Clinical trials: Osteoarthritis Pain
Osteoarthritis, Rheumatoid Arthritis
Injections of FloGraft Therapy, Autologous Stem Cells, or Platelet Rich Plasma for the Treatment of Degenerative Joint Pain
This study will assess the outcomes of three currently available regenerative treatments (FloGraft, autologous stem cell therapy, platelet rich plasma therapy) for painful degenerative conditions of the joints.
- Trial name
- NCT01978639
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Arizona Pain Specialists
Osteoarthritis, Knee
Study of Pain Catastrophizing-2 (SPAC-2)
This study experimentally manipulates pain catastrophizing in order to investigate the neural mechanisms by which pain catastrophizing influences the experience of pain in different ethnic groups among adults with knee…
- Trial name
- SPAC (NCT04805190)
- Testing
- Cognitive-Behavioral Intervention, Pain Education
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Florida
Knee Osteoarthritis, Pain
Reiki Effects on Pain, Functional Status and Holistic Well-Being in Patients With Knee Osteoarthritis
This study aimed to examine the effect of Reiki therapy on pain, functional status and holistic well-being in patients with knee osteoarthritis.
- Trial name
- NCT05665959
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara Medipol University
Knee Osteoarthritis
Descriptive Study of Knee Joint Pain During Strength Training After Total Knee Arthroplasty
Background: In the early phase after a total knee arthroplasty (TKA), patients experience multi-level weakness in the operated leg, which is caused primarily by reduced central nervous system (CNS) activation failure of the…
- Trial name
- NCT01729520
- Testing
- Knee extension strength training
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Hvidovre University Hospital
Osteoarthritis of the Knee
An Extension Study of Duloxetine in Osteoarthritis and Knee Pain (Extension of F1J-JE-HMGX, NCT02248480)
The purpose of this study is to assess the safety and efficacy of duloxetine in participants with osteoarthritis and knee pain. The study will last for 1 year.
- Trial name
- NCT02335346
- Testing
- Duloxetine
- Where
- Japan
- Volunteers
- 93 people
- Sponsor
- Eli Lilly and Company
Knee Osteoarthritis
Analgesic Effectiveness of Three Different Doses of a New Formulation of Lamaline in a Model of Painful Knee (Gonarthrosis)
This study aims to assess the analgesic effectiveness and safety of three different doses of a new formulation of Lamaline® versus Dafalgan® Codeine after 10 days administration in subjects with painful gonarthrosis
- Trial name
- NCT00264225
- Testing
- Lamaline® , 3 different doses, Dafalgan codeine
- Where
- 171 sites in France
- Sponsor
- Solvay Pharmaceuticals
Osteoarthritis
Study of FLEXISEQ® for Treatment of Osteoarthritis of the Knee in NSAID-compromised Patients
Primary Objective To substantiate the efficacy of 2.2 g FLEXISEQ® for the treatment of pain related to osteoarthritis (OA) of the knee in patients contraindicated for or with clinical intolerance to NSAIDs.
- Trial name
- OANIT (NCT02594176)
- Testing
- FLEXISEQ®
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Pro Bono Bio
Osteo Arthritis Knee, Movement Disorders
Investigation of the Effect of Movement Mobilization Concept on Sensory, Pain, Muscle Activation in Patients With Knee Osteoarthritis
Individuals with knee osteoarthritis are one of the groups most affected by musculoskeletal disorders and experience pain and mobility limitations that significantly limit their daily living activities.
- Conditions
- Osteo Arthritis Knee, Movement Disorders, Physical Disability, Knee Osteoarthritis
- Trial name
- NCT06527313
- Testing
- Movement Mobilization Concept, Exercise and Tape, Special Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istinye University
Knee Osteoarthritis, Gonarthrosis; Primary
Oral vs Intravenous Dexamethasone in Total Knee Arthroplasty
This prospective observational cohort study aims to evaluate the association between perioperative dexamethasone administration and early postoperative recovery following primary total knee arthroplasty.
- Conditions
- Knee Osteoarthritis, Gonarthrosis; Primary, Total Knee Arthroplasty
- Trial name
- TKA (NCT07442812)
- Testing
- Routine perioperative management
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Haseki Training and Research Hospital
Knee Osteoarthritis, Osteoarthritis of the Knee
Postmarketing Multicenter Study of Intra-Articular DIART ONE / EASYGO ONE for Knee Osteoarthritis
This study looked at how safe and effective a hyaluronic acid-based injection (called DIART ONE or EASYGO ONE) is for people with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Osteoarthritis of the Knee, Degenerative Joint Disease
- Trial name
- NCT06927934
- Where
- Ukraine
- Volunteers
- 55 people
- Sponsor
- Yuria-Pharm
Anterior Knee Pain
Comparison of Removing and Non-removing Patellofemoral Joint Osteophytes Following Medial Unicompartment Knee Arthroplasty
Background: Anterior knee pain (AKP) is a challenge following unicompartmental knee arthroplasty (UKA). Some surgeons remove patellofemoral joint (PFJ) osteophytes to reduce osteophyte impingement and AKP.
- Trial name
- NCT05367375
- Testing
- removing osteophyte at patellofemoral joint
- Volunteers
- 90 people
- Sponsor
- Thammasat University
Chronic Pain
The Power of Touch. Non-Invasive C-Tactile Stimulation for Chronic Osteoarthritis Pain
Osteoarthritis (OA) is a degenerative disease with a prevalence of up to 30% among adults over 45 years old. Moreover, elderly people over 60 years are more prone to develop a chronification of pain symptomatology.
- Trial name
- TouchStim (NCT06060028)
- Testing
- Interoceptive stimulation treatment with mechanical stimulation of C-LTMRs afferences
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Auxologico Italiano
Joint Disease
Post Market Clinical Follow-up Study Protocol for DYNASTY® BioFoam® Acetabular Components
Sponsor is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) components marketed in the European Union (EU) .
- Trial name
- NCT02149667
- Testing
- total hip arthroplasty implant
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- MicroPort Orthopedics Inc.
Facet Joint Pain, Back Pain
Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain
This is a Phase 2a safety and efficacy study of XT-150 in adult participants experiencing back pain due to inflammation of the facet joint, also known as facet joint osteoarthritis (FJOA), and who are eligible for intra articular…
- Conditions
- Facet Joint Pain, Back Pain, Inflammation
- Trial name
- NCT05196919
- Testing
- XT-150
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Xalud Therapeutics, Inc.
Osteoarthritis, Knee
Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA)
This prospective randomized controlled trial evaluates whether a modified J-shaped skin incision can reduce peri-incisional numbness after primary total knee arthroplasty (TKA) compared with the conventional midline skin…
- Trial name
- NCT07514598
- Testing
- Conventional Midline Incision, J-shaped Incision
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Ankle Osteoarthritis, Prostheses and Implants
Phi Angle and Antero-medial Pain in Total Ankle Replacement Follow-up
The study evaluates the relation between the rotational alignment of the talar component (phi angle) and the antero-medial ankle pain in patients underwent total ankle replacement, at least one year after surgery.
- Trial name
- NCT03772236
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Knee Osteoarthritis
The Efficacy of Interferential Current Treatment on Knee Osteoarthritis
The effects of different carrier frequencies of interferential current on pain and function in patients with knee arthrosis will be compared
- Trial name
- NCT04015323
- Testing
- Interferential current
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ege University
Osteoarthritis, Knee
Periosteal Stimulation for Knee Osteoarthritis
185 veterans with chronic knee pain and advanced knee osteoarthritis will be recruited to participate in this study designed to test the effectiveness of a special type of electrical acupuncture called periosteal stimulation…
- Trial name
- PST (NCT00865046)
- Testing
- Periosteal stimulation, Control-Periosteal Stimulation
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- US Department of Veterans Affairs
Knee Osteoarthritis
Evaluation of a Home-based NMES Therapy for Knee Osteoarthritis Pain
Evaluation of knee pain and functional mobility of knee osteoarthritis patients with a home-based neuromuscular electrical stimulation (NMES) therapy
- Trial name
- NMES (NCT04128618)
- Testing
- CyMedica e-vive NMES
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- CyMedica Orthopedics, Inc
Pain Reduction, Function Improvement
Duloxetine for Pain in Older Adults With Knee Osteoarthritis (OA)
Osteoarthritis (OA), a common disabling condition, is the commonest type of arthritis worldwide.Pain is the leading symptom and is often chronic in na.
- Trial name
- NCT01425827
- Testing
- duloxetine HCL
- Where
- Egypt
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
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