Clinical trials: Osteoarthritis Pain
Lower Back Pain, Facets Joints Osteoarthritis
Safety and Efficacy of MRgFUS for the Treatment of Low Back Pain
Chronic pain affects an estimated 50 to 65 million individuals in the US, and its incidence and prevalence is steadily on the rise in correspondence with the increasing longevity of the population.
- Trial name
- NCT01232582
- Testing
- Exablate treatment
- Where
- 2 sites in Israel, United Kingdom
- Volunteers
- 50 people
- Sponsor
- InSightec
Knee Osteoarthritis
ESCAPE-pain Programme in Malaysia
The overall aim of this study is to develop an evidence based exercise programme for the management of knee osteoarthritis which is feasible and acceptable to patients and healthcare professionals in Malaysia.
- Trial name
- NCT03379623
- Testing
- ESCAPE-pain Programme
- Where
- 2 sites in Malaysia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Kamil Che Hasan
Patellofemoral Osteoarthritis
Proximal and Distal Therapeutic Approach in Pain and Lower Limb Kinematic in People With Patellofemoral Osteoarthritis
This is a crossover study that will investigate the immediate effects of a proximal therapeutic approach (SERF strap) and a distal one (foot orthoses) on knee pain intensity, global change, symptoms, ease of performance and…
- Trial name
- NCT04332900
- Testing
- Elastic hip strap, Insole
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Sao Carlos
Osteoarthritis Hip, Joint Disease
Mobilization With Movement in Patients With Osteoarthritis of the Hip
The concept of mobilization with movement, also referred to as a Mulligan mobilization, has not been studied in patients with hip osteoarthritis, subsisting questions about the possible effects in this population.
- Conditions
- Osteoarthritis Hip, Joint Disease, Musculoskeletal Diseases, Pathologic Processes
- Trial name
- MWM (NCT02390336)
- Testing
- Real mobilization-with-movement (MWM)
- Volunteers
- 40 people
- Sponsor
- Natália Maria Oliveira Campelo
Gonarthrosis
Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy
The main symptom of knee osteoarthritis, which occurs after damage to the joint cartilage with age, is pain, but this symptom often becomes chronic.
- Trial name
- NCT06914960
- Testing
- 2-point Radiofrequency Ablation, 3-point Radiofrequency Ablation, 5-point Radiofrequency Ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Bengu Turemenogullari
Osteoarthritis, Knee
Residual Pain After Successful Implant of Metaphyseal Sleeves in Total Knee Arthroplasty
: Total knee revision arthroplasty is increasing in daily practice and will become more relevant in the years to come. Bone loss is a significant challenge in total knee arthroplasty (TKA) especially in revision procedures.
- Trial name
- NCT04995679
- Testing
- Implant of metaphyseal sleeves in Total knee arthroplasty
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- University of Milan
Osteo Arthritis Knee, Obesity
Effect of Prebiotics on Function and Pain in Patients with Osteoarthritis and Obesity
The purpose of the present study is to determine if prebiotic supplementation can, through changes in the intestinal gut microbiota, lead to improvements in knee function and physical performance and reduce knee pain in adults…
- Trial name
- NCT04172688
- Testing
- Prebiotic oligofructose-enriched inulin
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Calgary
Osteo Arthritis of the Knee, Pain
The Effectiveness of BETY in Knee Osteoarthritis With Intra-Articular Injections
Osteoarthritis (OA) is the most common condition in middle-aged and elderly populations; it causes pain and physical disability and is characterized by cartilage degeneration, changes in bone tissue, inflammation of the synovial…
- Conditions
- Osteo Arthritis of the Knee, Pain, Pain Management, Exercise
- Trial name
- NCT07496203
- Testing
- BETY
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Post-traumatic Osteoarthritis of the Knee
Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Traumatic Osteoarthritis of the Knee
This study was a double-blind, randomized, parallel group, proof of concept study comparing FX006 to Kenalog®-40 (triamcinolone acetonide injectable suspension, USP) in patients with post-traumatic osteoarthritis of the knee.
- Trial name
- NCT02468583
- Testing
- FX006 32 mg, TCA IR 40 mg
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Knee Osteoarthritis
Bowen Technique and Post Isometric Relaxation in Knee Osteoarthritis Patients
The Hamstring muscles are present at the posterior surface of the thigh. The muscles start in the gluteal region and run back of the thigh and insert into the popliteal fossa.
- Trial name
- NCT05723029
- Testing
- Bowen Technique, Post Isometric Relaxation
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Effectiveness of DN With or Without Mulligan Two Leg Rotation Technique on Pain ROM and Joint Dysfunction in KO
The objective of study is to determine the effectiveness of dry needling with or without mulligan two leg rotation technique on pain, range of motion and joint dysfunction in knee osteoarthritis.
- Trial name
- NCT06739954
- Testing
- Mulligan's Two Leg Rotation technique, Dry Needling
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Superior University
Transcutaneous, Pulsed Radiofrequency
Transcutaneous Pulsed Radiofrequency Application Plus Genicular Nerve Block Versus Intraarticular Hyaluronic Acid Injection for Management of Chronic Pain in Knee Osteoarthritis.
The aim of the present study is to compare the analgesic efficacy of combined transcutaneous pulsed radiofrequency plus genicular nerve block with bupivacaine plus corticosteroid versus intraarticular Hyaluronic acid injections…
- Conditions
- Transcutaneous, Pulsed Radiofrequency, Genicular Nerve Block, Intraarticular
- Trial name
- NCT06710782
- Testing
- Hyaluronic acid, Transcutaneous pulsed radiofrequency
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Chronic Pain, Anxiety
Nu-V3 Non-Invasive Nerve Stimulation Device Trial for Chronic Pain, Anxiety, Depression, Sleeplessness
The Nu-V3 Clinical Study is a prospective, single-arm, open-label, multi-center study using the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3 (NCT05335980)
- Testing
- Nu-V3
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nu-Life Solutions
Osteoarthritis, Knee
The Comparison of Anterior Knee Pain in Patella With or Without Denervation in Medial Unicompartmental Knee Arthroplasty
the present study will conduct to assess anterior knee pain and complications after medial UKA with or without patella denervation in medial compartment arthritis and severe lateral facet patellofemoral arthritis patients.
- Trial name
- NCT03676179
- Testing
- patella denervation, patella non-denervation
- Where
- Thailand
- Volunteers
- 66 people
- Sponsor
- Ramathibodi Hospital
Knee Osteoarthritis
Evaluation of the Evolution of Biological and Imaging Markers of Bone and Cartilage Degradation in Patients With Knee Osteoarthritis Receiving Intra-articular Injections of a Hyaluronan Derivative HYMOVIS®
This pilot study MOKHA is aimed to evaluate the beneficial effect of HYMOVIS® on cartilage of patients suffering of knee osteoarthritis as revealed by using scientifically sound, objective measurements of biological and MRI-based…
- Trial name
- MOKHA (NCT04293861)
- Testing
- HYMOVIS
- Where
- 8 sites in Belgium, France
- Volunteers
- 50 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Knee Arthritis Osteoarthritis, Chronic Knee Pain
The Predictive Value of Ultrasonographic Quadriceps Muscle Parameters for Genicular Nerve Block Outcomes in Knee Osteoarthritis
The goal of this observational study is to learn whether thigh muscle structure can help predict pain relief after a genicular nerve block in people with knee osteoarthritis.
- Trial name
- NCT07781059
- Testing
- genicular nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Marmara University
Knee Osteoarthritis, Pain
Magnetotherapy Versus Microwave Combined With Exercise for Knee Osteoarthritis.
The high prevalence of knee osteoarthritis and the absence of well-defined protocols for the application of Magnetotherapy (MT), makes it necessary to investigate the effect of this therapy on patients with knee osteoarthritis.
- Trial name
- MT-MW-EX (NCT04866745)
- Testing
- Magnetotherapy plus exercise, Microwave plus exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Castilla-La Mancha
Knee Osteoarthritis
Efficacy Study of Pre-emptive Etoricoxib for Postoperative Pain and Functional Outcome in Total Knee Arthroplasty
The purpose of this study is to study the efficacy of pre-emptive etoricoxib in reducing post-operative pain and improving function outcome after a total knee arthroplasty.
- Trial name
- NCT01246362
- Testing
- Control, Etoricoxib
- Where
- Singapore
- Volunteers
- 65 people
- Sponsor
- Singapore General Hospital
Osteoarthritis
Prospective Multicenter Non-interventional Study in Patients With Knee or Hip Osteoarthritis Having a Theraflex Treatment
The main purpose of this study is to evaluate how a long-term treatment with Theraflex during 64 weeks affects pain intensity in the affected knee or hip joint, the activity in daily living, the quality of life and patient…
- Trial name
- NCT03330288
- Testing
- Theraflex, BAY 874017
- Where
- 2 sites in Russia
- Volunteers
- 1,102 people
- Sponsor
- Bayer
Osteoarthritis, Knee
A Study of LY2828360 in Patients With Osteoarthritic Knee Pain
To investigate the safety, efficacy and pharmacokinetics of single daily oral dose of LY2828360 in male and female subjects with osteoarthritic knee pain
- Trial name
- NCT01319929
- Testing
- LY2828360
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Eli Lilly and Company