Clinical trials: Osteoarthritis of Knee
Knee Osteoarthritis
Correlating the OA Knee Microenvironment to Outcomes After Regenexx-SD Treatment: A Multi-Site Study
Multi-center study to include up to 600 subjects with knee osteoarthritis in unilateral or bilateral knees treated with Regenexx® SD in the osteoarthritic knee/s.
- Trial name
- NCT03898388
- Testing
- Bone Marrow Concentrate treatment
- Where
- 3 sites in United States
- Volunteers
- 47 people
- Sponsor
- Regenexx, LLC
Osteoarthritis, Knee Osteoarthritis
Pain Management In Knee Osteoarthritis
In this study, it was aimed to investigate the effect of pain management education in individuals with knee osteoarthritis with chronic pain.
- Conditions
- Osteoarthritis, Knee Osteoarthritis, Pain, Chronic
- Trial name
- NCT05844319
- Testing
- tele-education
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Istanbul University
Osteoarthritis Knee
Comparison of an Old Versus a New Total Knee Replacement
A randomized controlled clinical and RSA study, comparing 2 knee implants: 1. NexGen CR cemented total knee arthroplasty 2. Persona CR cemented total knee arthroplasty 3 hospitals will participate in the study: Helse Bergen HF…
- Trial name
- NCT03548792
- Testing
- RSA radiostereometric analysis, Clinical comparison
- Where
- Norway
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Helse-Bergen HF
Knee Osteoarthritis
Race and Preference for Knee Replacement: A Patient-Centered Intervention
A randomized, controlled design will be utilized to examine and compare the effectiveness of the proposed educational intervention, which includes a combination of an educational decision aid and motivational interviewing with…
- Trial name
- REPAIR (NCT02413411)
- Testing
- DA/MI Intervention, an educational program (an NIH-developed booklet)
- Where
- United States
- Volunteers
- 493 people
- Sponsor
- University of Pennsylvania
Hip Fracture, Arthrosis
Preventing Loss of Weight, Fat Free Mass and Activities of Daily Living
Malnutrition of elder orthopaedic patients leads to weight loss and loss of fat free mass. Changes in the individual's nutritional status and body composition may adversely affect the patient's postoperative level of activity.
- Trial name
- NCT00373971
- Testing
- Involving the patients in their own nutritional care
- Where
- Denmark
- Volunteers
- 252 people
- Sponsor
- University of Aarhus
Osteoarthritis
Validation Study to Investigate the Effect of a New Treatment in Patients With Osteoarthritic Pain
The purpose of this clinical trial conducted in patients suffering from chronic pain is to study the relationship between individual patients' profile and their analgesic response
- Trial name
- NCT03174145
- Testing
- Positive behaviour, T4P1010 administration, Pharmacogenetic
- Where
- 6 sites in Belgium, France and 1 more
- Volunteers
- 73 people
- Sponsor
- Tools4Patient
Knee Osteoarthritis
Effect of Tai Chi Exercise on Mechanical Joint Loading in Knee Osteoarthritis
This project is designed to identify the biomechanical mechanisms of Tai Chi (TC) exercise and test a novel optimized TC intervention by modifying newly identified mechanisms for those with knee osteoarthritis (OA) and to assess…
- Trial name
- NCT03621631
- Testing
- Optimized Tai Chi intervention, Traditional Tai Chi intervention
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Osteo Arthritis Knee
Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis
The purpose of this study is to assess the feasibility, acceptability, and efficacy of self-administered transcranial direct current stimulation (tDCS) in older adults with knee osteoarthritis (OA)
- Trial name
- NCT04016272
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Florida State University
Osteo Arthritis of the Knee
Hydrogel Assessment for Local Treatment of Osteoarthritis
The study aims to evaluate the safety and tolerability of one intra-articular injection of Hydrogel OA 2% for the symptomatic treatment of osteoarthritis of the knee.
- Trial name
- HALO (NCT07516457)
- Testing
- Injection of Hydrogel OA 2%
- Where
- 3 sites in Belgium
- Volunteers
- 20 people
- Sponsor
- Allegro NV/SA
Knee Osteoarthristis
Daily Activity and Clinical Outcome Measurement of Arthrosamid® Administration in Symptomatic Knee Osteoarthritis.
This study is a prospective, monocentric, interventional post-market study evaluating the effects of a single intra-articular injection of Arthrosamid in patients with symptomatic knee osteoarthritis.
- Trial name
- ACTA (NCT07465601)
- Testing
- Arthrosamid
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Medisch Centrum Latem
Osteoarthritis, Knee
Treatment of Osteoarthritic Knee With High Tibial Osteotomy and Implantation of Allogenic Human Umbilical Cord Blood-derived Stem Cells.
The purpose of this study is to evaluate the clinical results after implantation of human umbilical cord blood-derived mesenchymal stem cells(hUCB-MSCs) and High tibia osteotomy in patients with medial compartment…
- Trial name
- NCT04234412
- Testing
- umbilical cord blood stem cell implantation for osteoarthritis treatment
- Volunteers
- 10 people
- Sponsor
- Uijeongbu St. Mary Hospital
Knee Osteoarthritis
Effect of Graston Technique Versus MET on Improving Hamstring Flexibility and ADLS in Knee Osteoarthritis
The objective of this study is to determine the comparison of Graston technique versus muscle energy technique to improve hamstring flexibility and ADL among patient of knee O.A.
- Trial name
- NCT05376995
- Testing
- Graston technique, muscle energy technique
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Superior University
Knee Disease, Knee Osteoarthritis
Ultrasound Guıded Adductor Canal Block vs Perıcapsular Nerve Group Block in Knee Artroplasty
Knee arthroplasty surgery numbers are increasing depending on joint deformities and cartilage degenerations. Severe postoperative pain may occur in these patients due to surgery and the placed prosthesis.
- Conditions
- Knee Disease, Knee Osteoarthritis, Knee Arthropathy
- Trial name
- NCT06203483
- Testing
- Adductor canal block, PENG block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Knee Osteoarthritis
Safety of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells in Subjects With Osteoarthritis
The aim of this study is to assess the safety of Stemedica's mesenchymal stem cells in patients with knee osteoarthritis. The route of administration is intraarticular.
- Trial name
- NCT03602872
- Testing
- Human allogeneic mesenchymal bone marrow derived stem cells
- Where
- Mexico
- Sponsor
- Clinica Santa Clarita, Mexico
Osteoarthritis, Knee, Diabete Type 2
Increased Blood Glucose Levels After Steroid Injection
a sample of 600 patients diagnosed as Knee osteoarthritis injected with 40 mg triamcinolone, recorded their morning fasting blood glucose levels for 7 days before injection used as the baseline blood glucose level, which was…
- Trial name
- NCT06228911
- Testing
- steroid (triamcinolone)
- Where
- Syria
- Volunteers
- 600 people
- Sponsor
- Syrian Private University
Knee Osteoarthritis
The Influence of Coronally Knee Alignment on the Tibial Tuberosity Rotation
The primary aim of this study is to find a possible correlation between tibial tuberosity rotation and coronal leg alignment. If correlation exists, a more individual tibial component rotation might be proposed during a total…
- Trial name
- NCT05295602
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- Valdoltra Orthopedic Hospital
Knee Osteoarthritis
Comparison Between Mobithron® and Crystalline Glucosamine Sulphate in Patients With Knee Osteoarthritis
Knee osteoarthritis is a common degenerative joint disorder that causes pain, functional limitation, and reduced quality of life.
- Trial name
- NCT07717957
- Testing
- Mobithron®, Crystalline Glucosamine Sulphate
- Where
- Malaysia
- Volunteers
- 34 people
- Sponsor
- BREGO Life Sciences
Osteo Arthritis Knee
Trial of Unicompartmental Versus Total Knee Arthroplasty
This study is a prospective, randomized trial to compare patient outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial compartment osteoarthritis.
- Trial name
- NCT03385759
- Testing
- Unicompartmental knee arthroplasty, Total knee arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Anderson Orthopaedic Research Institute
Knee Osteoarthritis
Pilot Study of Therapy With Hylan G-F 20 Exercise Capacity
Osteoarthritis of the knee is a degenerative joint disease that involves degradation of the joint. Symptoms include joint tenderness, pain, stiffness, locking, and occasionally an effusion.
- Trial name
- CORT (NCT01810848)
- Testing
- Hylan G-F 20, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- OhioHealth
Primary Gonarthrosis, Genu Recurvatum
The Results of Oxford Unicompartmental Knee Arthroplasty in Patients With and Without Preoperative Genu Recurvatum
The purpose of this study is to explore the effects of the Oxford unicompartmental knee arthroplasty on two groups of patients, namely one with genu recurvatum before the procedure and one without.
- Trial name
- NCT02854189
- Testing
- Oxford unicompartmental knee arthroplasty
- Volunteers
- 104 people
- Sponsor
- Thammasat University
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