Clinical trials: Osteoarthritis Hand
Arthrosis of Hand
DIGItal Cohort Osteoarthritis Design
Introduction Osteoarthritis is a chronic disease characterized by a progressive degradation of articular cartilage. Hand OA involves symptomatically more than 1 million of subjects in France (i.e., painful or with functional…
- Trial name
- DIGICOD (NCT01831570)
- Testing
- GENETIC and radiographs
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hand Osteoarthritis
Pulsed Radiofrequency Therapy for Hand OsteoArthritis Pain
Different types of pain may be present in patients with hand osteoarthritis, including nociceptive pain and non-nociceptive pain. This makes adequate pain treatment difficult, and thus new treatment options are needed.
- Trial name
- PROAP (NCT05217979)
- Testing
- Transcutaneous pulsed radiofrequency
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Osteoarthritis
Hand Ultrasonography: Clinical and Functional Correlation in Symptomatic Osteoarthritis (OA)
Objective: To evaluate the correlation / association between inflammatory ultrasonography findings and clinical /functional assessment in symptomatic hand OA interphalangeal joints (IP).
- Trial name
- NCT02324192
- Testing
- Ultrasonography
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Knee Osteoarthritis
The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Osteoarthritis (OA) is the most common form of chronic degenerative joint disease, as well as the main cause of pain and disability in older persons worldwide.
- Trial name
- NCT02917356
- Testing
- Spiritual laying on of hands (SP), Non-spiritual Laying on of Hands, Control group
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Federal University of Juiz de Fora
Hand Osteoarthritis
Can we Use Estrogen-containing Therapy to Improve Pain in Women After Menopause With Hand Osteoarthritis?
Post-menopausal women aged 40-65 with symptomatic hand osteoarthritis are invited to take part in this feasibility study. The study's aim is to investigate whether it is acceptable to women with painful hand OA to take an…
- Trial name
- HOPE-e (NCT04036929)
- Testing
- Estrogen-bazedoxifene
- Where
- 3 sites in United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Oxford
Osteoarthritis in the Carpometacarpal (CMC) Joint
Occupational Therapy and Surgery in Carpometacarpal Osteoarthritis
The purpose of the study is to investigate if occupational therapy may delay or prevent the need for surgery in patients with carpometacarpal(CMC) osteoarthritis (OA) who are scheduled for surgery in the CMC-joint.
- Trial name
- NCT01794754
- Testing
- Care as usual, Occupational therapy
- Where
- 4 sites in Norway
- Volunteers
- 180 people
- Sponsor
- National Resource Center for Rehabilitation in Rheumatology
Thumb Carpometacarpal Joint Osteoarthritis
Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
Arthritis of the base of the thumb is a common debilitating problem. It is believed that laxity (loosening) of the joint leads to worsening arthritis in this joint.
- Trial name
- NCT00685880
- Testing
- Prolotherapy (10% dextrose solution), Betamethasone
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Thumb Osteoarthritis, CMC
3D-Printed Hand Orthosis Versus Thermoplastic Orthosis
This study will investigate the effectiveness of 3D-printed splints for treating thumb osteoarthritis (CMC OA). These splints are made by Occupational Therapists and Physical Therapists out of low-temperature plastic and formed…
- Conditions
- Thumb Osteoarthritis, CMC, Splints
- Trial name
- NCT05896410
- Testing
- splint (orthosis)
- Volunteers
- 10 people
- Sponsor
- Western University, Canada
Knee Osteoarthritis
Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA
Knee osteoarthritis is a debilitating disease that can cause severe knee pain and significant limitations to patients' activities of daily living.
- Trial name
- NCT05629715
- Testing
- ROSA Knee System, KneeAlign Computer Assisted Navigation System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Hand Osteoarthritis
Water-filtered Infrared-A Radiation in Patients With Hand Osteoarthritis
The aim of this clinical trial is to evaluate the effects of water-filtered Infrared-A radiation on patients suffering from hand osteoarthritis.
- Trial name
- NCT06329219
- Testing
- water-filtered Infrared-A radiation
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Rheumatoid Arthritis (RA) and Osteoarthritis (OA)
Serum IL-17 Correlated With Inflammatory Changes in Osteoarthritis and Rheumatoid Arthritis
The total number of the included subjects was 120 in 3 equal groups (RA, OA and control). All subject was subjected to serum IL17 level measurement.
- Trial name
- NCT04474912
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hand Osteoarthritis
Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis
The aim of this study is to compare the effect of Whale and Colditz static orthosis on pain and functional abilities of hand in thumb carpometacarpal osteoarthritis as a unique treatment.
- Trial name
- NCT02780999
- Testing
- Whale orthosis, Colditz orthosis
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Osteoarthritis Hand
Use of Allograft Adipose Matrix for Small Joint Arthritis of the Hand
The purpose the research is to evaluate the safety and efficacy of injection of adipose allograft matrix (AAM) to the small joints of the hand for treatment of early stage osteoarthritis.
- Trial name
- NCT05747469
- Testing
- local anaesthetic injection, Human Adipose Allograft
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Osteoarthritis, Osteoarthritis Finger
Effects of Using Custom Photobiomodulation Therapy for the Treatment of Osteoarthritis of the Fingers and Rhizarthrosis
Osteoarthrosis (OA), a multifactorial degenerative process, is responsible for joint pain and functional limitation. In the hand, more specifically in the proximal and distal interphalangeal joints of the fingers, it is one of…
- Conditions
- Osteoarthritis, Osteoarthritis Finger, Osteoarthritis Hand, Osteoarthritis Both Hands
- Trial name
- NCT05041231
- Testing
- Photobiomodulation therapy (PBT)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Vita Care
Osteoarthritis of the Hands
The Analgesic Activity of a Topical Formulation in Patients With Osteoarthritis of the Hands
Osteoarthritis (OA) affects over 30 million people in the United States and represents our nation's leading cause of disability.
- Trial name
- NCT02485145
- Testing
- A/B, B/A
- Volunteers
- 40 people
- Sponsor
- Transdermal Therapeutics, Inc.
Inflammatory Arthritis, Rheumatoid Arthritis
C-GLOVES: the Effectiveness of Compression Gloves in Arthritis
This is a collaborative study with 11 Occupational Therapy (OT) departments in North-West England. The OTs provide arthritis gloves to 25% of out-patients with inflammatory, rheumatoid and osteoarthritis.
- Conditions
- Inflammatory Arthritis, Rheumatoid Arthritis, Hand Osteoarthritis
- Trial name
- C-GLOVES (NCT01874067)
- Testing
- Arthritis glove
- Where
- 5 sites in United Kingdom
- Volunteers
- 75 people
- Sponsor
- University of Salford
Osteoarthritis of the Hand
Compassionate Use of Pennsaid Topical Lotion (Diclofenac) in Osteo or Rheumatoid Arthritis
This was a compassionate use, open treatment safety study of Pennsaid topical lotion (diclofenac) for osteo or rheumatoid arthritis.
- Trial name
- NCT01579890
- Testing
- Diclofenac
- Sponsor
- Mallinckrodt
Hands Osteoarthritis
Corticosteroid Intra-articular Injection in Hands Osteoarthritis
Objective - to evaluate the effectiveness and tolerance of intra-articular injections (IAI) of hexacetonide triamcinolone (HT) for the treatment of osteoarthritis (OA) in interphalangeal joints.
- Trial name
- NCT02102620
- Testing
- Intra-articular injection with corticosteroid, Intra-articular injection with lidocaine
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Osteoarthritis Hand
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of PIP Joint Osteoarthritis
The aim of this open, prospective, multicenter trial is to evaluate the use of a sterile, devitalized, processed umbilical cord amniotic membrane implant placed in joint interposition in the treatment of PIP joint osteoarthritis.
- Trial name
- NCT06034262
- Testing
- SclerFIX-IP
- Where
- 3 sites in France
- Volunteers
- 1 people
- Sponsor
- TBF Genie Tissulaire