Clinical trials: Osteoarthritis Pain
Osteoarthritis Pain
Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee
To evaluate the efficacy of ACP-044 compared with placebo in the treatment of pain associated with osteoarthritis of the knee
- Trial name
- NCT05008835
- Testing
- ACP-044 Dose A, ACP-044 Dose B
- Where
- 34 sites in United States
- Volunteers
- 61 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Osteoarthritis (OA) of the Knee
Kinesio Taping After Platelet-Rich Plasma Treatment in Individuals With Knee Osteoarthritis
This randomized controlled study evaluated whether kinesio taping provided additional benefits compared with sham taping in women with knee osteoarthritis who had received platelet-rich plasma (PRP) treatment as part of routine…
- Trial name
- NCT07773324
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Agri Ibrahim Cecen University
Osteoarthritis, Knee
Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee Pain
The purpose of this study is to evaluate the efficacy and safety of Transdermal therapeutic system (TTS) fentanyl patches (transdermal patch containing a drug that is put on the skin so the drug will enter the body through the…
- Trial name
- NCT01742897
- Testing
- TTS-fentanyl
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Janssen-Cilag Ltd.,Thailand
Knee Osteoarthritis
Wearable Sensor-based Balance Training for Patients With Knee Osteoarthritis
Knee osteoarthritis (KOA) is one of the leading causes of lower limb disability among the elderly and can cause loss of knee joint proprioception that contributes towards deterioration of postural balance.
- Trial name
- NCT02620462
- Testing
- Wearable sensor-based exercise training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Arizona
Hip Osteoarthritis
Platelet Rich Plasma Versus Corticosteroids in Hip Osteoarthritis Pain
Prospective, single-center that may go on to being multicenter, randomized trial comparing platelet rich plasma (PRP) versus corticosteroid injection for the treatment of symptoms of Hip osteoarthritis.
- Trial name
- NCT06793982
- Testing
- Platelet Rich Plasma Joint Injection, Corticosteroid Injection
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- LifeBridge Health
Osteoarthritis
Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in Men
This study will examine the effects of morphine on leuteinizing hormone, testosterone, adrenocorticotropic hormone and cortisol in men.
- Trial name
- NCT00088296
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Knee Osteoarthritis (Knee OA)
Exercise-induced Irisin in Individuals With Knee Osteoarthritis.
The goal of this prospective randomised controled study is to investigate the effect of 8-weeks brisk walking exercise on irisin levels, physical and psychosocial parameters in individuals with knee osteoarthritis, and the…
- Trial name
- Osteoarthritis (NCT06758388)
- Testing
- home exercise program, home exercise program + brisk walking exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ümmahani Kuş
Knee Osteoarthritis, Knee Arthritis
Pain Management After Adductor Canal Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial sought to evaluate the efficacy of the iPACK block with Adductor Canal Block on postoperative pain, functional recovery and NLR and PLR levels.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Arthropathy, Knee Pain Chronic
- Trial name
- NCT06086483
- Testing
- Ropivacaine 0.2% Injectable Solution, 0.9%sodium chloride
- Where
- Poland
- Volunteers
- 361 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis
Determination of Adipocytokine in Synovial Fluid of Osteoarthritis Patients
The purpose of this study is to determine the concentration of different adipocytokine (adiponectin, leptin, resistin, visfatin, osteopontin) and an inflammation classic markers as Interleukine 1 beta, tumor necrosis alfa…
- Trial name
- NCT01993342
- Testing
- arthrocentesis, ultrasonography of the knee
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Parc Taulí Hospital Universitari
Health-related Quality of Life, Pain
Outcomes During Digitally Delivered Osteoarthritis Treatment
Objectives: To examine changes in health-related quality of life (HRQL), pain and function among patients with knee or hip osteoarthritis (OA) participating in digitally delivered exercise and education treatment for up to 12 or…
- Conditions
- Health-related Quality of Life, Pain, Function, Osteoarthritis, Knee
- Trial name
- NCT05026580
- Testing
- Joint Academy exercise and education smart phone application
- Where
- Sweden
- Sponsor
- Joint Academy
Knee Osteoarthritis
Effects of Kinesio-taping in Knee Osteoarthritis Patients.
The main reason to conduct this research is to find the comparison of kinseotaping according to time duration that is 24 hours, 48 hours and 72 hours in knee osteoarthritis patients.
- Trial name
- NCT04585373
- Testing
- kinesio-taping with conventional therapy 24 hours, kinesio-taping with conventional therapy 48 hours, kinesio-taping with conventional therapy 72 hours
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Osteoarthritis of Multiple Joints
Probiotic for Pain Osteoarthritis
Many people with symptomatic Osteoarthritis (OA) report chronic joint pain, especially if those patients are older than 50 years.
- Trial name
- NCT03968770
- Testing
- Experimental group, Control group, Usual medical care
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Osteoarthritis
Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Chronic Pain in Elbow or Wrist
In patients with chronic elbow or wrist pain, the pain is controlled by conventional conservative therapy The pain reduction effect of Nexsphere-F embolization in patients who need additional treatment It is intended to…
- Trial name
- NCT06207851
- Testing
- Transcatheter Arterial Micro-Embolization
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Next Biomedical Co., Ltd.
Knee Osteoarthritis, Biofiller PRP
Evaluation of the Effect of Biofiller PRP Application on Knee Osteoarthritis
The aim of this study is to evaluate the effects of biofiller PRP on function, pain level, and femoral cartilage thickness in knee osteoarthritis: a randomized clinical study
- Conditions
- Knee Osteoarthritis, Biofiller PRP, Femoral Cartilage Thickness
- Trial name
- NCT06946056
- Testing
- Biofiller platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Osteoarthritis, Knee, Osteoarthritis, Hip
Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total joint arthroplasty, as compared to standard of care analgesia.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
- Trial name
- NCT02197273
- Testing
- Liposomal bupivacaine, Standard of care analgesia
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- OhioHealth
Osteo Arthritis Knee
High Versus Low Adductor Canal Block
The investigators will be comparing the efficacy of two different techniques for performing an adductor canal block to the saphenous nerve as a part of the multimodal pain control regimen for total knee arthroplasty.
- Trial name
- NCT04155983
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Carilion Clinic
Knee Osteoarthritis, Mind-body Exercise
Tai Chi for Knee OA Pain Management: a Mechanistic Study
This study is to determine how 8-week Tai Chi intervention alters plasma endocannabinoid and its receptors in monocytes/marcrophages, plasma oxylipinds, plasma brain-derived neurotrophic factor, brain white matter…
- Trial name
- NCT04046003
- Testing
- Tai chi exercise
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Texas Tech University Health Sciences Center
Knee Osteoarthritis
Effects of α MAT Versus Steroid Injection in Knee Osteoarthritis (STα MAT-knee Study)
Knee Osteoarthritis (OA) is a common degenerative knee condition of the knee which is treated symptomatically. Knee cartilage tissue has little regenerative ability With the developments in regenerative medicine, stem cells might…
- Trial name
- NCT04230902
- Testing
- Microfragmented Adipose Tissue Transplant, Corticosteroid injection
- Where
- Lebanon
- Volunteers
- 48 people
- Sponsor
- American University of Beirut Medical Center
Osteoarthritis, Knee
An Evaluation of a Gender Specific Insole to Provide Relief From Knee Pain Due to Osteoarthritis or General Anterior Knee Pain in Male Subjects When Used in Foot Wear Over a Period of Four Weeks
The primary objective of this trial is to demonstrate the ability of a full length foam insole to provide relief from pain due to osteoarthritis of the knee or general knee pain when used in foot wear for a 4-week period of time.
- Trial name
- NCT03556787
- Testing
- BPI 1000013 (Dr Scholls Insole)
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Bayer
Knee Osteoarthritis
Radio-frequency Ablation in Knee Osteoarthritis by Three Needles Technique
The study is designed to evaluate and compare the efficacy of three needles approach as a new technique in radiofrequency neurotomy of genicular nerve versus the traditional single needle approach as a treatment of advanced knee…
- Trial name
- NCT03613610
- Testing
- Radio-frequency ablation of genicular nerves
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alaa Fouli Gaber Ebrahim
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