Clinical trials: Orthopedic Surgeries
Pain Management, Anaesthesia Complication
Efficacy of Variable Volume Truncal Blocks in Upper Limb Orthopedic Surgery
aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist…
- Trial name
- NCT06664203
- Testing
- Selective turuncus block with 25 ml bupivacain, Selective turuncus block with 15 ml bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Respiratory Aspiration, Hyperglycemia
Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery
Before surgery, patients are asked to fast so the stomach is empty and stomach contents cannot enter the lungs during anesthesia. Long fasting is uncomfortable and can raise blood sugar and stress responses in older adults.
- Conditions
- Respiratory Aspiration, Hyperglycemia, Inflammation
- Trial name
- CHO-GERIGAS (NCT07872683)
- Testing
- Maltodextrin carbohydrate drink, Sugar water
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University
Post Spinal Anesthesia Shivering
The Effect of Different Doses of Dexamethasone on Post Spinal Anesthesia Shivering
The precise etiology of post-spinal anesthesia shivering (PSAS) is not fully understood. The incidence ranges between 20 to 80%.
- Trial name
- NCT06999070
- Testing
- Dexamethasone 0.1mg/kg, Dexamethasone 0.3mg/kg
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ischemia, Blood Circulation Disorder
New Method for Real-time Detection of Tissue Ischemia
This is a prospective, single arm, open, single centre clinical investigation designed to examine the feasibility and safety of the IscAlert™ device in patients scheduled for limb (arm/leg) surgery with tourniquet.
- Conditions
- Ischemia, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- ISCALERT (NCT04893473)
- Testing
- IscAlert
- Where
- Norway
- Sponsor
- Oslo University Hospital
Diabetes Mellitus, Surgical Procedure, Unspecified
DRIVE - Perioperative Period
This study will investigate if the HbA1c result before surgery which assesses glucose control over the longer term, can accurately predict what happens to the glucose levels and glucose profile following surgery.
- Trial name
- DRIVE-Periop (NCT04033705)
- Testing
- Freestyle Libre Pro glucose sensor
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Osteoporosis, With or Without Treatment, Bisphosphonate Treatment
Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
Bisphosphonates are drugs that prevent bone loss by blocking the activity of cells that normally resorb bone. The most common examples of these drugs are Boniva and Fosamax.
- Conditions
- Osteoporosis, With or Without Treatment, Bisphosphonate Treatment, Atypical Femur Fracture, Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ)
- Trial name
- NCT01875458
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Post Operative Pain
Post Operative Infusion Pump Pain Study
This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period..
- Trial name
- NCT07349810
- Testing
- Bupivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution, 1.3% liposomal bupivacaine (Exparel)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Preoperative Anxiety, Psychological Stress
Effect of Lavender Aromatherapy on Preoperative Anxiety, Stress, and Depression in Orthopedic Surgery Patients
This study evaluates whether inhalation aromatherapy with lavender essential oil can reduce anxiety, stress, and depression in adult patients before orthopedic surgery in Jordan.
- Conditions
- Preoperative Anxiety, Psychological Stress, Depressive Symptoms, Orthopedic Surgery Patients
- Trial name
- LAV-ORTHO (NCT07513831)
- Testing
- Lavender Essential Oil Inhalation
- Where
- Jordan
- Volunteers
- 128 people
- Sponsor
- Al-Zaytoonah University of Jordan
Hypothermia
Comparison of Forced Air and Conductive Patient Heating Systems During Ambulatory Surgeries
Comparison of forced air and conductive warming devices in outpatient orthopaedic surgeries.
- Trial name
- NCT02467777
- Testing
- Bair Hugger, VitaHeat
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fox Valley Orthopedic Institute
Postoperative Pain
Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery
The goal of this clinical trial] is to further explore the effectiveness and safety of oxelidine in the treatment of moderate to severe acute pain after orthopedic surgery.
- Trial name
- NCT06320041
- Testing
- Low dose oxelidine group, High dose oxelidine group, Hydromorphone group
- Where
- China
- Volunteers
- 162 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Orthopedic Disorder, Shoulder Pain
Peng Block or Suprascapular Nerve Block for Postoperative Analgesia in Shoulder Artroscopy ?
Arthroscopic shoulder surgery, which has been frequently applied in recent years, provides long-term positive clinical results and increases the quality of life after surgery, while it can cause severe pain in the early…
- Conditions
- Orthopedic Disorder, Shoulder Pain, Surgery, Analgesia
- Trial name
- NCT05666076
- Testing
- Pericapsular nerve block, Suprascapular nerve block, Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pain, Postoperative
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
The purpose of this study is to determine whether, for surgery of the tibia, one dose of methadone provides better control of pain afterward as compared to morphine, which is the usual drug given to control pain after surgery.
- Trial name
- NCT01430182
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Spinal Anesthesia, Total Knee Arthroplasty
Frontal QRS Axis Changes in Patients Undergoing Total Knee Arthroplasty With Spinal Anesthesia (FQRS-TKA)
This prospective, single-center, observational study aims to evaluate changes in the frontal QRS axis on ECG before and after spinal anesthesia in patients undergoing total knee arthroplasty.
- Trial name
- FQRS-TKA (NCT07112313)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sevim Şenol Karataş
Delirium, Anxiety
Effect of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Orthopaedic Surgery.
Postoperative delirium is a common and important complication in patients. The aim of this study was to investigate whether preoperative anxiety predicted onset of postoperative delirium in elderly patients undergoing orthopaedic…
- Trial name
- NCT04216615
- Testing
- preoperative anxiety
- Volunteers
- 290 people
- Sponsor
- Xuzhou Medical University
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Hip Fracture
A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for…
- Trial name
- NCT01547468
- Testing
- Femoral Nerve Catheterization, Intravenous Opioids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leslie Thomas
Cannabis, Marijuana
Analgesic Consumption in Chronic Marijuana Users Following Orthopedic Trauma Surgery
Marijuana use has increased since its legalization in Canada and many believe that it may help patients that are experiencing chronic pain.
- Trial name
- NCT04587700
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of Alberta
Postoperative Delirium
Preoperative Distress and Postoperative Delirium in Elderly Patients Undergoing Major Orthopedic Surgery
Postoperative delirium is a common and serious complication in elderly patients undergoing major orthopedic surgery and is associated with increased morbidity, prolonged hospital stay, and higher healthcare costs.
- Trial name
- NCT07512752
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi