Clinical trials: Osteoarthritis, Knee/Rehabilitation
Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty Biomechanics
In total knee arthroplasty (TKA), the relationship between implant design, soft tissue balance, neuromuscular contributions, and rehabilitation strategies on patient satisfaction and functional outcomes is highly complex and…
- Trial name
- NCT03671954
- Testing
- Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments
- Where
- 4 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Florida
Rehabilitation, Excercise
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis.
- Conditions
- Rehabilitation, Excercise, Geriatric, Physical Therapy
- Trial name
- 5Ms/PT/KOA/OA (NCT07640529)
- Testing
- Geriatric 5Ms framework, Exercises PT
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Orthopedic, Osteo Arthritis Knee
Energy Status and Protein Intake As Prognostic Indicators of Rehabilitative Outcomes
The proposed project is novel in its goal to establish a foundation for evidence-based rehabilitative nutrition guidelines to enhance perioperative patient care and improve post-operative rehabilitative outcomes specific to…
- Conditions
- Orthopedic, Osteo Arthritis Knee, Hip Osteoarthritis, Protein-Energy Malnutrition
- Trial name
- ESPI-PRO (NCT06734845)
- Testing
- Total Knee Arthroplasty, Total Joint Arthroplasty
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Knee Arthritis Osteoarthritis
Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities
This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis.
- Trial name
- HILT-CM (KOA) (NCT07551245)
- Testing
- High-Intensity Laser Therapy (HILT), Conventional Physical Therapy Modalities
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erbil Polytechnic University
Knee Osteoarthritis
Experience and Technology Acceptance of Older Adults Towards a Gamified Rehabilitative Device Prototype
Title: Older adults' experience and acceptance of a 'gamified' rehabilitative device for Total Knee Arthroplasty Background: Total Knee Arthroplasty (TKA) is a common surgical procedure.
- Trial name
- NCT04059744
- Testing
- Fun-Knee
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Knee Osteoarthritis
Effects of Virtual Reality Environments on Walking in Adults With and Without Knee Osteoarthritis
Knee osteoarthritis (KOA) is a common musculoskeletal condition associated with pain, impaired physical function, and movement-related fear.
- Trial name
- NCT07920120
- Testing
- Immersive Virtual Reality Walking Conditions, Non-VR Walking
- Where
- 2 sites in Lithuania, Slovenia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Total Knee Arthroplasty, Osteoarthritis
Blood Flow Restriction Training Following Total Knee Arthroplasty
This study will evaluate blood flow restriction training as a rehabilitation modalities following total knee arthroplasty in order to determine if patient reported outcomes and objective functional outcomes can be improved…
- Trial name
- NCT02763488
- Testing
- DelfiPTS tourniquet system, Standard physical therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Osteoarthritis, Knee
Study of the KinexConnect Telerehabilitation System (KCTRS)
A randomized, single-blind study comparing telerehabilitation at home with continuous passive motion (CPM) and a tablet-based patient engagement application (KinexConnect) versus traditional outpatient physical therapy (PT)…
- Trial name
- KCTRS (NCT04191798)
- Testing
- Telerehabilitation using the KinexConnect system for rehabilitation after TKA., Traditional outpatient PT for rehabilitation after TKA.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kinex Medical Company, LLC
Sport Injury, Osteoarthritis, Knee
Biometric Recognition and Rehabilitation Assessment of Lower Extremity Sports Injury Based on Gait Touch Information
The current common clinical methods cannot truly reflect the biomechanical status of the knee joint. Based on the foot-knee coupling mechanism, the simple and practical dynamic gait touch information provided by the 3D force…
- Trial name
- NCT04462913
- Testing
- no intervention
- Where
- China
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Total Knee Arthroplasty, Knee Osteoarthritis
Patient-navigation-based Preoperative Rehabilitation Exercise Program in Patients Undergoing TKA
This study aimed to assess the effectiveness of a patient navigation-based preoperative rehabilitation exercise program for patients undergoing total knee arthroplasty.
- Trial name
- NCT07047079
- Testing
- Autonomous preoperative rehabilitation exercises, The navigator provided full-period preoperative rehabilitation exercise guidance+navigation services
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Anna Sun
Osteoarthritis, Knee, Product Use Issue
Evaluation of Product Effectiveness of the Intervention for Patients With Knee Osteoarthritis
Osteoarthritis of the knee is a common, chronic joint pathology that causes participants to suffer from pain, dysfunction, and reduced quality of life.
- Conditions
- Osteoarthritis, Knee, Product Use Issue, Sports Physical Therapy
- Trial name
- NCT06220565
- Testing
- sensor and wearable device "Graded Exercise", exercise, Educational Manual
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Rehabilitation, Treatment Outcome
Effects of Exercise Therapy and Soft Brace on Knee Osteoarthritis
The primary aim of the study is to investigate the effects of supervised exercise therapy and education on the immediate response to using a soft knee brace in patients with knee osteoarthritis (OA).
- Conditions
- Rehabilitation, Treatment Outcome, Pain, Knee Brace
- Trial name
- NCT03949400
- Testing
- Exercise therapy and education.
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College of Northern Denmark
Knee Osteoarthritis
Corticospinal Excitability and Rehab in Knee Osteoarthritis
To determine differences in thigh muscle function in individuals with and without knee arthritis, and also determine the effectiveness of common physical therapy interventions on clinical and patient oriented outcomes.
- Trial name
- NCT02036866
- Testing
- Transcutaneous Electrical Nerve Stimulation, Physical Therapy Exercises, No Intervention
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Creighton University
Knee Pain Chronic, Knee Osteoarthritis
Prevention, Management and Rehabilitation of Knee Osteoarthritis at the Workplace
The goal of this intervention study is to assess the effect of blood flow restricted (BFR) exercise integrated into the daily work tasks among hospital workers with or at increased risk of chronic knee pain.
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Knee Discomfort
- Trial name
- NCT05822401
- Testing
- Blood flow restriction (BFR), Usual care (control)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Congestive Heart Failure
Exercise-based Cardiac Rehabilitation in Congestive Heart Failure With Coexisting Knee Osteoarthritis
Exercise-based cardiac rehabilitation (CR) has been shown to significantly improve cardiovascular health and overall well-being in patients with congestive heart failure (CHF).
- Trial name
- NCT07440914
- Testing
- Exercise Based Cardiac Rehabilitation, Controlled Group
- Where
- Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Gonarthrosis
Intraarticular Collagen in Patients With Gonarthrosis
The objective of this clinical trial is to verify the effectiveness of polyvinyl pyrrolidone collagen in all patients with symptomatic gonarthrosis grades II-IV in patients over 40 years of age.
- Trial name
- NCT06275880
- Testing
- Intra-articular infiltration of PVP Collagen, Rehabilitation
- Where
- Mexico
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Knee Arthritis, Osteoarthritis
Knee Osteoarthritis Rehabilitation Through Rotational Inertia
This study is testing whether a new type of exercise program, called eccentric overload training using a flywheel device, can improve stair-climbing ability in people with knee osteoarthritis.
- Trial name
- KORRI (NCT07424352)
- Testing
- Eccentric resistance training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoarthritis
Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation
The general hypothesis is that in older adults muscle regrowth after an acute musculoskeletal stress will be positively influenced by traditional physical rehabilitation, and further enhanced by nutritional supplementation.
- Trial name
- NCT00760383
- Testing
- Essential amino acids, Alanine
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Knee Osteoarthristis, Healthy Adults
Digital Course and Precision Rehabilitation for Knee Osteoarthritis and Older Adults: Integration of Multisensory Stimulation and Digital Twin Technology
Knee osteoarthritis (OA) is a common degenerative joint disease in middle-aged and older adults and is frequently associated with pain, quadriceps weakness, reduced mobility, impaired proprioception, balance deficits, and…
- Trial name
- NCT07695168
- Testing
- digital rehabilitation exercise courses combined with multisensory stimulation, Home exercises based on therapist education, Gait retraining combined with neuromuscular electrical stimulation
- Where
- 3 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital