Clinical trials: Osteoarthritis Pain
Osteoarthritis of the Knee
Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee
Patients with knee pain due to Osteoarthritis (OA) experiencing sub-optimal pain relief from their current analgesic regimen will participate in a pilot clinical trial to evaluate the effectiveness and tolerability of the…
- Trial name
- NCT00589979
- Testing
- Lidoderm (Lidocaine 5% Patch)
- Where
- 20 sites in United States
- Volunteers
- 169 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Osteoarthritis
A RCT of Supportive Finger Tape for PIPJ Osteoarthritis
Oesteoarthritis of the joints of the finger(s) is a common problem. The first-line treatment involves pain killers taken either as tablets, gels, or patches.
- Trial name
- NCT02220374
- Testing
- Supportive Finger Tape
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Mid Yorkshire Teaching NHS Trust
Knee Osteoarthritis
The Effectiveness of Ultrasound Guided Ozone (O2-O3) Injection With Knee Osteoarthritis
Knee ostheoarthritis (KOA) is a common disabling and degenerative disease leading to painful joints, articular stiffness, and decreased function.
- Trial name
- NCT04830423
- Testing
- Medical ozone injection, steroid injection group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Knee, Osteoarthritis, Hip
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a…
- Trial name
- NCT03737149
- Testing
- mymobility with Apple Watch
- Where
- 30 sites in United States, Australia and 2 more
- Volunteers
- 6,559 people
- Sponsor
- Zimmer Biomet
Physical Fittness
Effect of Mulligan'Mobilization With Movement on Pain, Disability and Range of Motion in Patients With Knee Osteoarthritis
we tested the effect of adding the mobilization with movement to the traditional physical therapy program on pain, ROM and functional disability in patients with knee OA.
- Trial name
- NCT01756378
- Testing
- joint mobilization with movement, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Osteoarthritis, Knee
Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the Knee
The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics of FX005 for the treatment of pain in patients with osteoarthritis of the knee.
- Trial name
- NCT01291914
- Testing
- FX005
- Where
- 13 sites in Austria, Canada and 2 more
- Volunteers
- 140 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Ulcer
Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450216
- Testing
- Ibuprofen/famotidine, Ibuprofen
- Volunteers
- 906 people
- Sponsor
- Amgen
Primary Total Knee Arthroplasty, Intraosseous Morphine Injection
Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty
Study investigators propose to investigate if a bony injection of pain medication during a knee replacement will help pain levels following primary knee replacement surgery. To investigate this, 86 patients will be enrolled.
- Conditions
- Primary Total Knee Arthroplasty, Intraosseous Morphine Injection, Knee Osteoarthritis
- Trial name
- NCT06716749
- Testing
- Morphine, Vancomycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carilion Clinic
Primary Gonarthrosis, Bilateral, Knee Osteoarthritis
Association Between Sagittal Patellar Offset and Anterior Knee Pain in Total Knee Arthroplasty
The aim of this study to evaluate whether the position of the sagittal patellar offset is a predictive factor for anterior knee pain in subjects having undergone bilateral multiradius total knee replacement.
- Conditions
- Primary Gonarthrosis, Bilateral, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT04353440
- Volunteers
- 80 people
- Sponsor
- Bezmialem Vakif University
Knee Osteoarthritis
Self Transcranial Direct Current Stimulation and Mindfulness-based Meditation for Pain in Older Adults With Knee Osteoarthritis
The purpose of this study is to determine the feasibility and preliminary efficacy of a two-week self tDCS and mindfulness-based meditation for pain in older adults with knee osteoarthritis (OA).
- Trial name
- NCT03747640
- Testing
- Self Transcranial Direct Current Stimulation (tDCS), mindfulness-based meditation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Femoro Acetabular Impingement
HAFAI Cohort 5 Year Follow up of Patients With Femoroacetabular Impingement Undergoing Hip Arthroscopy
Patients included in the HAFAI cohort will be invited for 5 year follow up.
- Trial name
- NCT04590924
- Testing
- Hip arthroscopy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Horsens Hospital
Knee Osteoarthritis, Energy Transfer Capacitative and Resistive Therapy
Efficacy of TECAR Therapy in Patients With Knee Osteoarthritis
Objective: The aim of the present study was to investigate the treatment efficacy of TECAR therapy, a modern application that has been increasingly used in recent years, compared to conventional physical therapy applications in…
- Trial name
- NCT06418360
- Testing
- TECAR, conventional physical therapy; Transcutaneous Electrical Nerve Stimulation, hotpack
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Arthritis, Osteoarthritis
Role of ASICs in Human Inflammatory Pain
In recent years, ion channels have emerged as new therapeutic targets for pain. Among these channels, ASICs (Acid Sensing Ion Channels) are of particular interest because they are directly activated by extracellular acidity…
- Conditions
- Arthritis, Osteoarthritis, Chondrocalcinosis, Gouty Arthritis
- Trial name
- NCT01867840
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Osteoarthritis, Knee
Ultrasound-Guided Pulsed Radiofrequency In The Treatment Of Patients With Osteoarthritis Knee (USPRFGENOAK)
The purpose of this study is to determine if patients with chronic painful knee osteoarthritis experience meaningful and long-term improvement in pain, function, and analgesic use after ultrasound-guided pulsed radiofrequency of…
- Trial name
- USPRFGENOAK (NCT02915120)
- Testing
- Real Pulsed Radiofrequency
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Hospital Son Llatzer
Pain, Inflammation
Efficacy of Tart Cherry Juice to Reduce Pain and Inflammation Among Patients With Inflammatory Osteoarthritis
The purpose of this study is to assess the effects of tart cherry juice to reduce pain and inflammation among individuals with arthritis.
- Trial name
- NCT01073982
- Testing
- tart cultivar Montmorency cherry juice
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Osteoarthritis
Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
Clinical study to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma.
- Trial name
- NCT01075230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Exactech
Osteoarthritis
Efficacy of Acupuncture With Physical Therapy for Knee Osteo-Arthritis
This study will examine the efficacy of acupuncture in combination with exercise physical therapy for moderate osteoarthritis (OA) of the knee.
- Trial name
- NCT00035399
- Testing
- Acupuncture
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Knee Osteoarthritis, Older Women
Adding Group-Based Pain Neuroscience Education to a Community Exercise Program for Older Women With Knee Osteoarthritis
This pilot trial aimed to estimate preliminary clinical effects and to assess the feasibility of adding group-based pain neuroscience education (PNE) to exercise in women aged ≥60 years with medically diagnosed knee…
- Conditions
- Knee Osteoarthritis, Older Women, Pain, Disability
- Trial name
- NCT07565298
- Testing
- Pain neuroscience education (PNE), Exercise program
- Where
- Chile
- Volunteers
- 19 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Obesity, Overweight
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
This study is being done to look at the safety and effect of NNC0487-0111 in people with excess body weight and knee osteoarthritis when compared to placebo.
- Conditions
- Obesity, Overweight, Osteoarthritis, Knee
- Trial name
- AMAZE 6 (NCT07509307)
- Testing
- NNC0487-0111
- Where
- 81 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
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