary and lifestyle program, in a population of patients living with obesity and awaiting hip or knee…
- Conditions
- Obesity, Knee Osteoarthritis, Hip Osteoarthritis, Arthroplasty Complications
- Trial name
- NCT06103552
- Testing
- Building Lifestyle Options for Orthopedic Mobility (BLOOM)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Fracture of Lower Limb
Comparing Heavy Levobupivacaine With Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine.
The purpose of this study is to compare the non-inferiority between Heavy Levobupivacaine with Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine During Spinal Anesthesia for Orthopedic Procedures in the Lower Limbs.
- Trial name
- NCT01308047
- Testing
- Bupivacaine
- Where
- 2 sites in Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Prophylaxis of Deep Vein Thrombosis
Study Evaluation of Recombinant Hirudin in Prophylaxis of Post-Operative Deep Vein Thrombosis
This study aims to evaluate the efficacy and safety of r-Hirudin RB variant 15 mg in DVT prophylaxis post major orthopedic operations
- Trial name
- Thromb-001 (NCT05847205)
- Testing
- r-Hirudin
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- MinaPharm Pharmaceuticals
Chronic Low Back Pain, Physiotherapy
Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 2)
The purpose of this study is to investigate the effect on QoL, PI and the AROM° in patients with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain, Physiotherapy, Quality of Life, Range of Motion
- Trial name
- CLBP (NCT03309540)
- Testing
- Physioterapy intervention
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Fracture; Complication Orthopedic Procedure
The Effect of Using a Kaleidoscope on Fear and Pain in Children
The research was conducted in randomized controlled experimental type between May 2022 and December2023. The universe of the research consisted of children and their parents who were diagnosed with a fracture, applied to the…
- Trial name
- NCT06261112
- Testing
- kaleidescope
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mihriban Culha
Orthopedic
A Comparison of Ultrasound and Nerve Stimulator Techniques for Nerve Localization in Regional Anesthesia
The primary objective of this study is to compare ultrasound versus nerve stimulator techniques for nerve localization when performing peripheral nerve blocks.
- Trial name
- NCT01221415
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Trigger Thumb
Study of Open and Percutaneous Release of Acquired Trigger Thumb
Trigger finger, also known as trigger digit or stenosing tenovaginitis, is caused by a size mismatch between the flexor tendon and the A1 pulley, which is generally characterized by pain, swelling, the limitation of finger range…
- Trial name
- NCT03679793
- Testing
- Open Release Group, Percutaneous Release Group
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Orthopedic Procedure
Implementation of Fast-track Surgery Program for Total Hip and Knee Replacement and the Evaluation of the Risks and Benefits for the Patient
Implementation of Fast-track surgery for total hip replacement and total knee replacement and evaluation of the risks and benefits for the patients.
- Trial name
- NCT03028779
- Testing
- Fast-track Total Hip and knee arthroplasty
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Hemodynamic Monitoring, Orthopedic Procedures
Hemodynamic and Cerebral Effects Evaluation in Anesthesia
Recently, there has been an increase in the popularity of minimally invasive surgical techniques, including arthroscopic surgeries for shoulder procedures.
- Trial name
- NCT05445037
- Testing
- hemodynamic continuous monitoring, Standard Monitoring
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo