Clinical trials: Osteoarthritis Pain
Osteoarthritis, Knee, Obesity
Effects of Diet Control and Resistance Exercise Training on Obesity Adults With Knee Osteoarthritis
The purpose of this study was to investigate the effects of obesity on knee degenerative arthritis on body composition after dietary control and elastic resistance exercise; and whether persistent exercise habits and dietary…
- Conditions
- Osteoarthritis, Knee, Obesity, Diet, Healthy, Training Group, Sensitivity
- Trial name
- NCT03973463
- Testing
- Elastic knee joint movement
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Arthritis, Osteoarthritis, Osteo Arthritis of the Knee
Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis
The purpose of this cross-sectional, observational study is to evaluate the relationship between quadriceps muscle quality-specifically muscle echogenicity and thickness change during isometric contraction-and clinical outcomes…
- Trial name
- NCT07541274
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Osteoarthritis, Knee
Residual Pain After Successful Implant of Metaphyseal Sleeves in Total Knee Arthroplasty
: Total knee revision arthroplasty is increasing in daily practice and will become more relevant in the years to come. Bone loss is a significant challenge in total knee arthroplasty (TKA) especially in revision procedures.
- Trial name
- NCT04995679
- Testing
- Implant of metaphyseal sleeves in Total knee arthroplasty
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- University of Milan
Musculoskeletal Diseases, Osteoarthritis, Knee
Effect of Research Participation Versus Usual Clinical Treatment on Pain in Patients With Musculoskeletal Disorders
This study explores the effects on pain, function and illness perceptions, of participating in clinical research versus being treated with standard care in patients with musculoskeletal disorders.
- Conditions
- Musculoskeletal Diseases, Osteoarthritis, Knee, Illness Perceptions
- Trial name
- NCT03785561
- Testing
- participation in a health research study
- Where
- Denmark
- Volunteers
- 1,850 people
- Sponsor
- Frederiksberg University Hospital
Chronic Knee Pain, Osteoarthritis
Genicular Embolization Using Doxycycline Sclerotherapy
The goal of this prospective case series is to develop an alternative pain management procedure for patients who are not surgical candidates.
- Trial name
- NCT07024654
- Testing
- Doxycycline Injection
- Sponsor
- Campbell Clinic
Knee Osteoarthritis, Visual Rehabilitation
Effects of Visual and Vestibular Rehabilitation in Individuals With Knee Osteoarthritis
This study aims to investigate the effects of visual rehabilitation and vestibular rehabilitation added to conventional physiotherapy on postural stability, pain, and functional status in individuals with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Visual Rehabilitation, Vestibular Rehabilitation, Postural Stability
- Trial name
- NCT07888920
- Testing
- Conventional Physiotherapy, Visual Rehabilitation, Vestibular Rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Aydın University
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Knee Osteoarthritis, Knee Pain Chronic
Two-level ESPB in Total Knee Arthroplasty
Effect of two-level ESPB in Total Knee Arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT06470542
- Testing
- 2 x 20 ml of Ropivacaine 0.2% Injectable Solution, 2 x 20ml of Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Knee Osteoarthritis
Kinesiotaping With and Without Combined Chain Exercises in Patients With Knee Osteoarthritis
Knee osteoarthritis is a major public health issue because it causes chronic pain, reduces physical function and diminishes quality of life.
- Trial name
- NCT05334524
- Testing
- kinesiotaping with combined chain exercises, kinesiotaping
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Knee Osteoarthristis
Effect of Knee and Heel Off-Loader Brace With Non Weight Bearing Strength in Knee Osteoarthritis
The current study is a single-blinded, parallel-group pilot randomized controlled trial involving 20 participants diagnosed with knee osteoarthritis (KOA).
- Trial name
- NCT07562685
- Testing
- Knee and Heel Off-Loader Brace with NWB Strength Training, Conventional Knee Off-Loader Brace with NWB Strength Training
- Volunteers
- 20 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Knee Osteoarthritis, Sleep Disturbance
Neuropathic Pain and it's Relation to Sleep Quality in Knee Osteoarthritis
The primary aim is to investigate the frequency and severity of neuropathic pain and its association with night pain in patients with knee osteoarthritis. For this purpose a progressive longitudinal study design was planned.
- Conditions
- Knee Osteoarthritis, Sleep Disturbance, Neuropathic Pain
- Trial name
- NCT06430918
- Testing
- physical examination, questionnaires and inventories
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bozyaka Training and Research Hospital
Knee Osteoarthritis
Mulligan Rotational Movement Versus Medial Gapping Technique in Patients With Knee Osteoarthritis
Knee osteoarthritis is a progressive degenerative and non-inflammatory joint disorder. Due to the extensive use and stress placed on knee joint, it is a common site for painful disorders such as knee osteoarthritis.
- Trial name
- NCT05338840
- Testing
- MULLIGAN ROTATIONAL MOVEMENT, Medial gapping technique
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hip Osteoarthritis, Hip Arthroplasty Replacement
Post-Operative Spinal Block Duration and Pain Relief After Hip Replacement Surgery: Comparing Single-Shot Spinal Ropivacaine and Bupivacaine
This study aims to determine whether isobaric ropivacaine is more suitable than isobaric bupivacaine for spinal anesthesia in outpatient total hip arthroplasty (THA).
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Postoperative Pain After Ambulatory Surgery
- Trial name
- ROBUTHA (NCT07631091)
- Testing
- Spinal Anesthesia with Ropivacaine 15 mg (5 mg/ml), Spinal Anesthesia with Bupivacaine 11 mg (5 mg/ml)
- Volunteers
- 176 people
- Sponsor
- University of Turku
Osteoarthritis, Knee
A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain
This is a randomized, double-blind, placebo-controlled, 2-injection, 52-week study to evaluate the efficacy and safety of intra-articular injections of CNTX-4975-05 in subjects with chronic, moderate-to-severe osteoarthritis knee…
- Trial name
- NCT03660943
- Testing
- CNTX-4975-05
- Where
- 30 sites in United States
- Volunteers
- 332 people
- Sponsor
- Centrexion Therapeutics
Osteoarthritis
Brain Imaging To Examine The Effect Of Naproxen In Hand Osteoarthritis Patients
The study hypothesis is that the relief of pain in patients with osteoarthritis in the hand can be detected by a form of brain scanning that detects which parts of the brain are activated when pain is felt.
- Trial name
- NCT00830050
- Testing
- Naproxen
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Pfizer
Peripheral Neuropathies, Osteoarthritis
A Proof of Concept Study to Investigate the Effect of a New Treatment in Patient With Chronic Pain
The purpose of this clinical trial conducted in patients suffering from chronic pain is to study the relationship between individual patients' profile and their analgesic response
- Trial name
- NCT02459197
- Testing
- Heat Pain Stimuli A, Heat Pain Stimuli B, Positive Video
- Where
- 6 sites in Belgium, France
- Volunteers
- 114 people
- Sponsor
- Tools4Patient
Knee Osteoarthritis
Short Term Efficacy of High-intensity Laser Therapy in Patients With Knee Osteoarthritis
Knee osteoarthritis (KOA) is one of the most common health problems around the world. According to this, several interventions have been used to treat this group of patients including pharmacological and non-pharmacological…
- Trial name
- NCT04889885
- Testing
- High-intensity laser therapy (HILT)
- Volunteers
- 42 people
- Sponsor
- Mahidol University
Osteoarthritis
Pain Expectations in Subjects With Osteoarthritis
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat…
- Trial name
- NCT02155257
- Testing
- Modafinil, Gabapentin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Knee Osteoarthritis
A Multi-centre Study of Shoe-worn Insoles and Knee Osteoarthritis
Shoe-worn insoles (also known as orthotics) can provide symptomatic relief for people with knee osteoarthritis. However, given they act at the feet, and given that many people with knee osteoarthritis also report foot pain, it is…
- Trial name
- MULTIWEDGE (NCT06251167)
- Testing
- Lateral wedge insoles (LWIs), Lateral wedge plus custom arch support (LWAS)
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of British Columbia
Osteoarthritis, Knee
Cryotherapy Effectiveness in Individuals With End Stage Knee Osteoarthritis - a Case Series
The purpose of this case series will be to provide a detailed description of a standardized short-term cryotherapy application protocol using validated functional outcome measures in individuals with end stage KOA
- Trial name
- NCT03582644
- Testing
- Cryotherapy
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Universidade Federal de Sao Carlos
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