Clinical trials: Osteoarthritis Arthritis
Knee Osteoarthritis, Total Knee Arthroplasty
Open and Closed Platform Robotic-assisted Versus Conventional Total Knee Arthroplasty
REAL INTELLIGENCE™ CORI™ (CORI Surgical System) is a computer-assisted orthopedic surgical system. CORI Surgical System is designed to aid surgeons in planning and executing a procedure involving bone preparation for total knee…
- Trial name
- NCT06305065
- Testing
- KUNWU Navigation TKA procedure, CORI Surgical System TKA procedure, Conventional TKA procedure
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Knee Osteoarthritis
Effectiveness of Ultrasound Guided Adductor Canal Block on Chronic Pain in Knee Osteoarthritis
Adductor canal block has become popular as effective mean for pain relief following knee surgery.This block has not been checked in chronic pain patients.The purpose of this study is to assess the efficacy and safety of adductor…
- Trial name
- NCT02695654
- Testing
- Levobupivacaine, Clonidine
- Where
- Slovenia
- Volunteers
- 77 people
- Sponsor
- Mensur Salihovic
Knee Osteoarthritis, Arthropathy of Knee
A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Primary Total Knee Arthroplasty (TKA) Patients
This research is being done to see if the amount of an enzyme in blood (called serum mast cell tryptase) changes before and after surgery.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee, Arthrofibrosis
- Trial name
- NCT03598829
- Testing
- Tryptase, Serum test
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Mayo Clinic
Osteoarthritis, Pain Syndrome
Intra-Articular, Single-shot Injection of Hyaluronic Acid and Corticosteroids in Knee Osteoarthritis
The aim of present study is to to investigate whether the combined injection of HA and CS was superior than HA alone in the treatment of knee OA.
- Conditions
- Osteoarthritis, Pain Syndrome, Intra-articular Injection
- Trial name
- NCT03047096
- Testing
- hyaluronic acid, hyaluronic acid and corticosteroids
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhongda Hospital
Knee Osteoarthritis
Prescribed Knee Brace Treatments for Osteoarthritis of the Knee (Knee OA)
The study is a non-controlled retro- and prospective multi center patient registry study. Subjects will be given a study ID number assigned at first brace fitting after consenting to partake.
- Trial name
- NCT04651673
- Testing
- This is a non interventional registry
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Össur Iceland ehf
Gonarthrosis
Therapeutic Effects of Kinesiotape in the Management of Gonarthrosis
This randomized controlled trial evaluated the effectiveness of kinesiotaping in addition to exercise for patients with knee osteoarthritis (gonarthrosis).
- Trial name
- NCT07124169
- Testing
- Kinesiotape + home exercise, Home exercise
- Volunteers
- 38 people
- Sponsor
- Fenerbahce University
Anterior Cruciate Ligament Rupture, Osteoarthritis, Knee
A Cohort Study of Non-surgical Treatment and Exercise Rehabilitation in Patients With Anterior Cruciate Ligament Rupture
This clinical trial compared the prognosis of surgical and non-surgical treatment in patients with complete anterior cruciate ligament rupture
- Trial name
- NCT05403905
- Testing
- non surgical treatment, surgical treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Meniscus Lesion
Sterile Allogeneic Spongioflex® Allograft as Partial Meniscal Replacement After Incomplete Meniscal Loss
The goal of this clinical trial is to learn if partial meniscal replacement can prevent or postpone total meniscal replacement, in adult patients (female/male) with partial meniscal loss.
- Trial name
- NCT06376422
- Testing
- Spongioflex®, non-operated
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Sven Behrendt
Osteoarthritis, Arthritis, Rheumatoid
Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis
Over 100 million Americans report chronic pain. One of the most common causes of chronic pain is osteoarthritis (OA). OA is attributable to "wear and tear," but reasons for pain are complex.
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Arthritis, Psoriatic
- Trial name
- NCT04115020
- Testing
- Naltrexone
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Arthropathy Shoulder, Shoulder Pain
Comparing the Outcome of Cemented All-Polyethylene Pegged vs. Keeled Components Through a Subscapularis Tenotomy or a Subscapularis Peel
Participants who choose to participate in this study, will either have their tendon repaired to tendon, so-called tenotomy repair, or tendon repaired to bone, so-called peel repair.
- Conditions
- Arthropathy Shoulder, Shoulder Pain, Shoulder Osteoarthritis, Shoulder Arthritis
- Trial name
- NCT03735173
- Testing
- ReUnion TSA, pegged design, ReUnion TSA, keeled design
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis
Regenerative Medicine of Articular Cartilage: Characterization and Comparison of Chondrogenic Potential and Immunomodulatory Adult Mesenchymal Stem Cells
Articular cartilage can be the seat of many diseases including osteoarthritis and traumatic defaults. The cartilage has no intrinsic ability to repair resulting at long term in function loss in the joints.
- Trial name
- ARTHROSTEM (NCT01879046)
- Testing
- arthroplasty
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Nantes University Hospital
Hip Osteoarthritis
Relationship of Radiographic Findings With Pain, Function, Physical Performance and Balance
The objective of this investigation was to examine the correlation between radiographic findings and clinical outcomes, including pain, functional ability, physical performance, and balance parameters, in patients diagnosed with…
- Trial name
- NCT07186374
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Artvin Coruh University
Knee Osteoarthristis
Neuromuscular Facilitation Protocol on Pain, Range and Function in KOA
An individual can suffer from knee osteoarthritis, which is a degenerative condition, and while standard physical therapy can assist in some way, improved joint mechanics and decreased functional limitations can be achieved…
- Trial name
- NCT07872280
- Testing
- Standard physical therapy, Neuromuscular Facilitation Protocol
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Addressing Patients' Expectations of Total Hip Arthroplasty in a Randomized Trial
The goals of this study are to develop and test an educational intervention to address patients' expectations of long-term outcomes of total hip arthroplasty.
- Trial name
- NCT00198003
- Testing
- Educational program to address patients' expectations
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis Shoulder
Prophylactic Conjoint Tendon Lengthening During Reverse Shoulder Arthroplasty Outcomes
Some patients may experience persistent pain in the front of their shoulder after reverse shoulder replacement. One of the possible reasons for this is that the surgery causes a change in the alignment of the shoulder joint…
- Trial name
- NCT06729983
- Testing
- Prophylactic Conjoint Tendon Lengthening, Standard Reverse Shoulder Arthroplasty
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Nickolas Garbis
Osteoarthritis
Study of Cartilage Relaxometry and Physical Activity in Osteoarthritis
This study is the radiological component of an earlier registered trial under the title: Efficacy of Exercise on Physical Function and Cartilage Health in Patients With Knee Osteoarthritis.
- Trial name
- NCT01797679
- Testing
- Strength Training, Aerobic Exercise
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Osteoarthritis, Arthritis
Negative Work Exercise for the Treatment of Knee Arthritis
The purpose of this study is to develop a negative work exercise regimen as an intervention for posttraumatic osteoarthritis (PTOA).
- Trial name
- PTOA-ECC (NCT02098096)
- Testing
- Negative Work, Stretching
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
Arthritis Knee
Comparing Pain and Kinematic Outcomes of Two Gait-Modifying Shoe Interventions
This study involves the use of a newly designed shoe device for knee arthritis patients that may help reduce knee pain and improve function.
- Trial name
- NCT03760380
- Testing
- Sole 1 - Neutral, Sole 1 - Offset, Sole 2 - Neutral
- Sponsor
- University of Florida
Osteoarthritis
SMC021A - Absorption, Efficacy and Tolerance in Patients With Osteoarthritis. A Placebo-Controlled 14-Days Study
The purpose of this study is to expose patients with OA to calcitonin and to determine plasma calcitonin levels after administration of 0.6 mg and 0.8 mg oral calcitonin.
- Trial name
- NCT00486369
- Testing
- Oral salmon calcitonin
- Where
- Denmark
- Sponsor
- Nordic Bioscience A/S
Osteoarthritis
Home Telerehabilitation for Deconditioned Older Adults
The purpose of this study is to develop a home exercise program for patients 60 years of age and over who are deconditioned following their discharge from the hospital, or recruited from GLA outpatient clinics.
- Trial name
- NCT00386256
- Testing
- Health Buddy, Home telehealth technology, Telephone counseling
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- US Department of Veterans Affairs
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