Clinical trials: Osteoarthritis Generalized
Osteoarthritis
Safety of Lumiracoxib in Patients With Osteoarthritis
This safety study evaluated the incidence of gastrointestinal adverse events and edema in patients with osteoarthritis treated with lumiracoxib and rofecoxib as comparator
- Trial name
- NCT00637949
- Testing
- lumiracoxib, rofecoxib
- Volunteers
- 309 people
- Sponsor
- Novartis
Primary Osteoarthritis of Hip Nos, Secondary Osteoarthritis of Hip
Randomized Controlled Study Comparing a Short Stem Hip Prosthesis With a Stem of Standard Length
80 patients eligible for a total hip replacement (THR) mainly due to primary osteoarthritis were recruited from the waiting list for hip arthroplasty at a university hospital in Sweden.
- Trial name
- NCT02983526
- Testing
- Total hip replacement (2 different designs)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johan Karrholm
Primary Osteoarthritis of Knee Nos
All Ligaments Left In Knee Arthroplasty Trial
Compare the clinical and patient reported outcomes of the Vanguard XP Knee System to the Vanguard CR Knee System in patients with antero-medial osteoarthritis of the knee with an intact anterior cruciate ligament.
- Trial name
- ALLIKAT (NCT03302013)
- Testing
- Vanguard XP Bi-cruciate Retaining Knee Replacement System, Vanguard CR Single Cruciate Retaining Knee System
- Where
- 4 sites in United Kingdom
- Volunteers
- 260 people
- Sponsor
- University of Oxford
Unilateral Primary Osteoarthritis of Knee
Assessment of Recovery After Adductor Canal Block Analgesia in Unilateral Prosthetic Knee Surgery
The purpose of the study is post-operative recovery from prosthetic knee surgery will be assessed by the proportion of patients entering the Accelerated Rehabilitation After Surgery program eligible for discharge from hospital at…
- Trial name
- IPACKNEE (NCT05715645)
- Testing
- Unilateral prosthetic knee surgery, Analgesia
- Where
- France
- Volunteers
- 130 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anesthesia, Hip Osteoarthritis
The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Postoperative recovery is always worrisome to the elder patients undergoing Total Hip Replacement (THR). Peripheral Nerve Blocks (PNBs), lumbar plexus block combined with sciatic nerve blocks, may be alterative anaesthesia style…
- Trial name
- NCT01782612
- Testing
- Multimodal analgesic techniques, Total uni-Hip Replacement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Junle Liu
Primary Osteoarthritis Requiring Total Hip Replacement
Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA)
Postoperative pain following total hip arthroplasty (THA) (1) is often considered moderate to severe and can therefore influence the postoperative course of event and result in delayed postoperative mobilization and prolonged…
- Trial name
- HÖFTPLASTIK (NCT01281891)
- Testing
- LIA, I/T morphine
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Örebro County
Knee Arthritis, Osteoarthritis, Osteo Arthritis of the Knee
Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis
The purpose of this cross-sectional, observational study is to evaluate the relationship between quadriceps muscle quality-specifically muscle echogenicity and thickness change during isometric contraction-and clinical outcomes…
- Trial name
- NCT07541274
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Osteoarthritis of the Knee
A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee
The primary purpose of the study is to evaluate the change from baseline after 4 weeks of topical administration of TV-45070 (4% and 8% ointment) compared with placebo for the relief of symptoms of primary OA affecting a single…
- Trial name
- NCT02068599
- Testing
- TV-45070
- Where
- 42 sites in United States
- Volunteers
- 389 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Osteoarthritis of the Knee
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee
To compare the analgesic efficacy and safety of ABT-652 administered twice daily (BID) to placebo in subjects with osteoarthritis (OA) of the knee.
- Trial name
- NCT01207115
- Testing
- ABT-652, Naproxen
- Where
- 38 sites in United States, Australia and 3 more
- Volunteers
- 322 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Osteoarthritis
DePuy Global Unite Shoulder System
To collect medium to long-term survivorship implant outcomes on the DePuy Global Unite Shoulder System
- Trial name
- NCT02412397
- Testing
- Total Shoulder Arthroplasty
- Volunteers
- 80 people
- Sponsor
- Rothman Institute Orthopaedics
Primary Osteoarthritis, Unspecified Shoulder
Effective Pain Management of Interscalene Blocks During Shoulder Surgery
Shoulder replacement surgery is recognized as having the potential to cause a considerable amount of postoperative pain. Adequate management of pain after surgery is necessary not only to improve the patient's wellbeing but also…
- Trial name
- NCT02267044
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- TriHealth Inc.
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Primary Osteoarthritis, Secondary Osteoarthritis
NANOS Neck Preserving Hip Stem
The objective of this study is to determine the long-term safety and effectiveness of the NANOS neck preserving stem in terms of radiographic and clinical performance as well as short-, mid- and long-term survivorship
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Dysplasia Osteoarthritis, Avascular Femoral Neck Necrosis
- Trial name
- NANOS (NCT04036279)
- Testing
- Total Hip Arthroplasty
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 130 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System FR
This is a post-marketing surveillance on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT05926622
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Osteoarthritis of Knee
Clinical Study of Non-inferiority With Participants Diagnosed With Primary Knee OA (GLACIAL)
This phase III clinical study will be conducted in Brazilian research sites. It will be included in the study 314 participants diagnosed with primary knee OA according to the classification criteria of the ACR.
- Trial name
- GLACIAL (NCT02830919)
- Testing
- Glucosamine and chondroitin sulfate combination (Eurofarma), Glucosamine and chondroitin sulfate combination (Zodic)
- Where
- 4 sites in Brazil
- Volunteers
- 627 people
- Sponsor
- Eurofarma Laboratorios S.A.