Clinical trials: Orthopedic Surgery
Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow
Web Based Orthopaedic Sports Medicine Registry
The purpose of this study is to establish an international, web based clinical registry to collect baseline characteristics of patients undergoing orthopaedic, sports medicine, arthroscopy, and related surgery, and the subsequent…
- Conditions
- Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist
- Trial name
- NCT01191151
- Where
- 258 sites in United States, Canada and 3 more
- Volunteers
- 12,500 people
- Sponsor
- Arthrex, Inc.
Postoperative Delirium
Predictive Value of β2-microspheres for Postoperative Delirium
This study evaluated the predictive value of β2-microspheres for postoperative delirium (POD) in the elderly after orthopedic surgery.
- Trial name
- NCT03130231
- Where
- China
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Diabetes Mellitus, Type 2, Arthroplasty, Replacement, Hip
CGM Monitoring in T2DM Patients Undergoing Orthopaedic Replacement Surgery
The purpose of this study is to analyze the efficacy and accuracy of real-time continuous glucose monitoring devices (rtCGM) in patients with Type 2 diabetes undergoing inpatient elective hip or knee surgery in the pre-, peri…
- Conditions
- Diabetes Mellitus, Type 2, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT05666479
- Testing
- Dexcom G6 Pro Continuous Glucose Monitor (CGM)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stony Brook University
Opioid-induced Constipation
Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures
The purpose of this study is to examine the safety and activity of MNTX in relieving opioid-induced constipation following orthopedic procedures.
- Trial name
- NCT00640146
- Testing
- Methylnaltrexone bromide
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Bausch Health Americas, Inc.
Sarcopenia
Whole-body Electromyostimulation in Inpatient Rehabilitation
Based on various studies, scientific evidence has proven the effectiveness of whole-body electromyostimulation (WB-EMS) on parameters such as increased physiological performance and body composition.
- Trial name
- GERKO (NCT03767088)
- Testing
- WB-EMS, (synchronized) Training program without WB-EMS
- Where
- Germany
- Volunteers
- 134 people
- Sponsor
- Prof. Dr. Frank Mooren
Delirium, Pain
Pregabalin in the Prevention of Postoperative Delirium and Pain
The purpose of this study is to determine whether administration of pregabalin by mouth immediately preoperatively and three times daily for 3 days after surgery reduces the incidence of delirium postoperatively and improves…
- Trial name
- NCT00819988
- Testing
- Pregabalin, Sugar pill
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Ottawa Hospital Research Institute
Hemi Knee Arthroplasty, Patello-femoral Osteoarthritis
Evaluation of Orthopedic Knee Measurement Using Lunar iDXA
This study is to compare scans of the knee performed using new software designed specifically to look at the knee joint with those performed using approved software designed for scans of the hip.
- Trial name
- NCT01348958
- Testing
- iDXA knee software
- Where
- New Zealand
- Volunteers
- 36 people
- Sponsor
- GE Healthcare
Spinal Anesthesia, Intracranial Pressure Change
Effect of Spinal Needle Type on Optic Nerve Sheath Diameter
The optic nerve sheath is a continuation of the dura mater, extending along the subarachnoid space surrounding the optic nerve. Consequently, changes in intracranial pressure cause an augmentation or contraction in the diameter…
- Conditions
- Spinal Anesthesia, Intracranial Pressure Change, Optic Nerve Sheath Diameter, Orthopedic Surgery
- Trial name
- NCT06497634
- Testing
- 25 PP, 25 Q, 27 Q
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Bagcilar Training and Research Hospital
Bone Neoplasms, Soft Tissue Neoplasms
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue.
- Conditions
- Bone Neoplasms, Soft Tissue Neoplasms, Anxiety, Stress, Psychological
- Trial name
- BIOPSY-STRESS (NCT07727434)
- Testing
- Routine Diagnostic and Treatment Pathway
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Pain, Postoperative
Pain Management After Surgery
Following outpatient orthopaedic surgery, adequate pain control is imperative both for patient satisfaction and for improved recovery and rehabilitation.
- Trial name
- NCT05154682
- Testing
- OxyCODONE 5 mg Oral Tablet, Acetaminophen 500Mg Tab, Naproxen 500 Mg
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Scoliosis
Pharmacokinetics of Aminocaproic Acid in Scoliosis Surgery
This study will evaluate the pharmacokinetics of antifibrinolytic drug epsilon-aminocaproic acid (EACA) in children undergoing Posterior spinal fusion surgery (PSF) at The Children's Hospital of Philadelphia (CHOP) who receive…
- Trial name
- NCT01408823
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Hip Surgery
Effectiveness and Safety of the Electrically Powered Orthopedic Exercise Device on Gait Ability in Patients With Who Have Undergone Hip Surgery
Gait is an essential daily activity performed through the complex coordination of the central and peripheral nervous systems and the musculoskeletal system.
- Trial name
- NCT07147491
- Testing
- Electrically Powered Orthopedic Exercise Device
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Geriatric
Assessment for GEriatric Trauma Patients
Hip fracture is the second indication of surgical management elderly patients. It remains linked with a one-year mortality of 20%-25% according to diiferent governmental agencies, and the incidence reaches 30% for those over 80…
- Trial name
- PAGET (NCT03202589)
- Testing
- FOCUS Echocardiography
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Montpellier
Mental Health Issue, Mutism
Efficacy of Character Strengths Intervention in Enhancing Character Strengths and Self-esteem Among Adolescents
The goal of this study is to better understand the experiences of adolescents with physical disabilities and assess the effectiveness of a Character Strengths Intervention (CSI) in improving their self-esteem, character…
- Conditions
- Mental Health Issue, Mutism, Orthopedic Disorder
- Trial name
- (CSI) (NCT06080685)
- Testing
- Character Strengths Intervention
- Where
- 3 sites in Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Orthopedic Disorders, Trauma
A Survey of Google Glass by Orthopaedic Trauma Patients and Surgeons
Patients seen in the Orthopaedic Trauma clinic will be asked to consent for potential video/picture recording using the Google Glass device during their visit with the orthopaedic surgeon or resident.
- Trial name
- GoogleGlass (NCT02221115)
- Testing
- Google Glass
- Where
- Canada
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Traumatic Brain Injury, Orthopedic Injury
Epigenetic Effects on Traumatic Brain Injury Recovery
Methylation of the brain-derived neurotrophic factor (BDNF) gene is involved in both the biological encoding of childhood adversity and neuroplasticity following traumatic brain injury (TBI).
- Trial name
- EETR (NCT04186429)
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- University of Pittsburgh
Osteoarthritis of Knee
Outcome Following Orthopaedic Surgery
By investigating the long-term functional status of patients who have undergone various types of orthopaedic surgery we will have a basis for devising guidelines for future patients and surgeons.
- Trial name
- NCT00261066
- Where
- Canada
- Volunteers
- 8,439 people
- Sponsor
- Ottawa Hospital Research Institute
Orthopedic Surgery
Intraoperative Methadone for the Prevention of Postoperative Pain
The pain felt after orthopedic surgery in the absence of adequate locoregional anesthesia is often insufficiently controlled, especially during the first 24 hours postoperatively.
- Trial name
- NCT05831345
- Testing
- Methadone Hydrochloride, Sufentanil Citrate
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Brugmann University Hospital
Orthopedic Disorder, Metabolism and Nutrition Disorder
NUtrition and ORal Health in Orthopaedic Surgery
This prospective observational study evaluates the relationship between the objective oral health status and the patient reported diet in 64 adult patients undergoing elective major orthopaedic surgery (hip, knee, or spine…
- Trial name
- NCT06327854
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio