Clinical trials: Osteoarthritis (OA)
Osteoarthritis
Safety and Efficacy of Autologous SVF Cells in Treating Patients With Osteoarthritis
it's a self-control, double blind study of autologous adipose-derived stromal vascular fraction (SVF) to treat 50 osteoarthritic knees of grade II or III (K-L scale) under IRB-approved protocol in a feasibility and safety study.
- Trial name
- NCT02846675
- Testing
- autologous SVF
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai East Hospital
Osteoarthritis, Knee
Osteoarthritis Knee Pain Relief Study of 0.25% 920-CGS-200
This is a study of an over-the-counter, capsaicin-based (0.25%) topical analgesic for management of osteoarthritis knee pain meeting the US Food and Drug Administration's (FDAs) Tentative Final Monograph (TFM) guidance for…
- Trial name
- NCT03124407
- Testing
- Capsaicin Topical Solution, Drug product vehicle
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Propella Therapeutics
Arthritis, Osteoarthritis
Tanezumab in Osteoarthritis Of The Hip
The purpose of this study is to test the efficacy and safety of 3 doses of tanezumab in osteoarthritis of the hip in patients
- Conditions
- Arthritis, Osteoarthritis, Osteoarthritis, Hip
- Trial name
- NCT00744471
- Testing
- tanezumab
- Where
- 99 sites in United States
- Volunteers
- 627 people
- Sponsor
- Pfizer
Osteoarthritis (OA) of the Knee
Photographic Evidence on Total Knee Arthroplasty Outcomes
Historically, total knee arthroplasty (TKA) has been performed to restore knee range of motion and relieve pain, with postoperative rehabilitation focused on helping patients regain mobility and function.
- Trial name
- NCT07223359
- Testing
- Photographic Evidence of Postoperative Knee Range of Motion, Standard Postoperative Care
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Loyola University
Knee Arthritis Osteoarthritis
Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities
This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis.
- Trial name
- HILT-CM (KOA) (NCT07551245)
- Testing
- High-Intensity Laser Therapy (HILT), Conventional Physical Therapy Modalities
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erbil Polytechnic University
Osteoarthritis; Primary, Degenerative Joint Disease of Knee
A Multidisciplinary Intervention in Total Knee Arthroplasty
The purpose of this study is to investigate the effectiveness of cognitive behavioral therapy delivered as an e-therapy program, combined with physical exercise delivered by physiotherapists, for patients on waiting list for…
- Trial name
- MultiKnee (NCT03771430)
- Testing
- Osteoarthritis education, exercise and CBT, Total Knee Arthroplasty
- Where
- 3 sites in Norway
- Volunteers
- 282 people
- Sponsor
- Lovisenberg Diakonale Hospital
Chronic Osteoarthritis Pain, Chronic Low Back Pain
Study of PIPE-791 for Subjects With Chronic Osteoarthritis Pain or Chronic Low Back Pain
The primary goal of this clinical trial is to learn if PIPE-791 is safe and well-tolerated in adults with chronic osteoarthritis pain (COAP) or chronic low back pain (CLBP).
- Trial name
- NCT06810245
- Testing
- PIPE-791
- Where
- 5 sites in United States
- Volunteers
- 43 people
- Sponsor
- Contineum Therapeutics
Knee Osteoarthritis (Knee OA)
Knee OsteoArthritis Long-term Assessment
The goal of this clinical study is to learn if Hydrogel OA 2% injection is safe and whether it works to improve symptoms of diagnosed knee osteoarthritis in adults when compared to Hyaluronic Acid (Durolane), a treatment that is…
- Trial name
- KOALA (NCT06839222)
- Testing
- Hydrogel OA 2%, Hyaluronic Acid (Durolane)
- Where
- 5 sites in Belgium
- Sponsor
- Allegro NV/SA
Osteoarthritis, Spinal Arthritis
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for OA
This trial will study the safety and efficacy of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells delivered intravenously and intraarticularly for the treatment of Osteoarthritis.
- Trial name
- NCT05147675
- Testing
- AlloRx
- Where
- 2 sites in United States, Greece
- Volunteers
- 92 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Osteoarthritis, Arthritis
Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip
The purpose of this study is to investigate the long-term analgesic efficacy and safety of tanezumab for patients with osteoarthritis (OA) of the knee or hip currently experiencing partial benefit from, and are tolerating…
- Trial name
- NCT00809354
- Testing
- NSAID, tanezumab
- Where
- 333 sites in United States, Canada and 10 more
- Volunteers
- 2,720 people
- Sponsor
- Pfizer
Osteoarthritis Hand
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of STT Osteoarthritis
The aim of this open, prospective, multicenter trial is to evaluate the use of a sterile, devitalized, processed umbilical cord amniotic membrane implant placed in joint interposition in the treatment of STT osteoarthritis.
- Trial name
- NCT06038331
- Testing
- SclerFIX-IP
- Where
- 4 sites in France
- Volunteers
- 14 people
- Sponsor
- TBF Genie Tissulaire
Osteoarthritis of the Knee
Efficacy and Safety of 3 Different Dosage Regimens of Hyaluronic Acid in Patients With Knee Osteoarthritis (OA)
The main objective is the comparison of three different dosage regimens of hyaluronic acid in the treatment of osteoarthritis of the knee.
- Trial name
- NCT01290497
- Testing
- Hyaluronic acid 5 x 2.5 ml, Hyaluronic acid 1 x 5 ml, Hyaluronic acid 2 x 5 ml
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Tedec-Meiji Farma, S.A.
Knee Osteoarthritis
Live and Interactive Fitness Training Program (Vivo Knee OA)
Potential participants will be screened at clinic. Patients who meet eligibility criteria will be considered for study. After written informed consent is obtained, participants will complete baseline testing and participants who…
- Trial name
- LIFT-OA (NCT06462560)
- Testing
- Vivo Online Exercise Program, Medbridge Home program
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- Intermountain Health Care, Inc.
Knee Osteoarthritis \(OA\)
Motor Sparing Techniques, Genicular Nerve Radiofrequency Ablation Has Emerged As a Viable Alternative to Conservative Therapy and Total Knee Arthroplasty
There has recently been considerable interest in the role of radiofrequency ablation (RFA) of the genicular nerves for KOA. In the majority of previous studies, ablation was done via a radiofrequency technique using either…
- Trial name
- NCT06594003
- Testing
- Radiofrequency
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Osteoarthritis, Shoulder
TSA Techniques in Glenohumeral OA
Osteoarthritis (OA) of the shoulder is a disease resulting from the wearing down of cartilage over time. OA can produce pain and dysfunction at the affected joint and is a growing occurrence in an aging population.
- Trial name
- NCT02966886
- Testing
- Eccentric Reaming, Augmented Glenoid Component Implantation, Posterior Glenoid Bone Grafting
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis
A Study of the Tolerability of Titrated Dose Tramadol/Acetaminophen Combination Tablet in Korean Patients With Osteoarthritis
The purpose of this study is to compare the number of osteoarthritis patients receiving titrated or increasing doses of tramadol hydrochloride/acetaminophen combination tablet (titration group) who discontinue treatment due to…
- Trial name
- NCT01063842
- Testing
- tramadol hydrochloride /acetaminophen
- Volunteers
- 250 people
- Sponsor
- Janssen Korea, Ltd., Korea
Hip OA
Post-Market Clinical Follow-up of Intra-Articular Hyaluronic Acid in Hip Osteoarthritis
The study population consists of approximately 40 adult outpatients aged 40 years or older with symptomatic hip osteoarthritis of at least 1 year of clinical evolution, treated with intra-articular hyaluronic acid in routine…
- Trial name
- NCT07883395
- Where
- 4 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Meiji Pharma Spain S.A.
Osteoarthritis, Knee
Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With OA of the Knee
This is an open-label study assessing the effect of the administration of a single intra-articular (IA) injection of FX006 32 mg on synovial volume in patients with osteoarthritis (OA) of the knee.
- Trial name
- NCT03529942
- Testing
- FX006 32 mg
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 129 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Knee Osteoarthritis
Yoga Versus Exercises for Managing OA
The purpose of the study is to examine the short and long term effects of Hatha yoga compared to the current recommended exercise program in promoting physical function, alleviating osteoarthritis (OA)-related symptoms, fear of…
- Trial name
- YEMO (NCT02525341)
- Testing
- Hatha yoga, Aerobic and strengthening exercises, General education
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Minnesota
Osteoarthritis (OA) of the Knee
INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE
The goal of this clinical trial is to evaluate the effectiveness of Neural Ice for pain management associated with knee osteoarthritis in adults aged 22-80 years.
- Trial name
- ICE (NCT06700109)
- Testing
- Neural Ice, Triamcinolone acetate
- Where
- 15 sites in United States
- Volunteers
- 263 people
- Sponsor
- Brixton Biosciences, Inc.