Clinical trials: Osteoarthritis, Spine
Spondyloarthritis
99mTc-rhAnnexin V-128 in Diagnosis of Spondyloarthritis
This single center, open-label, proof of concept (PoC) Phase II study aimed to assess the investigational imaging agent 99mTc-rhAnnexin V-128 in detecting spondyloarthritis (SpA) lesions.
- Trial name
- Annexin 03 (NCT03232580)
- Testing
- rhAnnexin V-128
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Advanced Accelerator Applications
Spondylodiscitis
Spondylodiscitis: a Retrospective Observational Study.
Spondylodiscitis is an infectious process affecting the vertebral bodies, intervertebral discs, and paraspinal tissues, sometimes involving the spinal cord, most often with a bacterial etiology.
- Trial name
- SpAl (NCT07164235)
- Testing
- Patients diagnosed with spondylodiscitis
- Where
- Italy
- Volunteers
- 137 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Ankylosing Spondylitis
Bawei Shenqi Pill in the Treatment of Ankylosing Spondylitis
The purpose of this study is to determine whether Bawei Shenqi Pill is effective in the treatment of active ankylosing spondylitis (AS).
- Trial name
- NCT04480359
- Testing
- Bawei Shenqi Pill, Meloxicam
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Arthritis, Reactive, Arthritis, Rheumatoid
Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients
This study will evaluate the 2-5 year outcome of a cohort of 250 patients with early synovitis, who were recruited into protocol 94-AR-0194 (The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis).
- Conditions
- Arthritis, Reactive, Arthritis, Rheumatoid, Synovitis
- Trial name
- NCT00001679
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Axial Spondyloarthritis
Walking Football for Axial Spondyloarthritis
Axial spondyloarthritis (axSpA) is a long-term inflammatory condition affecting the spine. Patients with this condition can have pain and stiffness in their back and neck.
- Trial name
- KICK START AS (NCT07414823)
- Testing
- Walking Football
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Spondyloarthropathies, Ankylosing Spondylitis
Efficacy of Pain Neuroscience Education and Physiotherapy in Patients Diagnosed with Spondyloarthritis
Spondyloarthritis, notably ankylosing spondylitis (AS), represents a chronic rheumatic condition typified by persistent back pain and stiffness.
- Trial name
- NCT06369324
- Testing
- Pain education, Exercise supervised by external focus, Therapy by means of electrical stimulation (electro-massage)
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Universidad de Extremadura
Axial Spondyloarthritis, Ankylosing Spondylitis (AS)
Effects of Pulmonary Rehabilitation Exercises in Patients With Axial Spondyloarthritis
This prospective, randomized, single-blind controlled study evaluates the effects of pulmonary rehabilitation exercises in patients with axial spondyloarthritis. Participants were randomized into two groups.
- Trial name
- NCT07847879
- Testing
- Pulmonary Rehabilitation Program, Conventional Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
PsA Patients Fulfilling CASPAR Criteria in Remission
Disparity Between Ultrasound- and Clinical Findings in Psoriatic Arthritis in Remission
Comparison of the proportion of Psoriatic arthritis patients in ultrasound remission (i.e. no power Doppler synovitis, tenosynovitis, dactylitis, enthesitis, PD=0) depending on whether patient and physician's global assessment of…
- Trial name
- PARURE (NCT03396679)
- Testing
- Ultrasound examination
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Montpellier
Ankylosing Spondylitis
Ustekinumab for the Treatment of Patients With Active Ankylosing Spondylitis
This study is aimed at investigation of efficacy and safety of ustekinumab (monoclonal antibody against interleukin 12 and 23) treatment in patients with active ankylosing spondylitis (AS) fulfilling the modified New York…
- Trial name
- TOPAS (NCT01330901)
- Testing
- Ustekinumab
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Charite University, Berlin, Germany
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Rheumatoid Arthritis, Ankylosing Spondylitis
Post-marketing Observational Study to Evaluate the Incremental Impact of AbbVie's Patient Support Program on Patient Reported Outcomes and Health Resource Utilization in Inflammatory Arthritis, Psoriasis and Inflammatory Bowel Diseases in Hungary (VALUE)
The objective of this post-marketing observational study (PMOS) was to evaluate the effectiveness of adalimumab plus the AbbVie Care 2.0 patient support program in participants with rheumatoid arthritis (RA), ankylosing…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis
- Trial name
- VALUE (NCT02750800)
- Testing
- Adalimumab, AbbVie Care 2.0
- Volunteers
- 427 people
- Sponsor
- AbbVie
EARLY UNDIFFERENTIATED SPONDYLARTHROPATHIES
French Cohort of Undifferentiated Spondyloarthritis
This study is a large national multicenter, longitudinal, prospective follow-up of patients presenting with early inflammatory back pain in order to set up a database to facilitate several investigations on diagnosis, prognosis…
- Trial name
- DESIR (NCT01648907)
- Testing
- Imaging exams
- Where
- France
- Volunteers
- 708 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ankylosing Spondylitis
Study to Examine the Clinical Efficacy and the Nonsteroidal Anti-inflammatory Drug (NSAID)-Sparing Effect of Secukinumab Over 16 Weeks in Patients With Ankylosing Spondylitis
This study assessed the clinical Assessment of SpondyloArthritis international Society (ASAS) 20 response to secukinumab and evaluated to which extent concomitant nonsteroidal anti-inflammatory drug (NSAID) treatment can be…
- Trial name
- ASTRUM (NCT02763046)
- Testing
- Secukinumab (AIN457) 150 mg s.c.
- Where
- 39 sites in Germany
- Volunteers
- 211 people
- Sponsor
- Novartis Pharmaceuticals
Spondyloarthritis, Axial and Peripheral
A Study in Participants With a Newly Confirmed Diagnosis of Spondyloarthritis (SpA) Who Are New to Conventional, Targeted and Biological DMARDs
The purpose of this Italian multicenter study is to collect prospective clinical data in participants with first diagnosis or confirmation diagnosis of Spondyloarthritis (SpA), according to Assessment of Spondyloarthritis…
- Trial name
- SIRENA (NCT03131661)
- Where
- 25 sites in Italy
- Volunteers
- 351 people
- Sponsor
- Janssen-Cilag S.p.A.
Ankylosing Spondylitis
Efficacy and Safety of Yuxuebi Tablet in Treating Night Pain of Ankylosing Spondylitis (AS).
This study is a multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of Yuxuebi tablet in treating night pain of Ankylosing Spondylitis.
- Trial name
- NCT04934059
- Testing
- Yuxuebi tablet
- Where
- 5 sites in China
- Volunteers
- 60 people
- Sponsor
- China Resources Sanjiu Medical & Pharmaceutical Co., Ltd.
Ankylosing Spondylitis
Epicardial Adipose Tissue Thickness and the Related Factors in Patients With Ankylosing Spondylitis
The aim of this study was to assess the EATT and the related factors in patients with AS and to compare the results with that of the healthy controls'
- Trial name
- NCT06094686
- Testing
- epicardial adipose tissue thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Ankylosing Spondylitis
Ankylosing Spondylitis
The goal of this observational study is to measure the serum level of cytokines IL-17, IL-38,IL-41, and gene expression of HLA-B27 gene in ankylosing spondylitis patients and healthy control group.
- Trial name
- Interleukins (NCT07396194)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rheumatoid Arthritis, Psoriatic Arthritis
Mindfulness Based Stress Reduction in Rheumatic Diseases
This study will assess the mental health and clinical benefits of Mindfulness Based Stress Reduction (MBSR) in patients with rheumatic disease who have anxiety or depression.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Scleroderma
- Trial name
- MBSR (NCT03411057)
- Testing
- Mindfulness Based Stress Reduction (MBSR), Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Ovarian Diseases, Ankylosing Spondylitis
Ovarian Reserve and Ankylosing Spondylitis
The aim of this study was to determine the status of ovarian reserve in patients with ankylosing spondylitis (AS) using anti-mullerian hormone (AMH) level and antral follicle count (AFC).
- Conditions
- Ovarian Diseases, Ankylosing Spondylitis, Anti-Mullerian Hormone Deficiency
- Trial name
- NCT04209881
- Testing
- ovarian reserve for Ankylosing spondylitis and control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Arthritis, Rheumatoid, Arthritis, Psoriatic
PANLAR's Latin American Registry of Rheumatic Patients Treated With Jak Inhibitors
This prospective, non-interventional, research registry is designed to study the comparative safety and comparative effectiveness of approved Jak Inhibitors treatment for RA-PsA-SpA in a cohort of patients and theirs controls…
- Conditions
- Arthritis, Rheumatoid, Arthritis, Psoriatic, Spondyloarthritis
- Trial name
- PREJAK (NCT04821206)
- Testing
- DMARDs, biologic DMARDs, JAK Inhibitor
- Where
- 2 sites in Argentina
- Volunteers
- 3,000 people
- Sponsor
- Liga Panamericana de Asociaciones de Reumatologia (PANLAR)
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