Clinical trials: Osteoarthritis Arthritis
Osteoarthritis, Knee
The Difference Between Rehabilitation With or Without Strength Training After Total Knee Replacement
Background and purpose: In the early phase after a total knee replacement (TKA), patients experience a decrease in leg muscle strength with up to about 80%.
- Trial name
- TKA (NCT01351831)
- Testing
- Rehabilitation with strength training, Rehabilitation without strength training
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Knee Osteoarthritis
Impact of Volunteerism in the Acute Setting
Rehabilitation, with a particular emphasis on physiotherapy and exercise, is widely promoted and strongly recommended after total knee replacement (TKR).
- Trial name
- NCT04063553
- Testing
- Volunteers Service, Exercise brochure
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Tan Tock Seng Hospital
Knee Osteoarthritis, Osteoarthritis, Knee
Autologous Conditioned Serum: Functional and Clinical Results
The purpose of this study was to investigate the potential ability of autologous conditioned serum (ACS) to decrease the pain and improve the joint functionality in patients affected by knee osteoarthritis (OA).
- Conditions
- Knee Osteoarthritis, Osteoarthritis, Knee, Cartilage Degeneration
- Trial name
- NCT03850080
- Testing
- Autologous Conditioned Serum
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Ospedale San Raffaele
Arthroplasty, Replacement
Walking Stick Exercise in Patients Underwent Total Knee Arthroplasty
The purpose of this study is to examine whether the effect of "hiking poles exercise" on lower extremity muscular strength, knee range of motion, and quality of life in elderly patients underwent total knee arthroplasty
- Conditions
- Arthroplasty, Replacement, Knee Osteoarthritis
- Trial name
- NCT05030662
- Testing
- Walking stick exercise
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Osteoarthritis Trapezial-metacarpal Joint
The Role of Extracorporeal Shock Wave Therapy in the Treatment of Trapezial-Metacarpal Osteoarthritis. A Double Blind Randomized Controlled Study.
Evaluate if extracorporeal shock wave therapy is more effective than sham treatment in patients with trapezial-metacarpal osteoarthritis in pain relief and functional improvement.
- Trial name
- NCT01783262
- Testing
- Extracorporeal shock wave therapy STORZ MEDICAL Modulith SLK
- Where
- Italy
- Sponsor
- University of Roma La Sapienza
Osteoarthritis
Effect of Kinesio Taping and Sham Taping in Knee Osteoarthritis
The prevalence of knee osteoarthritis has been increasing in recent decades as the number of obese people has increased. Various interventions are used to improve the functional condition of patients, but it is still not clear…
- Trial name
- OA (NCT05320562)
- Testing
- Kinesio taping
- Where
- Lithuania
- Volunteers
- 30 people
- Sponsor
- Lithuanian Sports University
Osteoarthritis (OA) of the Knee
The Efficacy of Transcutaneous Pulsed Radiofrequency Acupuncture for Knee Osteoarthritis
Efficacy of transcutaneous acupoint pulsed radiofrequency with rehabilitation for knee osteoarthritis.
- Trial name
- NCT06702046
- Testing
- transcutaneous pulsed radiofrequency acupuncture
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Knee Osteoarthritis
Evaluation of the Evolution of Biological and Imaging Markers of Bone and Cartilage Degradation in Patients With Knee Osteoarthritis Receiving Intra-articular Injections of a Hyaluronan Derivative HYMOVIS®
This pilot study MOKHA is aimed to evaluate the beneficial effect of HYMOVIS® on cartilage of patients suffering of knee osteoarthritis as revealed by using scientifically sound, objective measurements of biological and MRI-based…
- Trial name
- MOKHA (NCT04293861)
- Testing
- HYMOVIS
- Where
- 8 sites in Belgium, France
- Volunteers
- 50 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Trapeziometacarpal (TMC) Arthrosis
Off-the-Shelf Splints Versus Occupational Therapy Splints for Treatment of Trapeziometacarpal Arthrosis
The specific aim is to compare the effectiveness of Off-the-Shelf splints and splints provided by Occupational Therapy for treatment of trapeziometacarpal (TMC) arthrosis.
- Trial name
- NCT01775670
- Testing
- Off-the-shelf splint, OT Splint
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hip Osteoarthritis, Knee Osteoarthritis
Tissue Adhesive in Hip and Knee Arthroplasty, A Cost -Effectiveness Analysis
Prolonged wound drainage after total hip or knee arthroplasty is a very undesirable complication, both from medical as patients view.
- Trial name
- NCT03183583
- Testing
- Tissue adhesive in primary Total Hip and Total Knee arthroplasty
- Where
- Netherlands
- Volunteers
- 980 people
- Sponsor
- Amphia Hospital
Hip Osteoarthritis
Comparison of Two Hydroxy-apatite Coated Hip Stems
In this study, the investigators propose to randomize 80 subjects to receive either the Avenir cementless hip stem or a competing, HA-coated hip stem (Corail, DePuy-Synthes) and follow these patients for a period of 2 years…
- Trial name
- NCT03577522
- Testing
- Avenir cementless hip stem, Corail HA-coated hip stem
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Osteoarthritis Knee
Mesenchymal Stem Cell Treatment for Primary Osteoarthritis Knee
The purpose of this study is to evaluate the safety and preliminary efficacy of autologous adipose-derived mesenchymal stem cells (ADMSCs) treatment for patients with primary osteoarthritis knee.
- Trial name
- NCT02544802
- Testing
- Adipose-Derived Mesenchymal Stem Cells
- Where
- Taiwan
- Volunteers
- 4 people
- Sponsor
- Steminent Biotherapeutics Inc.
Knee Osteoarthritis
Integrated Trunk Stabilization With Osteoarthritis Rehabilitation in Knee-Spine Syndrome
This study aims to evaluate the effects of integrating trunk stabilization exercises with conventional rehabilitation in patients with knee-spine syndrome.
- Trial name
- NCT07484594
- Testing
- Trunk Stabilization exercises with conventional Rehab, Conventional Rehabilitation
- Where
- 2 sites in Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Physical Disability, Joint Function Disorder
Mexican Initiative of Patients With Osteoarthritis and Rheumatoid Arthritis (IMPACTAR)
The purpose of this study is to evaluate quality of life, degree of disability, treatment patterns and economic impact of hand and knee Osteoarthritis and Rheumatoid Arthritis in Mexico.
- Conditions
- Physical Disability, Joint Function Disorder, Axis IV Problems Economic, Compliance Behavior
- Trial name
- IMPACTAR (NCT02124031)
- Volunteers
- 10,241 people
- Sponsor
- Iniciativa Mexicana de Pacientes con Osteoartritis y Artritis Reumatoide
Osteoarthritis, Knee
Hip Joint Mobilizations and Strength Training in Patients With Knee OA Osteoarthritis
Knee osteoarthritis has been ranked 11th highest contributor to non-fatal burdens in the world. Many research studies have discussed the relationship of hip muscle with knee joint stating that impaired hip strength can be a…
- Trial name
- NCT04769531
- Testing
- Hip Joint Mobilizations, Hip joint Muscle strength training, knee strengthening and flexibility exercises
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Dow University of Health Sciences
Knee Osteoarthritis, Pain
The Effects of Collateral Meridian Therapy for Knee Osteoarthritis Pain Management
Collateral meridian therapy (CMT) is a recently developed technique according to traditional Chinese medicine (TCM) experiences, differing from traditional Chinese acupuncture in numerous manners.
- Trial name
- NCT01532531
- Testing
- "GEMORE" Multi-Function Electrotherapy Stimulator
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taichung Armed Forces General Hospital
Knee Pain Chronic, Rheumatoid Arthritis
Cemented vs Cementless Persona Keel RCT
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
- Conditions
- Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT05630053
- Testing
- Cementless Persona Knee System, Cemented Persona Knee System
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Joint Diseases, Arthritis
A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease
The purpose of this study is to compare bowel function/constipation that occurs during tapentadol treatment with that occuring during oxycodone treatment, as measured by the frequency of spontaneous bowel movements per week.
- Conditions
- Joint Diseases, Arthritis, Osteoarthritis
- Trial name
- NCT00784277
- Testing
- oxycodone CR, oxycodone IR, Tapentadol ER (CG5503)
- Volunteers
- 597 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Osteoarthritis
Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions(DDI) Among Osteoarthritis Patients
Using a retrospective database analysis, OA patients taking at least one CYP450-metabolized opioid (codeine, fentanyl, hydrocodone, methadone, oxycodone, or tramadol) and at least one other prescription drug metabolized via the…
- Trial name
- NCT01177267
- Volunteers
- 10,000 people
- Sponsor
- NEMA Research, Inc.
Primary; Coxarthrosis
Gait Initiation and Transition From Double to Single Support in Patients With Unilateral Primary Coxarthrosis
The study consists to evaluate the impact of prosthetic surgery (PTH and RTH) on kinematic and dynamic parameters (joint torques) of the lower limbs during gait initiation in patients with primary coxarthrosis.
- Trial name
- COXAM (NCT06258369)
- Testing
- Patients with primary coxarthrosis (any stage)., Patients with primary coxarthrosis (any stage) and operated with Total Hip Prosthesis (THP)., Patients with primary coxarthrosis (any stage) and operated with RTH (Hip resurfacing).
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Lille Catholic University
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