Clinical trials: Osteoarthritis Thumb
Thumb Osteoarthritis
Turmeric for Patients With Basal Joint Arthritis
The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis.
- Trial name
- NCT03017118
- Testing
- Turmeric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Thumb Carpometacarpal Joint Osteoarthritis
Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
Arthritis of the base of the thumb is a common debilitating problem. It is believed that laxity (loosening) of the joint leads to worsening arthritis in this joint.
- Trial name
- NCT00685880
- Testing
- Prolotherapy (10% dextrose solution), Betamethasone
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoarthritis, Osteoarthritis Thumbs
Prospective Clinical Study to Evaluate the Safety and Efficacy of Intraarticular Administration of Micro-grafts of Adipose Tissue (Adipo-micro-grafts) in the Treatment of Osteoarthritis of the Trapezium-metacarpal Joint (ADIPO_MICRO_GRAFTS_1)
The objective of this interventional study is the Change in the Michigan Hand Questionnaire (MHQ) score over time in subjects with Eaton Littler grade II and III trapeziometacarpal osteoarthritis.
- Trial name
- AMG_1 (NCT06997991)
- Testing
- adipose micro-grafts injection
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Rizarthrosis
Comparative Study Between the Use of Trapeziometacarpal Prostheses and the Usual Resection-tenosuspension Arthroplasty for the Treatment of Rhizarthrosis, Focusing on Changes in Pain (Measured With the VAS Scale) and Function (With the Quick-DASH).
It is a randomized, prospective, single-blind study of two treatment techniques for rhizarthrosis. The patients are divided into two groups: one in which a Maia trapeziometacarpal prosthesis is implanted, and the other in which…
- Trial name
- NCT07101887
- Testing
- Implantation of thumb prosthesis, Burton-Pellegrini technique
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Parc de Salut Mar
Thumb Osteoarthritis
Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty
This study aims to compare post-surgical outcomes of individuals who receive either a custom orthosis or prefabricated splint after carpometacarpal arthroplasty.
- Trial name
- NCT05307510
- Testing
- Prefabricated splint, Custom Orthosis
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Toledo
Carpometacarpal (CMC) Joint Arthritis
Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting
The oval-8 splint has been developed for many uses in finger pathology and trauma. It has not, however, been used to treat thumb carpometacarpal (CMC) joint arthritis.
- Trial name
- Oval-8 (NCT02266095)
- Testing
- Oval-8 Splint, Tee Pee Splint, Forearm Based Splint
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Hand Osteoarthritis, Wrist Osteoarthritis
Effects of 12-week Digital Treatment in Patients With Hand OA on Pain and Function
The purpose of this study is to evaluate the effect of a 12 week digital treatment program for patients with hand osteoarthritis.
- Conditions
- Hand Osteoarthritis, Wrist Osteoarthritis, Thumb Osteoarthritis, Finger Osteoarthritis
- Trial name
- NCT05499559
- Testing
- Joint Academy digital treatment
- Where
- Sweden
- Volunteers
- 846 people
- Sponsor
- Joint Academy
Osteoarthritis Thumb
Post Market Clinical Follow-Up TOUCH® CMC 1
Because severe pain, weakened pinch and grip strength produce functional disabilities, the basal joint of the thumb is the most common site of surgical reconstruction in the upper limb due to OA.
- Trial name
- NCT06546306
- Testing
- TOUCH® CMC 1
- Where
- 6 sites in France
- Volunteers
- 216 people
- Sponsor
- Keri Medical SA
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Rhizarthrosis
Dual Mobility Total Joint Prosthesis (Touch) for Thumb Carpometacarpal Joint Osteoarthritis
The dual mobility concept currently represents the newest generation of thumb carpometacarpal prostheses. The aim of this study was to evaluate the outcomes of TOUCH® prosthesis.
- Trial name
- NCT05047744
- Testing
- Touch Dual Mobility CMC I Prosthesis
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Kepler University Hospital
Osteoarthritis Thumb Base Joint
Thumb Hemi-Arthroplasty With Natural Kinematics (THANKS) Trial
This clinical trial aims to evaluate the safety and effectiveness of the lnDx Implant in the treatment of thumb base joint arthritis.
- Trial name
- THANKS (NCT05644132)
- Testing
- InDx Implant for the carpometacarpal joint
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Loci Orthopaedics
Hand Osteoarthritis
Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis
The aim of this study is to compare the effect of Whale and Colditz static orthosis on pain and functional abilities of hand in thumb carpometacarpal osteoarthritis as a unique treatment.
- Trial name
- NCT02780999
- Testing
- Whale orthosis, Colditz orthosis
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Osteoarthritis Thumbs
A Study To Assess The Ability Of Tramadol, Naproxen And Oxycodone To Affect The Pain Thresholds Of Patients With Osteoarthritis Of The Thumb
The purpose of this study is to determine if the measurement of pressure pain thresholds, in patients suffering osteoarthritis of the thumb, can be used to assess the activity of potential analgesic agents after a single dose.
- Trial name
- NCT00743587
- Testing
- Oxycodone, Tramadol, Naproxen
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Pfizer
Osteoarthritis
Use of Autologous Adipose-Derived Stromal Vascular Fraction To Treat Osteoarthritis of Hip, Knee, Ankle, and Thumb Joints
This study will examine the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF) cells for treatment of hip, knee and thumb osteoarthritis (OA); monitoring adverse events and measuring pain, function…
- Trial name
- NCT03166410
- Testing
- Cell injection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Texas Plastic Surgery
Osteoarthritis Thumb, Joint Diseases
Touch on One Thumb, RSI on the Other Thumb: Which Surgery Shows Better Results
The study aims to determine whether CMC I arthroplasty using a Touch® implant results in higher patient satisfaction compared to RSI arthroplasty in the medium-term in patients with primary thumb osteoarthritis.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Musculoskeletal Diseases or Conditions, Osteoarthritis
- Trial name
- NCT05849506
- Testing
- Touch® Prosthesis
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Schulthess Klinik
Thumb Osteoarthritis, Thumb Injury
Validity And Reliability of the Turkish Version of the Thumb Disability Examination
Purpose of the study is the validity and reliability of the Turkish version of The Thumb Disability Examination (TDX) so that it would be used as an assessment tool for Turkish thumb patients.
- Conditions
- Thumb Osteoarthritis, Thumb Injury, Thumb Fracture, Thumb Laceration
- Trial name
- NCT04627259
- Testing
- Thumb Disability Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Hacettepe University
Carpometacarpal Osteoarthritis, Rhizarthrosis
Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis
This study compares and evaluates differences in movement analysis, patient-reported outcome, radiological assesment and muscular function between patients undergoing carpometacarpal joint arthroplasty with use of modern implants…
- Conditions
- Carpometacarpal Osteoarthritis, Rhizarthrosis, Thumb Osteoarthritis
- Trial name
- NCT04588961
- Testing
- Trapeziectomy with suspensionplasty, Joint alloplasty
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw
Thumb Osteoarthritis
Efficacy of Trapeziectomy Versus Sham Surgery in the Treatment of Osteoarthritis at the Base of the Thumb
A multi-center randomized placebo-controlled clinical trial which determines the efficacy of trapeziectomy in patients with persistent painful osteoarthritis at the base of the thumb.
- Trial name
- FINTASY (NCT05127005)
- Testing
- Trapeziectomy
- Where
- 4 sites in Finland
- Volunteers
- 132 people
- Sponsor
- Tampere University Hospital
Thumb Osteoarthritis
Effectiveness of Intra-articular Oxygen-ozone Injections and Splinting for the Treatment of Thumb Osteoarthritis
Osteoarthritis of trapezio-metacarpal joint (TMJ) most commonly occurs in women over 50 years old, often bilateral and it is a disabling condition presenting with pain at base of the thumb, swelling, instability, deformity and…
- Trial name
- NCT07171840
- Testing
- 10 cc of oxygen-ozone plus thumb splint, thumb splint
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Humanitas Clinical and Research Center
Osteoarthritis Thumb
Comparison of the Efficacy of Intra-articular Hybrid Hyaluronic Acid and Steroid in Patients With Rizoarthrosis
Osteoarthritis of the trapeziometacarpal joint (TMJ), also called rhizarthrosis is a common disease, mostly affecting post-menopausal women.
- Trial name
- NCT03200886
- Testing
- Sinovial H-L, Triamcinolone Acetonide
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Siena