Clinical trials: Osteoarthritis of Hip
Osteoarthritis, Knee, Osteoarthritis, Hip
Robotic Assisted Rehabilitation for Balance and Gait in Orthopedic Patients.
Osteoarthritis is a chronic, degenerative disease affecting the joints. It is characterized by the presence of bone tissue that goes to make up for the loss of articular cartilage, causing pain and limitation of movement.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Gait Disorders in Old Age, Balance; Distorted
- Trial name
- NCT05459584
- Testing
- Technological Rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Osteoarthritis, Vitamin D Deficiency
Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA)
The purpose of this study is being conducted to determine whether correcting low levels of vitamin D with a single high-dose supplement reduces complications after the participant's primary TJA.
- Trial name
- NCT07006714
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
Acetabular Labrum Tear, Femoro Acetabular Impingement
Arthroscopic Labral Repair Versus Physical Therapy for Tears of the Acetabular Labrum
Tears of the acetabular labrum appear to be common with the prevalence of asymptomatic tears in the general population approaching 66% and 70% based on cadaveric dissection and magnetic resonance imaging, respectively.
- Conditions
- Acetabular Labrum Tear, Femoro Acetabular Impingement, Hip Arthroscopy, Physical Therapy
- Trial name
- NCT03909178
- Testing
- Hip Arthroscopy Surgery with Acetabular Labral Repair (SPT group), Physical Therapy Focused on the Hip and Hemi-pelvis (PT group)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Massachusetts General Hospital
Hip Osteoarthritis, Hip Arthritis
Postural Control in Degenerative and Inflammatory Diseases of the Hip
Patients with primary hip osteoarthritis (OA group) and patients with inflammatory hip disease (RA group) and healthy subjects (control group) are enrolled in the study.
- Trial name
- PCHOAI (NCT03783806)
- Testing
- Posturography measurements
- Where
- Hungary
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Szeged University
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee
The study schedule consists of a Screening Period (up to 14 days), a blinded 4- week Titration-to-Effect Period with weekly visits, a blinded 4-week Maintenance Treatment Period at the optimal dose level determined for each…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Knee, Arthritis, Joint Diseases
- Trial name
- NCT02944448
- Testing
- CR845 tablet 1 mg, CR845 tablet 2.5 mg, CR845 tablet 5 mg
- Where
- 35 sites in United States
- Volunteers
- 761 people
- Sponsor
- Cara Therapeutics, Inc.
Osteoarthritis of Knee, Osteoarthritis Hip
Cannabinoids for Osteoarthritis Pain Effectiveness Trial
This study aims to investigate whether oral cannabis extracts can effectively manage pain caused by osteoarthritis (OA), a common joint condition affecting one in seven Canadians.
- Trial name
- COPE (NCT06878417)
- Testing
- CBD, THC
- Where
- 3 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Osteoarthritis
Local Anesthetic Infiltration and Infusion for Pain Control After Hip Replacement
The purpose of this study is to examine three different ways to control pain after hip replacement: 1. One time injection of ropivacaine before wound closure 2.
- Trial name
- NCT01409278
- Testing
- Ropivacaine infiltration and saline infusion., Ropivacaine infiltration and infusion., Normal Saline
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Trinity Health Of New England
Anesthesia, Conduction, Osteoarthritis, Hip
Pain and Sensation After Regional Anesthesia - Pilot Study
This study aims to determine spinal resolution and pain levels after the placement of a lumbar plexus block (LPB) and spinal for total hip replacement procedure.
- Trial name
- NCT03623035
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Knee Osteoarthritis, Hip Osteoarthritis
Quality of Care for Knee and Hip Osteoarthritis in Elderly Patients
Introduction: Hip and knee osteoarthritis (OA) was ranked in 2010 as the eleventh highest contributor to global disability. In France in 2014, non-spinal OA was the leading self-reported cause of morbidity among adults over…
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Quality of Healthcare, Elderly
- Trial name
- QSAMISA (NCT04170218)
- Where
- France
- Volunteers
- 405 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis, Knee
The Influence of Hip Strengthening Exercises on Walking Patterns and Muscle Strength in Persons With Knee Osteoarthritis
The purpose of this study is to determine the influence of a home program of exercises for the hip muscles which support the pelvis on walking patterns and hip muscle strength in people with knee osteoarthritis.
- Trial name
- NCT00427843
- Testing
- home exercise program for the hip abductor muscles
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Queen's University
Total Hip Arthroplasty, Osteoarthritis, Hip
Corin MiniHip and Trinity Cup Clinical Surveillance Study
The aim of the study is to provide long term follow up data on the performance and safety of the Corin MiniHip and Trinity acetabular cup over a 10-year period.
- Conditions
- Total Hip Arthroplasty, Osteoarthritis, Hip, Traumatic Arthritis of Hip, Rheumatoid Arthritis of Hip
- Trial name
- NCT05186168
- Testing
- MiniHip Stem, Trinity Acetabular Cup System
- Volunteers
- 546 people
- Sponsor
- Corin
Hip Osteoarthritis, Knee Osteoarthritis
Leisure Expectations About Physical Activity Study
To pilot test an activity-focused intervention that educates patients undergoing total hip (THA) or total knee (TKA) arthroplasty due to osteoarthritis about the appropriate type, frequency, intensity, and duration of expected…
- Trial name
- LEAP (NCT01938274)
- Testing
- Educational intervention
- Where
- United States
- Sponsor
- West Virginia University
Osteoarthritis of Hip
Hip Replacement System (HRS-P) in Primary Total Hip Arthroplasty
To evaluate effectiveness and safety of HHRS in subjects undergoing total hip arthroplasty (THA). Effectiveness will be evaluated using patient-reported, clinical, radiologic, and radiostereometric outcomes.
- Trial name
- (HRS-P) (NCT02836262)
- Testing
- HIT Hip Replacement System
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hip Innovation Technology
Total Hip Replacement, Coxarthrosis
Comparison of the Use of Conventional Ancillary Reaming and Single-use Ancillary Reaming Material in Total Hip Replacement
The main objective of the study is to compare the use of single-use ancillary reaming material during total hip replacement and conventional reusable ancillary reaming material.
- Trial name
- LUUC (NCT04903860)
- Testing
- total hip replacement with single use ancillary, total hip replacement with conventional ancillary
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoarthritis, Hip, Arthritis
Longterm-Evaluation of Vitelene® Against Standard
The purpose of this randomised prospective multicenter longterm study is to evaluate the survival rate of the implant, wear and periprosthetic osteolysis of highly cross-linked polyethylene with and without addition of Vitamin E…
- Trial name
- VITAS (NCT01713062)
- Testing
- Vitelene, XLPE
- Where
- 6 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Aesculap AG
Cartilage Damage, Osteoarthritis, Hip
Histological Validation of dGEMRIC Indices as a Quantitative Biomarker for Cartilage Damage in the Hip Joint
In this study, the investigators seek to validate 3D model-based dGEMRIC (delayed gadolinium enhanced MRI of cartilage) values against histologic grading of cartilage quality, using osteochondral samples of the femoral head…
- Trial name
- NCT06185036
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coxarthrosis; Primary
Ceramic Modular Dual Mobility in Primary Total Hip Arthroplasty (THA)
A randomized controlled trial comparing modular dual mobility inserts with ceramic multilayer coating versus standard polyethylene inserts for primary THA in a cementless acetabular cup
- Trial name
- CeMoD-prime (NCT05547984)
- Testing
- Dual Mobility Cup, Standard Acetabular component
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Hip Osteoarthritis
Progressive Resistance Training Compared to Neuromuscular Exercise in Patients With Hip Osteoarthritis
The primary aim of this randomized controlled trial is to investigate the effectiveness of 12 weeks of progressive resistance training (PRT) compared to neuromuscular exercise (NEMEX) on functional performance in patients with…
- Trial name
- HipBooster (NCT04714047)
- Testing
- Progressive Resistance Training and no booster sessions, Progressive Resistance Training and booster sessions, Neuromuscular exercise and no booster sessions
- Where
- 3 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- University of Aarhus
Hip and Knee Osteoarthritis
Recovery After Fast Track THA / TKA
The development and implementation of "fast-track" principles in total knee and hip arthroplasty have resulted in early recovery and rehabilitation alongside a reduced length of hospital stay.
- Trial name
- 0-21 (NCT02137655)
- Where
- 2 sites in Denmark
- Volunteers
- 112 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Hip
Autologous Culture Expanded Adipose Derived MSCs for Treatment of Painful Hip OA
Will injection(s) of autologous culture-expanded AMSCs be safe and efficacious for treatment of painful Hip OA, and if so, which dosing regimen is most effective?
- Trial name
- NCT03608579
- Testing
- Autologous Adipose Derived Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic