Clinical trials: Osteoarthritis of Hands
Hand Osteoarthritis, Erosive Osteoarthritis
Methotrexate in Erosive Inflammatory Hand Osteoarthritis
A placebo-controlled randomized controlled trial exploring the effect of methotrexate on pain, function and structural outcomes in erosive inflammatory hand osteoarthritis.
- Trial name
- MERINO (NCT04579848)
- Testing
- Methotrexate Tablets, Folic Acid 1 MG
- Where
- Norway
- Volunteers
- 163 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis Hand, Lumbago
Cardiovascular Risk in Digital Osteoarthritis
The goal of this cross-sectional case control study is to investigate the cardiovascular risk in digital osteoarthritis. This study aims to compare the cardiovascular risk between group of patients with digital osteoarthritis and…
- Conditions
- Osteoarthritis Hand, Lumbago, Osteoporosis, Radiculopathy Lumbar
- Trial name
- RICARDI (NCT05923736)
- Testing
- Intima media thickness ultrasound, hand ultrasound, EndoPAT™ 2000 system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoarthritis
Synergic Effects of Ultrasound and Laser on the Pain Relief and Functionality
There are several therapeutic effects of the ultrasound (US) or low level laser therapy (LLLT), including pain relief, increase of microcirculation, modulation of inflammatory response and accelerated tissue repair.
- Trial name
- NCT02154893
- Testing
- Ultrasound plus Laser and therapeutic exercise, Ultrasound plus Laser
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo
Thumb Osteoarthritis, CMC
3D-Printed Hand Orthosis Versus Thermoplastic Orthosis
This study will investigate the effectiveness of 3D-printed splints for treating thumb osteoarthritis (CMC OA). These splints are made by Occupational Therapists and Physical Therapists out of low-temperature plastic and formed…
- Conditions
- Thumb Osteoarthritis, CMC, Splints
- Trial name
- NCT05896410
- Testing
- splint (orthosis)
- Volunteers
- 10 people
- Sponsor
- Western University, Canada
Osteoarthritis of the Hand
AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint
This study will evaluate the safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the basal thumb joint.
- Trial name
- NCT02762760
- Testing
- AMPION™, Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand
Effectiveness of an Exercise Program and Education Through a Mobile Application for the Management of Patients With Hand Osteoarthritis and Rheumatoid Arthritis
Strengthening and stretching exercise programs, and recommendations to protect the affected joint have shown to be effective both clinically and economically in conditions such as hand osteoarthritis and hand rheumatoid…
- Conditions
- Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand, Pain, Mobility Limitation
- Trial name
- NCT04263974
- Testing
- Smartphone Application, Conventional treatment
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- University of Seville
Osteoarthritis, Osteoarthritis Finger
Effects of Using Custom Photobiomodulation Therapy for the Treatment of Osteoarthritis of the Fingers and Rhizarthrosis
Osteoarthrosis (OA), a multifactorial degenerative process, is responsible for joint pain and functional limitation. In the hand, more specifically in the proximal and distal interphalangeal joints of the fingers, it is one of…
- Conditions
- Osteoarthritis, Osteoarthritis Finger, Osteoarthritis Hand, Osteoarthritis Both Hands
- Trial name
- NCT05041231
- Testing
- Photobiomodulation therapy (PBT)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Vita Care
Osteoarthritis
Study of the Use of Laser Light to Treat Osteoarthritis of the Hand.
The purpose of this study is to determine whether low level light therapy is effective in the treatment of osteoarthritis of the hand, when the treatment is applied to the hand by an individual in his or her own home.
- Trial name
- NCT00254111
- Testing
- Ultra Probe Laser System
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- TriTech Manufacturing
Erosive Osteoarthritis of the Hand
Prescription-grade Crystalline Glucosamine Sulfate Therapy in Erosive Hand Osteoarthritis
The objective of this study is to evaluate the efficacy of prescription-grade Crystalline Glucosamine Sulfate (pCGS), as an add-on treatment to conventional therapy, compared to usual therapy alone, in patients with erosive…
- Trial name
- NCT05237596
- Testing
- Glucosamine Sulfate
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- University of Siena
Osteoarthritis
Efficacy and Safety of Diclofenac Sodium Gel in Hand Osteoarthritis
This study will test the efficacy and safety of topical diclofenac sodium gel in the treatment of hand osteoarthritis.
- Trial name
- NCT00171652
- Testing
- Diclofenac sodium gel 1%
- Where
- 48 sites in France, Germany
- Volunteers
- 360 people
- Sponsor
- Novartis
Osteoarthritis, Cardiovascular Risk Factors
Osteoarthritis Cardiovascular Risk Factors
We analyze retrospectively the relationship between traditional cardiovascular risk factors as hypertension, obesity, dislipidemia and diabetes and hand or knee osteoarthritis and we compare the results with a control groups of…
- Conditions
- Osteoarthritis, Cardiovascular Risk Factors, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT01902654
- Testing
- Cardiovascular risk factors diagnoses collection., History of cardiovascular disease, Cardiovascular risk factors association
- Where
- Spain
- Volunteers
- 490 people
- Sponsor
- Parc Taulí Hospital Universitari
Osteoarthritis Hand
S-Asenosyl-L-Methionine vs Placebo for Osteoarthritis of the Hands
The primary objective of this study is to demonstrate the feasibility of evaluating SAMe tolerability, analgesic benefits, and daily functional improvement in patients with osteoarthritis of the hands compared to placebo.
- Trial name
- SAMe (NCT05363020)
- Testing
- S-Adenosyl-L-Methionine (Sam-E)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hand Osteoarthritis
Comparison of Effect of Prolotherapy and Paraffin Waxes for Hand Osteoarthritis
Patients with hand osteoarthritis will be randomized into two groups, paraffin wax and prolotherapy group. Patients will be evaluated before and after treatment , after 2 weeks 4 weeks and 3 months after treatment.
- Trial name
- NCT03839108
- Testing
- Paraffin wax, Prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Thumb Osteoarthritis, Muscle Atrophy or Weakness
Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters…
- Trial name
- NCT04913935
- Testing
- Muscle-Skeleton Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Osteoarthritis
Effect of Diacerein on Hand Osteoarthritis
Ostearthritis is one of the most common arthritis, affecting more than 30% of aged people world-widely. The disease is characterized by pain and stiffness of the affected joints and is the most common cause of disability in aged…
- Trial name
- NCT00685542
- Testing
- diacerein
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Hand, Hand Therapy
Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System
This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later.
- Conditions
- Hand, Hand Therapy, Upper Extremity, Prediction Models
- Trial name
- HANDREHPREDICT (NCT07522060)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Soft Tissue Injuries, Distal Radius Fracture
Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers.
Trauma and soft injuries of the wrist, hand and fingers have a high incidence, and large social and healthcare costs are generated, mainly due to productivity loss.
- Conditions
- Soft Tissue Injuries, Distal Radius Fracture, Metacarpal Fracture, Carpal Fracture
- Trial name
- NCT04669704
- Testing
- Experimental: Tablet application, Comparator: Conventional treatment
- Where
- 2 sites in Spain
- Volunteers
- 663 people
- Sponsor
- University of Seville
Hand Osteoarthritis, Erosive Osteoarthritis
A 30-month Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate in Erosive Hand OA.
In response to the high prevalence of synovitis in hand osteoarthritis (OA) and its association with pain, there\'s a compelling rationale for investigating the efficacy of MTX in managing inflammatory erosive hand OA.
- Trial name
- MERINO:2 (NCT06281184)
- Testing
- Methotrexate, Treatment as usual
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- Diakonhjemmet Hospital
Flexor Tendon Rupture, Thumb Osteoarthritis
Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting
This will be a prospective randomized control trial with a blocking method to determine the effect of an occupational therapy focused pre-operative education on 3 pre-determined diagnosis: Carpometacarpal (CMC) Arthroplasty…
- Conditions
- Flexor Tendon Rupture, Thumb Osteoarthritis, Distal Radius Fracture
- Trial name
- NCT05095415
- Testing
- Occupational Therapy Pre-operative Consult, Typical Pre-Operative Education
- Sponsor
- Methodist University, North Carolina