Clinical trials: Osteoarthritis Arthritis
Osteoarthritis, Knee, Chondral Defect
Evaluation of Treatment of Osteoarthritis of the Knee in the Form of Chondromalacia of the Articular Cartilage Treated in the Arthroscopic Technique With the Use of:Autogenous Transplantation of Fragmented Adipose Tissue,PRP GF,Mesenchymal Cells,Hyaluronic Acid-low Molecular Weight and Cross-linked
The main objective of the research project is to evaluate the results of the treatment of chondromalacia of the cartilage in the knee joint with the use of: autogenous transplantation of fragmented adipose tissue taken from the…
- Conditions
- Osteoarthritis, Knee, Chondral Defect, Chondromalacia, Left Knee, Chondromalacia, Right Knee
- Trial name
- NCT07110402
- Testing
- Autogenous transplant of fragmented adipose tissue taken from abdominal integuments, PRP GF (platelet-rich plasma with growth factors), Mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- eMKa MED Medical Center
Osteoarthritis, Rheumatoid Arthritis
Outcomes Study of the TM Humeral Stem Used in Primary, Total or Hemi Shoulder Arthroplasty
The objectives of this study are to obtain survival and outcome data on the Trabecular Metal Humeral Stem when used in primary, total or hemi shoulder arthroplasty.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture
- Trial name
- NCT01480453
- Testing
- Trabecular Metal Humeral Stem
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- Zimmer Biomet
Arthroplasty, Replacement, Hip, Osteoarthritis, Hip
On-Table Versus Off-Table Total Hip Arthroplasty
The Direct Anterior Approach (DAA) is a common way to perform total hip arthroplasty. There are two main techniques to perform total hip replacement through the anterior approach.
- Trial name
- NCT04831372
- Testing
- Off Table Group, On Table Group
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Carilion Clinic
Knee Osteoarthritis
Autologous Adipose Tissue Derived Mesenchymal Stem Cells Therapy for Patients With Knee Osteoarthritis
Two injections in total and 3 ml autologous adipose-tissue-derived stem cells(haMSCs) for each injection; time-points for intervention: 1) initial injection; 2) 3 weeks following initial injection.
- Trial name
- NCT01809769
- Testing
- Mesenchymal stem cells low-dose group, Mesenchymal stem cells mid-dose group, Mesenchymal stem cells high-dose group
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai AbelZeta Ltd.
Rheumatoid Arthritis, Osteoarthritis
A Study to Assess the Long-term Performance of SmartSet® HV and SmartSet® GHV Bone Cements in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of artificial hip joints implanted with two different bone cements, SmartSet® HV and SmartSet® GHV, in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872066
- Testing
- SmartSet® HV bone cement, SmartSet® GHV bone cement
- Where
- Slovakia
- Volunteers
- 243 people
- Sponsor
- DePuy International
Total Knee Arthroplasty, Osteoarthritis
A Study to Compare the NexGen CR and CR-Flex Knee Implants
The purpose of this study is to test for significant differences in functional outcomes, specifically pre-operative ROM and post-operative ROM obtained by using a NexGen CR versus a NexGen CR-Flex knee implant.
- Trial name
- NCT00761956
- Testing
- NexGen CR-Flex Fixed Bearing Knee, NexGen CR Knee
- Where
- 8 sites in United States
- Volunteers
- 189 people
- Sponsor
- Zimmer Biomet
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Investigational Testing Authorization Study
This is a prospective, single-center clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03970629
- Testing
- PERSONA Total Knee
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Knee Osteoarthritis
Implementation of Tele-Exercise for Management of Knee Osteoarthritis in Older Rural Primary Care Patients
Knee osteoarthritis (OA) is highly prevalent and a leading cause of pain that limits physical functioning in older adults. Clinical practice guidelines recommend physical exercise for managing symptoms of knee OA.
- Trial name
- NCT04706702
- Testing
- Tele-EnhanceFitness
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Washington
Osteo Arthritis Knee, Pain
Strengthening Exercises Versus Proprioception and Balance Exercises in the Treatment of Knee Osteoarthritis
The aim of the study is to investigate and compare the effect of balance and proprioception exercises with strengthening exercises on muscle strength, pain, proprioception, function and quality of life in knee osteoarthritis…
- Trial name
- NCT03893981
- Testing
- Proprioception and Balance Program, Strengthening Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University
Osteoarthritis, Knee
Safety and Efficacy of the Journey II BCS Total Knee System
Assess the safety and efficacy of the JOURNEY II BCS Total Knee System in subjects with degenerative knee disease requiring primary total knee replacement.
- Trial name
- NIMBLE (NCT01705067)
- Testing
- TKA with Journey II BCS Total Knee System
- Where
- 12 sites in United States
- Volunteers
- 209 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis
Efficacy of 3 Weekly Injections of Hyaluronate in Patients With Ankle Osteoarthritis
The aim of this study was to investigate the efficacy and safety of three weekly intraarticular injections of Hyaluronate (HA) in patients with unilateral ankle Osteoarthritis (OA).
- Trial name
- NCT00918736
- Testing
- sodium hyaluronate
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Knee Osteoarthritis
Auriculotherapy for Osteoarthritis Knee
Osteoarthritis (OA) is the most common form of arthritis in Hong Kong and a prevalent condition in the ageing population. With disease progression, some clients may develop severe pain and profound limitations in ambulation…
- Trial name
- NCT02352636
- Testing
- magnetotherapy, laser auriculotherapy
- Where
- 2 sites in Hong Kong
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Osteoarthritis, Knee
Study of Patient Outcomes 5 Years After Partial Knee Replacement
The study seeks to evaluate the condition of patients 5 years after having undergone partial knee replacement for localized osteoarthritis of the knee.
- Trial name
- NCT01620892
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Athens Orthopedic Clinic, P.A.
Sacroiliac Joint Arthritis
Platelet-rich Plasma in the Sacroiliac Joint
This is a double-blinded study where the injecting physicians and the patients will not know which arm they are randomized to. Each participant will be followed up for 6 months following the injection, and will have in office…
- Trial name
- NCT03744234
- Testing
- PRP, Steroid Injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery
First-in-human Single Ascending Dose Study of LNA043 in Patients Scheduled for Total Knee Replacement
This study is designed to evaluate the safety and tolerability of ascending single doses of LNA043 given intra-articularly into the human knee joint prior to its removal at total knee replacement surgery.
- Trial name
- NCT02491281
- Testing
- LNA043
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Novartis Pharmaceuticals
Hand Osteoarthritis
Happy Hands E-self-management Pilot Study
This pilot study will assess usability of a e-self-management program for patients with hand osteoarthritis through the Happy Hands app. People with hand osteoarthritis will be recruited for the study.
- Trial name
- NCT05150171
- Testing
- e-self-management intervention
- Where
- 2 sites in Norway
- Volunteers
- 72 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis
Clinical Investigation of Sensovisc Sterile Sodium Hyaluronate Gel
This clinical investigation aims to investigate the safety and performance of Sensovisc.Sensovisc is used to reduce osteoarthritis related pain in the joints by supporting synovial fluid by intra-articular injection and allowing…
- Trial name
- NCT07232199
- Testing
- SV-3-75: Sterile Sodium Hyaluronate Gel-3 mL Prefilled Syringe (2.5%)
- Volunteers
- 25 people
- Sponsor
- Ankara City Hospital Bilkent
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Electrochemical Behavior of Biomedical Alloys Exposed to Human Synovial Fluid
Biomedical implant metals are reactive when in contact with body fluids. Some reactions may adverse the biocompatibility character of the material and should be studied.
- Trial name
- NCT04027231
- Testing
- analysis of the synovial fluid
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Brigitte Jolles, MD
Knee Arthritis, Osteoarthritis
Muscle Recovery After Total Knee Arthroplasty
Total knee arthroplasty (TKA) surgery is a common procedure performed to reduce pain, improve function, and enhance the quality of life in patients with end-stage knee osteoarthritis.
- Trial name
- NCT06096792
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Osteoarthritis
A Randomized Control Trial to Assess Early Clinical and Functional Outcome of the ROCC and LCS Total Knee Implant Designs
This is a prospective Randomised Control Trial to compare the Early Clinical and Functional Outcome of the ROCC and LCS total knee arthroplasty implant designs.
- Trial name
- NCT00755144
- Testing
- LCS Knee, ROCC Knee
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
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