Clinical trials: Osteoarthritis Pain
Osteoarthritis, Knee, Chronic Pain
Ultrasound-guided Genicular Nerve Block With Phenol for the Treatment of Chronic Pain Due to Knee Osteoarthritis
Osteoarthritis (OA) is one of the most frequent causes of chronic pain, often intense, debilitating and responsible for a large percentage of the elderly.
- Trial name
- NCT03601533
- Testing
- Phenol
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Federal University of São Paulo
Osteoarthritis, Knee
Efficacy and Safety of a Intra-articular Injection, ENKO1, in Patients With Symptomatic Knee Osteoarthritis.
Clinical trial with medical device, multicenter, single-blind (blind third party evaluation), randomized, comparative and in two paralell groups, to demonstrate the treatment according to usual clinical practice, of the…
- Trial name
- ENKORE (NCT03762408)
- Testing
- ENKO 1, Durolane
- Where
- 18 sites in Spain
- Volunteers
- 175 people
- Sponsor
- OPKO Health, Inc.
Osteoarthritis
To Compare Anterior Knee Pain Between Non Severe and Severe Patellofemoral Arthritis After Oxford UKA
The aims of this study is to compare the results between patients without severe patellofemoral arthritis and patients with severe patellofemoral arthritis after mobile bearing UKA.
- Trial name
- NCT02557763
- Testing
- Oxford unicompartmental knee arthroplasty
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Osteoarthritis of Knee, Healthy Participants
Evaluation of Muscle Oxygenation and Recovery Dynamics in Individuals With Knee Osteoarthritis
Knee osteoarthritis (OA) is a degenerative joint disease characterized by pain, muscle weakness, and functional limitations that significantly affect lower limb muscle performance.
- Trial name
- NCT07471204
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Osteoarthritis of Hip, Osteoarthritis, Knee
Chlorzoxazone in Hip and Knee Arthroplasty
The purpose of this study is to elucidate whether patients operated with THA and TKA can benefit from treatment with chlorzoxazone.
- Trial name
- chlorzoxazon (NCT02405104)
- Testing
- chlorzoxazone, THA, TKA
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis
The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.
The objective of this study is to demonstrate the effectiveness and tolerability of the buprenorphine transdermal system (5, 10, and 20 mg) in comparison to placebo transdermal system and immediate release oxycodone/acetaminophen…
- Trial name
- NCT00315848
- Testing
- Buprenorphine transdermal delivery system
- Where
- 10 sites in United States
- Volunteers
- 225 people
- Sponsor
- Purdue Pharma LP
Osteoarthritis
The Clinical Effect of Pregabalin on Neuropathic Pain in Central Sensitized Patients After Total Knee Arthroplasty
In this study, patients scheduled to undergo total knee arthroplasty (TKA) will be screened through a survey for patients with central sensitivity and patients with neuropathic pain as preoperative evaluation.
- Trial name
- NCT05254652
- Testing
- Duloxetine 30mg, Pregabalin 150mg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- The Catholic University of Korea
Knee Osteoarthritis
Self Transcranial Direct Current Stimulation and Mindfulness-based Meditation for Pain in Older Adults With Knee Osteoarthritis
The purpose of this study is to determine the feasibility and preliminary efficacy of a two-week self tDCS and mindfulness-based meditation for pain in older adults with knee osteoarthritis (OA).
- Trial name
- NCT03747640
- Testing
- Self Transcranial Direct Current Stimulation (tDCS), mindfulness-based meditation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Osteoarthritis, Knee
Preliminary Evaluation of Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Osteoarthritic Pain
Preliminary Evaluation of Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Osteoarthritic Pain - Dose escalation
- Trial name
- NCT03282149
- Testing
- XT-150
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Xalud Therapeutics, Inc.
Osteoarthritis (OA) of the Knee, Knee Pain Arthritis
Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if imageless navigation is not inferior to image-based navigation in robotic-assisted total knee arthroplasty (RA-TKA) for treating patients with knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Knee Pain Arthritis, Total Knee Arthroplasty (TKA), Robotic Assisted Arthroplasty
- Trial name
- NCT07522489
- Testing
- Imageless Robotic-Assisted Total Knee Arthroplasty, Image-based Robotic-Assisted Total Knee Arthroplasty
- Where
- Poland
- Volunteers
- 146 people
- Sponsor
- Medical University of Warsaw
Knee Osteoarthritis
Short Term Efficacy of High-intensity Laser Therapy in Patients With Knee Osteoarthritis
Knee osteoarthritis (KOA) is one of the most common health problems around the world. According to this, several interventions have been used to treat this group of patients including pharmacological and non-pharmacological…
- Trial name
- NCT04889885
- Testing
- High-intensity laser therapy (HILT)
- Volunteers
- 42 people
- Sponsor
- Mahidol University
Chronic Knee Pain, Osteoarthritis, Knee
Radiofrequency For Chronic Knee Pain Post-Arthroplasty
Chronic knee osteoarthritis (OA) is one of the most common diseases with increasing prevalence in advanced age. Knee OA results in movement restriction, sleep disturbance, and disability.
- Trial name
- DEFIANT (NCT02931435)
- Testing
- Nerve Block with Radiofrequency Ablation
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Randall Brewer, MD, CPI
Osteoarthritis, Knee
Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
To evaluate the efficacy, safety, tolerability, pharmacodynamics, and pharmacokinetics in patients with osteoarthritic pain of the knee.
- Trial name
- NCT00689273
- Testing
- PF-04136309
- Where
- 22 sites in United States, South Korea
- Volunteers
- 159 people
- Sponsor
- Pfizer
Osteo Arthritis Knee, Pain
Exercise-related Irisin on Inflammation and Pain
Osteoarthritis (OA) is a chronic disease that usually starts with cartilage damage in weight-bearing joints and then causes pain and loss of function secondary to damage in surrounding tissues.
- Conditions
- Osteo Arthritis Knee, Pain, Inflammation
- Trial name
- NCT05388994
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Firat University
Osteoarthritis, Knee, Osteoarthritis, Hip
Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
The primary objective of the study is to evaluate the efficacy of fasinumab compared to placebo, when administered for up to 24 weeks in patients with pain due to osteoarthritis (OA) of the knee or hip.
- Trial name
- FACT OA2 (NCT03304379)
- Testing
- Fasinumab, Diclofenac, Celecoxib
- Where
- 71 sites in United States
- Volunteers
- 1,650 people
- Sponsor
- Regeneron Pharmaceuticals
Hip Osteoarthritis, Hip Arthropathy
The Pericapsular Nerve Block in Total Hip Arthroplasty
In order to continue progressing towards outpatient total hip arthroplasty (THA), methods to adequately manage postoperative pain is of paramount importance.
- Trial name
- PENG (NCT04729686)
- Testing
- Pericapsular Nerve Block, Fascia Iliaca Nerve Block
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- LifeBridge Health
Osteoarthritis, Knee
Changes in Skin Autoflouresence Following Weight Loss and Maintenance Using Liraglutide in Knee Osteoarthritis
This is sub-study to a randomised, double blind, placebo-controlled, parallel group, and single-centre trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis…
- Trial name
- NCT02910570
- Testing
- Liraglutide 3 mg (Saxenda)
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Parker Research Institute
Osteoarthritis of the Knee, Type 2 Diabetes Mellitus
Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes
The purpose of this study was to compare the effects of FX006 and Triamcinolone Acetonide Injectable Suspension, United States Pharmacopeia (USP) (referred to as TCA IR in the protocol) on blood glucose (BG) in patients with…
- Trial name
- NCT02762370
- Testing
- FX006 32 mg, TCA IR 40 mg
- Where
- 8 sites in United States
- Volunteers
- 33 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis, Knee Arthritis Osteoarthritis
The Effect of Two Different Analgesic Methods on QoR-40 Score in Primary Unilateral Knee Arthroplasties
Total knee arthroplasty (TKA) is a very common operation that increases in frequency with advancing age. Similar to other surgical procedures, strategies are being developed to minimize morbidity and mortality while allowing for…
- Conditions
- Osteoarthritis, Knee Arthritis Osteoarthritis, Knee Arthroplasty, Total
- Trial name
- NCT07236073
- Testing
- PRİMER TEK TARAFLI DİZ ARTOPLASTİSİNDE İKİ FARKLI ANALJEZİK YÖNTEMİ, knee replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Knee Osteoarthritis
Pain Informed Movement for People With Knee Osteoarthritis
The goal of this clinical trial is to compare a pain informed movement program to standard neuromuscular exercise in people with knee osteoarthritis. The main question it aims to answer are: 1.
- Trial name
- NCT05730829
- Testing
- pain informed movement, standard neuromuscular exercise, Pain Neuroscience Education (PNE)
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- McMaster University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.