Clinical trials: Osteoarthritis Arthritis
Pain, Osteoarthritis
Adductor Canal Block With Posterior Capsular Injection for Total Knee Replacement
To compare early ambulation and ability to participate in rehabilitation in patients undergoing total knee replacement using two different nerve block techniques for pain control.
- Trial name
- NCT01805661
- Testing
- Canal Block and Capsular Injection, Femoral with Tibial Nerve Block
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Trinity Health Of New England
Joint Disease
Post Market Clinical Follow-Up Study Protocol for CONSERVE® Press-Fit Femoral Components
MicroPort Orthopedics (MPO) is conducting this PMCF study to evaluate the safety and efficacy of its THA and resurfacing components marketed in the EU.
- Trial name
- NCT02285842
- Testing
- Primary hip resurfacing device
- Where
- Canada
- Volunteers
- 143 people
- Sponsor
- MicroPort Orthopedics Inc.
Osteoarthritis
A Study on Rosa Roxburghii for Knee Replacement Recovery
This clinical trail is to investigates the effect of Rosa roxburghii juice freeze-dried powder on the recovery of patients undergoing total knee arthroplasty due to knee osteoarthritis.
- Trial name
- NCT07395856
- Testing
- Rosa roxburghii
- Volunteers
- 184 people
- Sponsor
- Shuguang Gao
Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis
Could a Feedback Device Help Manage Work-related Shoulder Disorders?
Work-related shoulder pain is a common problem with significant socio-economic repercussions. The impact of these disorders on workers is considerable, particularly in terms of pain, disability and reduced quality of life.
- Conditions
- Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis, Rheumatoid Arthritis (RA)
- Trial name
- NCT06693479
- Testing
- Shoulder watch load (SWL) feedback, Education
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Laval University
Knee Osteoarthritis
Strength Training for ARthritis Trial
The primary purpose of this study is to compare the effects of a high and low intensity strength training programs vs. a control group on knee pain and compressive joint forces.
- Trial name
- START (NCT01489462)
- Testing
- High Intensity Strength Training, Low Intensity Strength Training, Attention Control
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- Wake Forest University
Osteoarthritis Pain
Study to Evaluate ATP-induced Pain and ATP-induced Dermal Vasodilation by Iontophoresis (0000-118)(COMPLETED)
This study will evaluate ATP-induced Pain (AIP) and ATP-induced dermal vasodilation (AIDV) as target engagement tools for future development of analgesics.
- Trial name
- NCT00917696
- Testing
- Comparator: Iontophoresis and Laser Doppler with ATP, Comparator: Iontophoresis and Laser Doppler with Saline
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Necrosis of Femoral Head, Knee Osteoarthritis
MRI Maker of Perioperative Neurocognitive Disorder
Periperative neurocognitive disorder(PND) is consistently associated with increased morbidity and mortality, but its mechanisms remain unclear.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Lower Limb
- Trial name
- MRIPND (NCT03773627)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Osteoarthritis Knees Both
The Synergistic Effects of Intra-articular Hyaluronic Acid and Platelet-rich Plasma Injections on Knee Osteoarthritis
Although intra-articular knee injection with platelet-rich plasma (PRP) may have better outcomes than using hyaluronic acid (HA) for people with knee osteoarthritis (OA), it is expensive to use PRP.
- Trial name
- HAPRP (NCT04443166)
- Testing
- A platelet-rich plasma (PRP)+ hyaluronic acid (HA) program
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Knee Osteoarthritis
Effect of Noise Control During Total Knee Arthroplasty
Music has emerged as a well-received medical intervention. Patients may be uncomfortable during total joint replacement, which can result in high sedation requirements. These requirements put patients at risk of surgical stress.
- Trial name
- NCT05714267
- Testing
- Active noise cancelling, Passive noice cancelling, Active noise cancelling with music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bezmialem Vakif University
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis
The goal of this study is to create a prospective registry (<100 patients) to show the effectiveness of the genicular artery embolization procedure overtime in reducing bilateral or unilateral osteoarthritic knee pain as measured…
- Conditions
- Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA)
- Trial name
- GAE (NCT06781463)
- Testing
- Registry (N/A)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Hip Osteoarthritis
Comparison of Hip Resurfacing and Cementless Metal-on-metal Total Hip Arthroplasty
To compare clinical, functional and radiological outcome after hip resurfacing and cementless metal-on-metal total hip arthroplasty.
- Trial name
- NCT00570167
- Testing
- Hip resurfacacing, Cementless total hip arthroplasty with m-o-m bearings
- Where
- 3 sites in Finland
- Volunteers
- 71 people
- Sponsor
- University of Helsinki
Rheumatoid Arthritis, Osteoarthritis
A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement
The purpose of this study is to monitor the performance and determine the metal ion release of the Pinnacle™ Cup with a metal-on-metal bearing combination in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208364
- Testing
- Pinnacle Acetabular Cup System
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 163 people
- Sponsor
- DePuy International
Osteoarthritis of the Knee
A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.
The primary objective of the study is to assess the effectiveness of alpha-D Glucosamine Sulfate/Standardized Extract of Ginkgo Biloba Leaf versus a comparator product on osteoarthritis pain as assessed by the between group…
- Trial name
- 13GOHJ (NCT02604381)
- Testing
- Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Extract
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- KGK Science Inc.
Osteoarthritis, Knee
Pre-operative Intravenous Steroid in Total Knee Replacement for Pain Relief and Recovery
Osteoarthritis of the knee is a common and important condition in our society. Despite various anesthetic methods and pain medications, pain after operation still remains as a challenge.
- Trial name
- NCT03082092
- Testing
- Methylprednisolone Sodium Succinate
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Knee Osteoarthritis, Knee Arthropathy
Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty
Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA).
- Trial name
- NCT06617871
- Testing
- Mechanical Alignment (MA), Kinematic Alignment (KA) Interventions:
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Northwestern University
Knee Osteoarthritis, Knee Arthroplasty
Development of an Outcome Score for Patients With Knee Osteoarthritis and Knee Joint Endoprosthesis Using an App
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) is one of the most frequent orthopedic procedures. Over 50% of patients report higher expectations than their surgeons, and 10-50% remain dissatisfied…
- Conditions
- Knee Osteoarthritis, Knee Arthroplasty, Hip Osteoarthritis, Hip Arthroplasty
- Trial name
- KneeApp (NCT07212699)
- Testing
- KneeApp
- Where
- Germany
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Knee Osteoarthritis
Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis
Knee osteoarthritis (OA) is the most prevalent form of arthritis and race is a risk factor for poor outcomes. African-Americans (AAs) report greater OA-related disability and pain severity compared to their Non-Hispanic White…
- Trial name
- NCT04343716
- Testing
- Low-carbohydrate diet
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis, Knee
Reinflation After Early Tourniquet Release in Total Knee Arthroplasty
This study is aimed to determine the efficacy and the safety of the tourniquet reinflation after early tourniquet release in total knee arthroplasty, compared to the method of early deflation without reinflation.
- Trial name
- NCT01832272
- Testing
- Reinflation after early tourniquet deflation
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Knee Osteoarthritis
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
The purpose of this study is to compare the clinical and functional outcomes of patients with mild to moderate arthroscopically confirmed osteoarthritis between the following two groups: 1.
- Trial name
- NCT03014401
- Testing
- Arthroscopic debridement with stem cell transplantation, Arthroscopic debridement only
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of Colorado, Denver
Knee Osteoarthritis
The Effects of Surgical Wait Time for Knee Arthroplasty Quality of Life in Patients Awaiting Knee Arthroplasty
This study prospectively evaluates the effect of surgical wait time on knee function, pain and quality of life in patients waiting for knee arthroplasty (TKA or PKA)
- Trial name
- SIT'NWAIT (NCT06127719)
- Testing
- questionnaires
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Dijklander Ziekenhuis
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