Clinical trials: Osteoarthritis of the CMC-1 Joint
Thumb Osteoarthritis
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the…
- Trial name
- NCT04828954
- Testing
- Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Early Stage Osteoarthritis of the CMC-1 Joint
Clinical Evaluation of the Articulinx InterCarpoMetacarpal Cushion (ICMC)for Osteoarthritis of the First CarpoMetacarpal Joint
This study is to evaluate the performance of the Articulinx ICMC (InterCarpoMetacarpalCushion)in the carpometacarpal joint (CMC joint) and to describe the clinical results in patients who have been treated with this device.
- Trial name
- NCT01961570
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Articulinx
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Thumb Osteoarthritis
Postoperative Therapy After Interposition Arthroplasty in CMC1
In this randomized controlled trial the investigators want to investigate whether early versus late mobilisation after surgery in the first carpometacarpal joint (CMC1) leads to a faster recovery of hand function.
- Trial name
- NCT01679717
- Testing
- Early mobilisation after CMC1-surgery
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Study on Basal Joint Arthritis Prospective
The data in this prospective registry will be used 1) to define which surgical and nonoperative techniques are most effective at providing pain relief, restoring function, are cost effective, and patients are satisfied with their…
- Trial name
- NCT01376024
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Columbia University
Osteoarthritis of the CMC-1 Joint
TRACE - Thumb Base Replacement Arthroplasty for Osteoarthritis.
Osteoarthritis in the base of the thumb is one of the most common forms of hand arthritis. It usually appears in middle age, particularly in women, and can cause significant pain and loss of function.
- Trial name
- TRACE (NCT07178223)
- Testing
- Arthroplasty CMC-1
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Osteoarthritis of the CMC-1 Joint
Clinical Evaluation of the Articulinx InterCarpoMetacarpal Cushion (ICMC) for Osteoarthritis of the First Metacarpal Joint
This study is to evaluate the performance of the Articulinx ICMC (InterCarpoMetacarpalCushion) in the carpometacarpal joint (CMC joint) and to describe the clinical results in patients who have been treated with this device.
- Trial name
- NCT01973803
- Where
- 3 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Articulinx
Osteoarthritis Thumb
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
- Trial name
- NCT06193499
- Testing
- Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Osteoarthritis Thumb, Thumb Carpometacarpal Joint Osteoarthritis
TOUCH® CMC 1 New Enrollment US Study
The purpose of this study is to meet a PMA (P240020) condition of approval of the TOUCH® CMC 1 Prosthesis to evaluate the effectiveness and safety of the prosthesis in the United States (US) population.
- Trial name
- PAS002 (NCT07405983)
- Testing
- TOUCH® CMC 1 Prosthesis
- Where
- 4 sites in United States
- Volunteers
- 163 people
- Sponsor
- Keri Medical SA
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Use of FlexHD as Post Trapeziectomy Spacer
The objective of this study is to show that using FlexHD® (or HADM) to fill the empty space created by removal of the trapezium improves the subject's outcome and subsequent functionality of the basilar joint arthroplasty…
- Trial name
- MTF (NCT01998594)
- Testing
- Arthroplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
GraftJacket Versus Tendon Interposition for Trapeziometacarpal Osteoarthritis
Studies at the shoulder, Achilles tendon and thumb show satisfactory results regarding the use of GaftJacket. Initial trials at the thumb show, that the GraftJacket can be safely and successfully used in TMC OA surgery and…
- Trial name
- NCT01724840
- Testing
- GraftJacket, Tendon Interposition
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Schulthess Klinik
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Outcomes of Treatment for Trapeziometacarpal Osteoarthritis
The main objective of the study is the evaluation of the outcomes following treatment for TMC OA using a set of variables covering all OMERACT categories as well as the dimensions of the International Classification of…
- Trial name
- RASSH (NCT01724853)
- Testing
- Surgery, Conservative
- Where
- Switzerland
- Volunteers
- 177 people
- Sponsor
- Schulthess Klinik
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Joint Replacement or Interpositional Arthroplasty for CMC1 Arthritis, a Prospective Trial
Interpositional arthroplasty is by many considered to be the current gold standard for the treatment of thumb carpometacarpal arthritis.
- Trial name
- NCT02556515
- Testing
- Interpositional arthroplasty (Burton-Pellegrini procedure), Total joint replacement, Elektra prosthesis
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital