Clinical trials: Osteoarthritis Arthritis
Osteoarthritis
A Randomized Clinical Study Comparing a Fully-Coated Cementless Stem Versus a Cemented Stem for Total Hip Replacements
The purpose of this study is to answer the question as to whether or not a fully coated cementless stem is equal to or better than a cemented stem in patients over 72 years with good bone quality.
- Trial name
- NCT00689689
- Testing
- Fully coated Prodigy stem, Cemented Endurance Stem
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Nova Scotia Health Authority
Arthroplasty, Replacement, Knee, Rehabilitation
Patient Reported Outcome Measures (PROMs) in Rehabilitation With or Without the Possible Use of a Mobile Application After Primary Knee or Hip Arthroplasty
Rehabilitation after primary knee or hip arthroplasty may include performing exercises with a physiotherapist. For patients who can work well with a computer, tablet or smartphone, it is now possible to use a mobile application…
- Conditions
- Arthroplasty, Replacement, Knee, Rehabilitation, Hip Arthrosis
- Trial name
- NCT04628468
- Testing
- moveUp, Predefined number of traditional physiotherapy sessions
- Where
- 11 sites in Belgium
- Volunteers
- 416 people
- Sponsor
- University Hospital, Ghent
Osteoarthritis
Zushima Plaster for Treating Knee Osteoarthritis
The purpose of this study is to further evaluate the clinical efficacy and safety of Zushima plaster for patients in knee osteoarthrosis post-marketing.
- Trial name
- NCT02770950
- Testing
- Zushima plaster with high dose, Zushima plaster with low dose, Indometacin Cataplasms
- Where
- China
- Volunteers
- 396 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Knee Osteoarthritis, Sleep Disturbance
Neuropathic Pain and it's Relation to Sleep Quality in Knee Osteoarthritis
The primary aim is to investigate the frequency and severity of neuropathic pain and its association with night pain in patients with knee osteoarthritis. For this purpose a progressive longitudinal study design was planned.
- Conditions
- Knee Osteoarthritis, Sleep Disturbance, Neuropathic Pain
- Trial name
- NCT06430918
- Testing
- physical examination, questionnaires and inventories
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bozyaka Training and Research Hospital
Knee Osteoarthritis
Evaluation of a Home-based NMES Therapy for Knee Osteoarthritis Pain
Evaluation of knee pain and functional mobility of knee osteoarthritis patients with a home-based neuromuscular electrical stimulation (NMES) therapy
- Trial name
- NMES (NCT04128618)
- Testing
- CyMedica e-vive NMES
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- CyMedica Orthopedics, Inc
Osteoarthritic Knee Pain, Osteo Arthritis of the Knee
Effects of High-Intensity Laser Therapy Combined With Exercise in Patients With Knee Osteoarthritis
The goal of this clinical trial was to determine whether high-intensity laser therapy (HILT) combined with exercise improves pain, physical function, and muscle strength in people with knee osteoarthritis.
- Conditions
- Osteoarthritic Knee Pain, Osteo Arthritis of the Knee, Osteoarthitis, Osteoarthritis (OA) of the Knee
- Trial name
- HILT-KOA (NCT07630259)
- Testing
- High Intensity Laser Therapy, Exercise
- Where
- Chile
- Volunteers
- 31 people
- Sponsor
- Universidad Metropolitana de Ciencias de la Educacion
Osteoarthritis
Safety Study of Thumb Orthoses in Osteoarthritis in the Base of the Thumb (BTOA)
The prevalence of digital osteoarthritis varies according to whether a radiological or clinical definition is adopted. Interventions: Thumb orthoses to be worn at night and usual care vs usual care.
- Trial name
- NCT00350896
- Testing
- Thumb orthoses
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
Prospective Randomized Study Comparing the SpheriKA® (MEDACTA) and Origin® (SYMBIOS) Prostheses During Total Knee Replacement Using the Kinematic Alignment Technique
The traditional technique for implanting a total knee prosthesis, known as mechanical alignment, does not aim to preserve the original anatomy and laxity of the knee.
- Trial name
- KAOR (NCT06603103)
- Testing
- SPHERIKA prosthesis, ORIGIN prosthesis
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Osteoarthritis, Knee
Efficacy and Safety of Celecoxib Versus Placebo in the Treatment of Patients With Osteoarthritis of the Knee Who Were Unresponsive to Naproxen and Ibuprofen
To compare the safety and efficacy of celecoxib versus placebo in the treatment of patients with knee osteoarthritis who were unresponsive to treatment with prescription strength naproxen and ibuprofen or who could not tolerate…
- Trial name
- NCT00640627
- Testing
- Celecoxib
- Where
- 30 sites in United States
- Volunteers
- 380 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Reflexology and Mulligan Mobilization for Knee Osteoarthritis
to investigate the effect of adding Reflexlogy to mulligan mobilization and the conventional treatment for patients with Osteoarthritis knees
- Trial name
- NCT06815016
- Testing
- Reflexology ,mulligan mobilization and conventional, reflexology and conventional, mulligan mobilization and conventional
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Osteoarthritis, Hip
6-month Efficacy and Safety of Synolis VA 80/160 in Hip Osteoarthritis
Multicenter, independent study of Synolis VA 80/160 over a period of 6 months
- Trial name
- NCT05829733
- Testing
- SYNOLIS VA 80/160
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- Aptissen SA
Osteoarthritis, Knee
Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain
The purpose of this study is to measure the change in pain and function with subcutaneous injections of pentosan polysulfate sodium (PPS) compared with subcutaneous injections of placebo in participants with knee osteoarthritis…
- Trial name
- NCT04809376
- Testing
- Pentosan Polysulfate Sodium twice weekly, Pentosan Polysulfate Sodium Fixed Dose, Pentosan Polysulfate Sodium once weekly
- Where
- 33 sites in United States, Australia
- Volunteers
- 602 people
- Sponsor
- Paradigm Biopharmaceuticals USA (INC)
Knee Osteoarthritis
Circuit Training on Knee Osteoarthritis Patients
Introduction: The increase in intermuscular adipose tissue (IMAT) can contribute to muscle weakness and consequently on progression of knee OA.
- Trial name
- NCT02761590
- Testing
- Circuit training protocol
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Osteoarthritis, Knee
Effects of Electrical Stimulation on Osteoarthritis of the Knee
The purpose of this study is to find out whether electrical stimulation can reduce knee pain and increase function in people with osteoarthritis of the knee.
- Trial name
- NCT00601497
- Testing
- InterX 5000
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Virginia
Osteoarthritis, Knee, Pain
The Safety and Pharmacokinetics of ASKC200 in Osteoarthritic Knee Pain
This is a multi-center, randomized, double-blind clinical trial to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ASKC200 in subjects with OA of the knees and determine the phase II recommended dose.
- Trial name
- ASKC200 (NCT06614608)
- Testing
- 5% ASKC200, 1% ASKC200
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Jiangsu Aosaikang Pharmaceutical Co., Ltd.
Hip Arthritis, Hip Osteoarthritis
Defining Optimum Cup Orientation for Hip Replacements Taking Into Account the Individual's Anatomy and Movement Patterns
The purpose of this study is to investigate and determine the optimal zone for implanting the cup component (the ball that sits in the joint socket) in a total hip replacement.
- Trial name
- NCT04633525
- Testing
- Optimum Cup Orientation
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Knee
Mesenchymal Stem Cells for The Treatment of Knee Osteoarthritis (KOA).
The clinical study with UMC119-06-05 is designed to investigate the safety in patients with mild to moderate knee osteoarthritis (KOA).
- Trial name
- NCT04893174
- Testing
- UMC119-06-05, Hyaluronic acid
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- Meridigen Biotech Co., Ltd.
Knee Osteoarthritis, Hip Osteoarthritis
Adapting Rehabilitation Delivery for Maximum Impact at Home-2 (ReDI-2)
People who live in rural areas and have hip or knee arthritis can have difficulty receiving physical therapy (PT) close to home.
- Trial name
- ReDI-2 (NCT07055113)
- Testing
- Individual-based Virtual Physical Therapy Program, Group-based Virtual Physical Therapy Program
- Where
- Canada
- Volunteers
- 270 people
- Sponsor
- University of Alberta
Pain, Inflammation
Efficacy of Tart Cherry Juice to Reduce Pain and Inflammation Among Patients With Inflammatory Osteoarthritis
The purpose of this study is to assess the effects of tart cherry juice to reduce pain and inflammation among individuals with arthritis.
- Trial name
- NCT01073982
- Testing
- tart cultivar Montmorency cherry juice
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Osteoarthritis, Knee
A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the Knee
The purpose of this single-center study is to evaluate the potential analgesic effects of a single oral dose (50 mg) of JNJ-39439335, an investigational drug being developed for the treatment of pain in patients with chronic…
- Trial name
- NCT00933582
- Volunteers
- 33 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
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