Clinical trials: Osteitis
Paget's Disease of Bone
18F-Fluoride Positron Emission Tomography (PET) in Paget's Disease of Bone
18 F-fluoride Positron emission tomography (PET) is able to demonstrate and quantify the metabolic activity locally in the skeleton (1).
- Trial name
- NCT00306046
- Testing
- Bisphosphonate treatment
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Catholique de Louvain
IBD, Inflammatory Bone Disease
Prediction of IBD Disease Activity in Individual Patients Based on PROMs and Clinical Data
The proposed study will use a PROM (Patient report Outcome Measurement)-tool in combination with clinical and biochemical data to train and validate a Relapse Prediction Model for individual patients.
- Trial name
- PrePro (NCT05578768)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Leiden University Medical Center
Pressure-related Osteitis
Pressure Sore-related Osteitis Treated by Flap Coverage and Short Antibiotic Regimen
Pressure ulcers associated with osteitis are frequent among patients with spinal cord injury (SCI), and optimal management is not well known.
- Trial name
- SCAR (NCT03964818)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Paget Disease, Paget Disease of Bone
Genetic Analysis to Predict the Development of Paget's Disease
Paget's disease of the bone (PDB) is a skeletal disorder with a strong genetic component which can be associated with various complications such as pain, bone deformity, arthritis and deafness.
- Trial name
- GAPDPD (NCT05309954)
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Paget's Disease of Bone
Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period
The core study looked at the effect of Zoledronic Acid given once as an intravenous (i.v.) infusion compared to 60 days of oral Risedronate in patients with Paget's disease of bone.
- Trial name
- NCT00051636
- Testing
- Zoledronic Acid, Risedronate, Calcium and Vitamin D
- Where
- 34 sites in United States, Australia and 4 more
- Volunteers
- 172 people
- Sponsor
- Novartis Pharmaceuticals
Impacted Third Molar
Comparative Effects of CGF and PRP in Impacted Third Molar Surgery
This study evaluates the effects of two different blood products obtained from the patient's own blood (Concentrated Growth Factor [CGF] and Platelet-Rich Plasma [PRP]) on healing after wisdom tooth extraction.
- Trial name
- NCT07320170
- Testing
- Concentrated Growth Factor (CGF), Platelet-Rich Plasma (PRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Recep Tayyip Erdogan University
Alveolar Osteitis, Pain
Investigation of the Effect of I-PRF Application on Pain in Alveolitis
Literature review showed that there are no studies on the use of i-PRF in alveolitis cases. The aim of this study was to investigate the effect of i-PRF on the treatment of alveolitis.
- Conditions
- Alveolar Osteitis, Pain, Dry Socket
- Trial name
- NCT06761001
- Testing
- I-PRF, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Alveolar Osteitis, Dry Socket
Antibiotic Efficacy in Third Molar Surgery
Despite over 50 years of antibiotic use and multiple clinical investigations (>50), no definitive studies exist to confirm or refute the use of systemic antibiotics to prevent postoperative inflammatory complications after third…
- Conditions
- Alveolar Osteitis, Dry Socket, Infection
- Trial name
- NCT00118820
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alveolar Osteitis
Use of PRF in Treatment of Dry Socket.
The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.
- Trial name
- NCT04476121
- Testing
- PRF application, Nipas application
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Osteosarcoma, Paget's Disease
Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18:
Researchers have previously demonstrated loss of heterozygosity in a region on chromosome 18q, associated with osteogenic sarcomas in bone affected by Paget's disease.
- Trial name
- NCT00615628
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
Osteoporosis, Osteitis Deformans
Preliminary Study for Identification of Calcium-Binding Proteins in the Serum in Various Metabolic Bone Disorders
The purpose of this study is to determine whether the serum levels of certain calcium-binding proteins may be helpful in the diagnosis and management of metabolic bone diseases.
- Conditions
- Osteoporosis, Osteitis Deformans, Parathyroid Diseases
- Trial name
- NCT00403598
- Where
- Israel
- Sponsor
- Sheba Medical Center
Alveolar Osteitis
Does the Use of HA Gel Following Third Molar Extraction Decrease the Incidence of Alveolar Osteitis?
The study aimed to investigate the effectiveness of Hyaluronic Acid gel on decreasing the incidence of alveolar osteitis after mandibular third molar extraction.
- Trial name
- NCT07139340
- Testing
- HA gel
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Osteitis, Cranial Flap
Bone Flap Osteomyelitis Following Craniectomy : Retrospective Evaluation of Clinical Presentation, Microbiological Diagnosis and Management
Osteitis of the cranial flap after craniectomy is an unknown complex osteoarticular infection and there are few data concerning its epidemiology, its risk factors, and its management.
- Trial name
- BoFOC (NCT05367713)
- Testing
- patients having had an osteitis of the cranial flap after craniectomy
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Hospices Civils de Lyon
Osseous Paget's Disease
Sodium Risedronate Tablets - Special Drug Use Surveillance in Patients With Osseous Paget's Disease (All-case Surveillance) -48-week Surveillance -
The purpose of this study is to evaluate the safety and efficacy of sodium risedronate tablets administered once daily (one tablet per dose) in patients with osseous Paget's disease for 48 weeks from baseline in daily medical…
- Trial name
- NCT02106455
- Testing
- Sodium risedronate
- Where
- 2 sites in Japan
- Volunteers
- 315 people
- Sponsor
- Takeda
Chronic Recurrent Multifocal Osteomyelitis
Post-transition Clinical and Socio-professional Future in Adult Patients With Recurrent Multifocal Chronic Osteitis
Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare autoinflammatory bone disease in children. Studies evaluating the quality of life of patients with CRMO are small and heterogeneous.
- Trial name
- ESPERANTO (NCT05103137)
- Testing
- Questionnaire
- Where
- 3 sites in France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
Post-Operative Wound Infection
A Tetracycline Drain Reduces Alveolar Osteitis in Third Molar Surgery
The aim of this study was to investigate the effect of an oxytetracycline impregnated gauze drain on the incidence of alveolar osteitis (AO) and postoperative pain during the first week after mandibular third molar surgery.
- Trial name
- Wisdomsteeth (NCT03494972)
- Testing
- Tetracyclin ointment
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Paget's Disease of Bone
Pathophysiology of Paget's Disease of Bone
Paget's disease of the bone is a skeletal disorder which results in increased and disorganized bone remodeling, leading to dense but fragile and expanding bones.
- Trial name
- NCT02802384
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Paget's Disease of Bone
Efficacy and Safety of Single Dose of 5 mg Zoledronic Acid in Chinese Patients With Paget's Disease of Bone (PDB)
The purpose of this study is to document the efficacy and safety profiles of single intravenous dose of 5 mg zoledronic acid for the Chinese patients of Paget's Disease of Bone (PDB).
- Trial name
- NCT00774020
- Testing
- Zoledronic acid
- Where
- 4 sites in China
- Volunteers
- 9 people
- Sponsor
- Novartis Pharmaceuticals
Alveolar Osteitis
Clinical Investigation of the Efficacy of CGF and Ozone in the Treatment of Alveolar Osteitis
The aim of this study is to investigate the efficacy of CGF and Ozone in the treatment of alveolitis and to develop a new treatment protocol that can enable a quick and effective solution of this clinical problem, which…
- Trial name
- NCT04507009
- Testing
- Ozone, CGF, Traditional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ordu University
Neoplasms, Breast
Lapatinib and Bevacizumab for Metastatic Breast Cancer
This study will examine the efficacy and safety of lapatinib and bevacizumab in patients with ErbB2-overexpressing breast cancer.
- Trial name
- NCT00444535
- Testing
- lapatinib, bevacizumab
- Where
- 9 sites in United States
- Volunteers
- 52 people
- Sponsor
- Novartis Pharmaceuticals