Clinical trials: Osteoarthritis Thumb
Osteoarthritis, Osteoarthritis Thumb Base Joint
Efficacy of a Single Injection of CTM for Post-Operative CMC Arthritis
The goal of this study is to determine the success rate of a single Carpometacarpal (CMC) thumb injection after arthroplasty surgery for primary osteoarthritis of the CMC joint.
- Conditions
- Osteoarthritis, Osteoarthritis Thumb Base Joint, Carpometacarpal Osteoarthritis, Thumb
- Trial name
- CTM CMC (NCT06171529)
- Testing
- CTM
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana Hand to Shoulder Center
Thumb Osteoarthritis
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis.
- Trial name
- NCT05992883
- Testing
- Ketorolac, Triamcinolone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Mayo Clinic
Osteoarthritis Thumb
Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis
A placebo-controlled randomized controlled trial exploring the effect of intraarticular steroids, saline or an occupational therapy intervention in inflammatory carpometacarpal-1 osteoarthritis
- Trial name
- PICASSO (NCT06084364)
- Testing
- Injection of triamcinolone acetonide into the CMC-1 joint, Multimodal Occupational therapy for CMC-1 joint OA
- Where
- 6 sites in Norway
- Volunteers
- 354 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis
Safety Study of Thumb Orthoses in Osteoarthritis in the Base of the Thumb (BTOA)
The prevalence of digital osteoarthritis varies according to whether a radiological or clinical definition is adopted. Interventions: Thumb orthoses to be worn at night and usual care vs usual care.
- Trial name
- NCT00350896
- Testing
- Thumb orthoses
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Arthritis Wrist
Orthotic Management of CMC Osteoarthritis
This study will investigate the effectiveness of 3D printed splints for the treatment of thumb osteoarthritis (CMC OA). Currently, these splints are made by Occupational Therapists and Physical Therapists out of low temperature…
- Trial name
- NCT04297943
- Testing
- Orthosis fabrication, Thermal Sensor Monitoring of Orthosis Use, 4D CT Scan
- Volunteers
- 68 people
- Sponsor
- Western University, Canada
Lactobacillus Plantarum
Lactobacillus Plantarum: Thumb Osteoarthritis Following Orange Peeling
Case Description osteoarthritis + amputation of the distal phalanx of the right thumb caused by Lactobacillus plantarum after an orange peel.
- Trial name
- NCT02884336
- Testing
- No intervention
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Thumb Osteoarthritis, Muscle Atrophy or Weakness
Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters…
- Trial name
- NCT04913935
- Testing
- Muscle-Skeleton Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Rizarthrosis
Comparative Study Between the Use of Trapeziometacarpal Prostheses and the Usual Resection-tenosuspension Arthroplasty for the Treatment of Rhizarthrosis, Focusing on Changes in Pain (Measured With the VAS Scale) and Function (With the Quick-DASH).
It is a randomized, prospective, single-blind study of two treatment techniques for rhizarthrosis. The patients are divided into two groups: one in which a Maia trapeziometacarpal prosthesis is implanted, and the other in which…
- Trial name
- NCT07101887
- Testing
- Implantation of thumb prosthesis, Burton-Pellegrini technique
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Parc de Salut Mar
Osteoarthritis Thumb Base Joint
Thumb Hemi-Arthroplasty With Natural Kinematics (THANKS) Trial
This clinical trial aims to evaluate the safety and effectiveness of the lnDx Implant in the treatment of thumb base joint arthritis.
- Trial name
- THANKS (NCT05644132)
- Testing
- InDx Implant for the carpometacarpal joint
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Loci Orthopaedics
Thumb Osteoarthritis
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the…
- Trial name
- NCT04828954
- Testing
- Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Carpometacarpal Osteoarthritis, Rhizarthrosis
Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis
This study compares and evaluates differences in movement analysis, patient-reported outcome, radiological assesment and muscular function between patients undergoing carpometacarpal joint arthroplasty with use of modern implants…
- Conditions
- Carpometacarpal Osteoarthritis, Rhizarthrosis, Thumb Osteoarthritis
- Trial name
- NCT04588961
- Testing
- Trapeziectomy with suspensionplasty, Joint alloplasty
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis
Function Following Thumb MP Fusion and IP Fusion
This study is to determine function following simulated thumb metacarpophalangeal (MP) and thumb interphalangeal (IP) joint fusion. The investigators want to determine the functional limitation created by MP and IP joint fusion.
- Trial name
- NCT03661281
- Testing
- Jebsen Taylor Hand function test, Pinch strength, Grooved pegboard test
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Thumb Osteoarthritis
Ligament Reconstruction Weilby vs Simple Trapeziectomy
There is currently no consensus on the best surgical approach for carpometacarpal osteoarthritis treatment. Simple trapeziectomy (TI) or trapeziectomy with ligament reconstruction tendon interposition (LRTI) are both accepted…
- Trial name
- WEILBY (NCT03858946)
- Testing
- Simple trapeziectomy, Weilby
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Thumb Osteoarthritis
Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis
Compare outcomes of ARA for isolated CMC OA versus to simultaneous ARA of CMC plus STT
- Trial name
- ARA:BJA-OA (NCT02958137)
- Testing
- Arthroscopic Resection Arthroplasty
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Specialist, PC, Davenport, IA
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Outcomes of Treatment for Trapeziometacarpal Osteoarthritis
The main objective of the study is the evaluation of the outcomes following treatment for TMC OA using a set of variables covering all OMERACT categories as well as the dimensions of the International Classification of…
- Trial name
- RASSH (NCT01724853)
- Testing
- Surgery, Conservative
- Where
- Switzerland
- Volunteers
- 177 people
- Sponsor
- Schulthess Klinik
Thumb Osteoarthritis, First Dorsal Interosseous Strengthening
Strengthening of the First Dorsal Interosseous for Thumb Carpometacarpal Osteoarthritis
To determine the effect of first dorsal interosseus (FDI) strengthening in patients with thumb carpometacarpal (CMC) osteoarthritis.
- Trial name
- NCT03177577
- Testing
- Splint, Splint with strengthening exercises
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Thumb Osteoarthritis
Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis
Long-Term Objective: Determine if high-frequency PEMF therapy reduces pain in patients with thumb carpometacarpal (CMC) joint osteoarthritis (OA).
- Trial name
- NCT05315297
- Testing
- PEMF device
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Stanford University
Thumb Arthritis
The Impact of Thumb Carpometacarpal Osteoarthritis on General Health
This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of…
- Trial name
- NCT01133197
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Washington University School of Medicine
Osteoarthritis Thumb
The Effects of Two Different Orthosis on Pain, Hand Strength and Function in Patients With Thumb Carpometacarpal Osteoarthritis
The investigators aimed to assess the effects of two different hand orthosis on hand functioning, pain, disability and quality of life in patients with thumb osteoarthritis
- Trial name
- NCT03327480
- Testing
- orthosis
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital