Clinical trials: Osteoarthritis Pain
Knee Osteoarthritis
Proprioceptive Exercises on Joint Pain and QoL Among Geriatric Patients With Knee Osteoarthritis
Knee osteoarthritis, the disease of knee joint pain caused by joint degeneration, it is the commonest joint disease and had a negative effect on geriatric patients' quality of life (QoL).
- Trial name
- NCT06574334
- Testing
- Proprioceptive exercise
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University
Post Operative Pain, Postoperative Nausea and Vomiting
Postoperative Analgesia in Hip Arthroplasty
The goal of this clinical trial is to compare the analgesic effectiveness of two blocks in hip arthroplasty. The main question it aims to answer is -Which block is more efficient? Researchers will compare the suprainguinal fascia…
- Conditions
- Post Operative Pain, Postoperative Nausea and Vomiting, Hip Osteoarthritis
- Trial name
- NCT07153575
- Testing
- suprainguinal fascia iliaca block, Pericapsular nerve group (PENG) block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Osteoarthritis
A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee
To assess the safety and tolerability of orally-administered CR845 in patients with osteoarthritis (OA) of the hip or knee. The study drug is being tested to reduce OA pain, and will be taken twice a day for two weeks, with four…
- Trial name
- NCT02524197
- Testing
- CR845 0.25 mg, CR845 0.50 mg, CR845 1 mg
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- Cara Therapeutics, Inc.
Knee Osteoarthritis
Kinesiotaping With and Without Combined Chain Exercises in Patients With Knee Osteoarthritis
Knee osteoarthritis is a major public health issue because it causes chronic pain, reduces physical function and diminishes quality of life.
- Trial name
- NCT05334524
- Testing
- kinesiotaping with combined chain exercises, kinesiotaping
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Hip Osteoarthritis, Hip Arthropathy
PENG Block for Total Hip Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the pericapsular nerve group block on postoperative rehabilitation.
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Disease, Hip Pain Chronic
- Trial name
- NCT05944380
- Testing
- Ropivacaine 0.5% Injectable Solution, 0,9% normal saline
- Where
- Poland
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Chronic Pain
Preoperative Catastrophizing Predicts Pain Outcome After Shoulder, Knee and Hip Arthroplasty
Psychologic status is associated with poor outcome after joint arthroplasty and perhaps chronic pain. To enhance the therapeutic effect of a psychologic intervention, the specific disorders or pain-related beliefs that…
- Conditions
- Osteoarthritis, Chronic Pain, Catastrophization
- Trial name
- NCT02361359
- Testing
- Psychological questionnaires
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospital Ambroise Paré Paris
Knee Osteoarthritis, Visual Rehabilitation
Effects of Visual and Vestibular Rehabilitation in Individuals With Knee Osteoarthritis
This study aims to investigate the effects of visual rehabilitation and vestibular rehabilitation added to conventional physiotherapy on postural stability, pain, and functional status in individuals with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Visual Rehabilitation, Vestibular Rehabilitation, Postural Stability
- Trial name
- NCT07888920
- Testing
- Conventional Physiotherapy, Visual Rehabilitation, Vestibular Rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Aydın University
Hand Osteoarthritis
Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Patients With Hand Osteoarthritis
Hand osteoarthritis (HOA) which affects the interphalangeal joints and the metacarpophalangeal of the thumb is a common disease, the prevalence of which being about 30 % of the population over than 70.
- Trial name
- TIDOA (NCT02477059)
- Testing
- tocilizumab, saline solution
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Arthritis, Arthritis (Knee)
Kinematic Alignment in Total Knee Arthroplasty - a Double-blind Randomised Controlled Trial Between Robotic and Caliper-based Techniques
Knee replacement surgery is a surgery designed to treat severe arthritis of the knee. However, as many as 20% of patients are not satisfied with the results of their surgery.
- Conditions
- Arthritis, Arthritis (Knee), Osteoarthritis, Osteoarthritis Knee Pain
- Trial name
- NCT06709703
- Testing
- Kinematic aligned total knee replacement
- Volunteers
- 200 people
- Sponsor
- Université de Sherbrooke
Osteoarthritis of the Knee
A Randomized, Controlled Study to Evaluate Efficacy and Safety of Intra-articular Ampion for Osteoarthritis Pain in Knee
This study will evaluate the efficacy of an Intra-Articular Injection of Ampion™ in Adults with pain due to osteoarthritis of the knee.
- Trial name
- NCT02024529
- Testing
- 4 mL injection of Ampion
- Volunteers
- 538 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Knee Osteoarthritis
Effectiveness Study of the Ivivi SofPulse for Pain Amelioration in Adults With Mild to Moderate Knee Osteoarthritis
The purpose of this study is to determine the effectiveness of non-thermal Pulsed Radio Frequency (PRF) treatment with the Ivivi SofPulse for amelioration of knee pain in patients with mild to moderate Osteoarthritis and to…
- Trial name
- NCT01457742
- Testing
- Ivivi SofPulse
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Amp Orthopedics, Inc.
Osteo Arthritis Knee and Hip, Low Back Pain
COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL
This study aims to find out which lifestyle approach works best for people with chronic musculoskeletal pain (such as low back pain or hip/knee osteoarthritis) who also have poor sleep.
- Conditions
- Osteo Arthritis Knee and Hip, Low Back Pain, Insomnia
- Trial name
- SLEEPFIT (NCT07532070)
- Testing
- Aerobic physical activity, CBT-I, Combined aerobic physical activity and CBT-I
- Where
- 4 sites in United States, Australia
- Volunteers
- 384 people
- Sponsor
- University of Sydney
Osteoarthritis, Chronic Pain
Physiological Impact of Different Types of Osteoarthritis Education.
In this study, the investigators are comparing two types of education for older adults with knee osteoarthritis: standard biomedical education focusing on the disease process, and a newer approach called pain neuroscience…
- Trial name
- PNE (NCT06400329)
- Testing
- Pain Neuroscience Education, Standard Pain Education
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lisa Carlesso
Pain
Patient-Reported Effectiveness and Safety of Etoricoxib in Osteoarthritis (OA)(0663-113)
The purpose of this study is to collect disease burden of OA and the effectiveness and patient satisfaction of treatment by Etoricoxib in the normal practice setting.
- Trial name
- NCT00757627
- Testing
- etoricoxib
- Volunteers
- 500 people
- Sponsor
- Organon and Co
Chronic Low Back Pain, Facet Joint Syndrome
MRgFUS and RFA for Treatment of Facet-joint Osteoarthritis Low Back Pain
This is a prospective, randomized, two-arm, phase II study. The purpose of this study is: To evaluate and compare the efficacy and safety of magnetic resonance-guided focused ultrasound (MRgFUS) and radiofrequency ablation (RFA)…
- Trial name
- NCT03168802
- Testing
- MRgFUS ablation, Radiofrequency ablation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Medical University Hospital
Osteoarthritis of the Knee
Study of FX006 in Patients With Osteoarthritis of the Knee
The purpose of this study was to evaluate the safety, efficacy and pharmacokinetics of FX006 in patients with osteoarthritis of the knee.
- Trial name
- NCT01487161
- Testing
- FX006, TCA IR
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 229 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Knee Osteoarthritis
Effects of Two Bar Knee Off-Load Brace With Non Weight Bearing Strength Training Among Knee Osteoarthritis Patients
The current study is a single-blind, parallel-group randomized controlled trial involving 18 participants with knee osteoarthritis.
- Trial name
- NCT07562646
- Testing
- Two-Bar Knee Off-Load Brace with Non-Weight Bearing Strength Training Intervention, Standard Knee Off-Loader Brace with Non-Weight Bearing Strength Training Intervention
- Volunteers
- 18 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Osteoarthritis
Effect of Glucosamine on Joint Structure and Quality of Life (JOG)
The goal of this study is 1) to develop a biomarker of of cartilage synthesis by determining if there is a relationship between changes in the status of knee cartilage and the amount of a biomarker called CTX-II in urine.
- Trial name
- NCT00377286
- Testing
- Glucosamine (a dietary supplement), 16 oz lite lemonade
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Pittsburgh
Knee Osteoarthritis, Knee Pain Chronic
Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis
The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Central Pain Syndrome
- Trial name
- NCT06105788
- Testing
- Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Knee Osteoarthritis, Total Knee Arthroplasty
Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty
This prospective, single-center, randomized controlled trial investigates the effects of preoperative cold therapy on early postoperative outcomes in patients undergoing unilateral primary total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Cryotherapy, Postoperative Pain Management
- Trial name
- NCT07134283
- Testing
- Preoperative and Postoperative Cold Therapy with Gel Cold Pack, Postoperative Cold Therapy with Gel Cold Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Ankara City Hospital Bilkent
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