Clinical trials: Osteitis
Paget's Disease of Bone
Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period
The primary objective of this core study was to show non-inferiority of zoledronic acid to risedronate, with respect to the proportion of patients who achieved therapeutic response.
- Trial name
- NCT00103740
- Testing
- zoledronic acid, Risedronate, Calcium and vitamin D supplements
- Where
- 41 sites in United States, Australia and 8 more
- Volunteers
- 185 people
- Sponsor
- Novartis Pharmaceuticals
Alveolar Osteitis, Impacted Lower Third Molar
Chlorhexidine Versus Normal Saline Socket Irrigation for Prevention of Dry Socket After Lower Wisdom Tooth Extraction
Dry socket, also called alveolar osteitis, is a painful complication that can occur after tooth extraction, particularly following removal of impacted lower wisdom teeth.
- Trial name
- NCT07814430
- Testing
- Chlorhexidine Socket Irrigation, Normal Saline Socket Irrigation
- Where
- Pakistan
- Volunteers
- 174 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Alveolar Osteitis
Alvogyl Versus Platelet-Rich Fibrin for Healing of Alveolar Osteitis
Alveolar osteitis, commonly known as dry socket, is a painful complication that can occur after tooth extraction, particularly following removal of a mandibular third molar.
- Trial name
- NCT07790653
- Testing
- Alvogyl Dressing, Platelet-Rich Fibrin (PRF)
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Chondrocalcinosis, Articular Cartilage Calcification
Ultrasound and X-ray in Detecting Articular Cartilage Calcification
Prospective study with an echography of the 2 knees and radiography of the 2 knees (front and profile) for each patient. If found calcification on ultrasound further examination with ultrasound wrists, hips and shoulders.
- Trial name
- chondro (NCT00797537)
- Testing
- Echography
- Where
- France
- Volunteers
- 166 people
- Sponsor
- University Hospital, Limoges
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Osteogenesis Imperfecta, Osteoporosis
Bisphosphonate Therapy for Osteogenesis Imperfecta
The study is designed to evaluate the efficacy and safety of "Bisphosphonate Therapy for Osteogenesis Imperfecta (OI)." We, the researchers at Indiana University School of Medicine, are characterizing the changes effected by oral…
- Conditions
- Osteogenesis Imperfecta, Osteoporosis, Paget Disease of Bone
- Trial name
- NCT00159419
- Testing
- Alendronate, Pamidronate
- Volunteers
- 18 people
- Sponsor
- Indiana University
Paget's Disease of the Bone
Re-treatment of Participants With Paget's Disease Using Zoledronic Acid
The purpose of this study was to demonstrate that participants with Paget's disease of the bone who had responded to zoledronic acid treatment as participants in the core registration studies CZOL446K2304 and CZOL446K2305 and…
- Trial name
- NCT00740129
- Testing
- Zoledronic Acid
- Where
- 11 sites in Belgium, Canada and 4 more
- Volunteers
- 6 people
- Sponsor
- Novartis Pharmaceuticals
HIV Positive
Bone, Inflammation, Gut and Renal Biomarkers in Antiretroviral Naïve HIV-1 Positive Subjects
Co-morbidities, including low bone mineral density, increased visceral adiposity and chronic kidney disease (CKD) are frequent in people living with HIV, and may be driven by ongoing inflammation and immune activation.
- Trial name
- BIGGER (NCT03660722)
- Testing
- blood and urinary samples
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Alveolar Osteitis
Photo Biomodulation Therapy for Alveolar Osteitis Recovery in Oral Contraceptive Users
does laser effect on alveolar osteitis recovery in oral contraceptive users ?
- Trial name
- NCT06865508
- Testing
- Laser therapy, zinc oxide eugenol dressing.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Badr University
Dry Socket
Impact of Treatment With ALVEOGYL in Patients With Post-extraction Dry Socket
Alveogyl (Septodont, Saint-Maur-des-Fossés - France) is a Medical Device used as dressing in case of dry socket. ALVE study is a clinical investigation measuring Alveogyl performance and safety in patients with post-extraction…
- Trial name
- NCT05536115
- Testing
- Alveogyl
- Where
- 16 sites in France, India
- Volunteers
- 120 people
- Sponsor
- Septodont
SAPHO Syndrome
Characterizing SAPHO With 68Ga-FAPI PET/CT
68Ga-FAPI has been developed as a tumor-targeting agent as fibroblast activation protein is overexpressed in cancer-associated fibroblasts and some inflammation.
- Trial name
- NCT04596462
- Testing
- 68Ga-FAPI
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking Union Medical College Hospital
Osteitis Pubis
Manual Therapy for the Treatment of Athletic Pubalgia
Athletic osteitis pubis is a high prevalent pathology among athletes, especially in those who make quick change of direction of the movement, like runners or footballers.
- Trial name
- NCT05712486
- Testing
- High force hip Lateral distraction
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Valladolid
Paget's Disease of Bone
Genetic Study of Families Affected by Paget's Disease of Bone
Paget's disease of bone is a frequent bone disorder which usually starts after the age of 40 and which is characterized by bone pain and deformities.
- Trial name
- PAGET (NCT00747994)
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Immune System Disease, Musculoskeletal Disease
Chronic Non-bacterial Osteomyelitis Treated With Pamidronate
In a randomized double blind placebo controlled trial to investigate the effect of pamidronate in treatment of chronic non bacterial osteomyelitis. Main objective: 1.
- Trial name
- CNOPAM (NCT02594878)
- Testing
- Pamidronatdinatrium, Natrium chloride 9mg/ml
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Aarhus
Neoplasms, Breast
Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study
This is a randomised, open label multicenter Phase III study comparing the efficacy of neoadjuvant lapatinib plus paclitaxel, versus trastuzumab plus paclitaxel, versus concomitant lapatinib and trastuzumab plus paclitaxel given…
- Trial name
- Neo ALTTO (NCT00553358)
- Testing
- Lapatinib, Trastuzumab, Paclitaxel
- Where
- 121 sites in Argentina, Belgium and 22 more
- Volunteers
- 455 people
- Sponsor
- Novartis Pharmaceuticals
Osteitis Pubis, Athletic Pubalgia
Effects of Manual Therapy in Strenght, Pain and Functional Capacity for Sport Related Groin Pain
Athletic osteitis pubis is a pathologic entity that can cause functional impairment. Scientific evidence have noticed that athletes experiment pain and a decrease on strength.
- Trial name
- NCT05716204
- Testing
- High force lateral distraction
- Where
- Spain
- Sponsor
- University of Valladolid
Alveolar Osteitis
First-in-man Study of Adult Patients Suffered From Alveolar Osteitis Treated Using Stomatological Tamponade Contipro
Alveolar Osteitis (AO) is a complication following extraction of a tooth. AO manifests by localized pain in and around the extraction site where the postoperative blood clot has been disintegrated.
- Trial name
- NCT04091399
- Testing
- Stamatological tamponade Contipro
- Where
- 11 sites in Czechia
- Volunteers
- 58 people
- Sponsor
- Contipro Pharma a.s.
Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia, Paget Disease of Bone
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
The investigators are researching families with inherited inclusion body myopathy (IBM) and/or Paget disease of bone (PDB) and/or dementia (FTD) which is also called IBMPFD. IBMPFD is caused by mutations in the VCP gene.
- Conditions
- Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia, Paget Disease of Bone, Frontotemporal Dementia, Myopathy
- Trial name
- NCT01353430
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
SAPHO Syndrome
Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome
This study is designed to evaluate long term efficacy of intravenous bisphosphonates for bone marrow edema in patients with SAPHO syndrome.
- Trial name
- NCT02544659
- Testing
- pamidronate disodium
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Alveolar Osteitis
NBF Gingival Gel Application After Impacted Lower Third Molar Surgery
Background: Alveolar osteitis is one of the most frequent complications after lower third molar extraction, and is usually accompanied by inflammation, pain and poor wound healing.
- Trial name
- NCT03641482
- Testing
- NBF
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid