Clinical trials: Osteoarthritis of the Hip
Osteoarthritis, Hip, Arthritis, Degenerative
A Retro-prospective Study of Total Hip Arthroplasty With EMPERION Modular Primary Stem in Australian Centres (HISTORIC)
This is a retro-prospective, single arm, sequential enrolment study to collect relevant clinical and radiological data in at least 156 subjects, at up to 10 sites in Australia, who have been implanted with the EMPERION™ Modular…
- Trial name
- HISTORIC (NCT02435420)
- Testing
- EMPERION Modular Primary Stem
- Where
- 8 sites in Australia
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Rheumatoid Arthritis, Osteoarthritis
G7 BiSpherical Acetabular Shell PMCF Study
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for the commercially available G7 BiSpherical Acetabular Shell.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Noninflammatory Degenerative Joint Disease, Avascular Necrosis
- Trial name
- NCT03266874
- Where
- 5 sites in France, Germany and 2 more
- Volunteers
- 160 people
- Sponsor
- Zimmer Biomet
Osteoarthritis of the Hip or Knee
Dexibuprofen 400 mg Sachet Versus Ibuprofen 400 mg Sachet in Patients With Osteoarthritis of the Hip or Knee
Medical condition under investigation: Osteoarthritis of the hip or knee Number of patients planned: 480 adult patients Main objective: To evaluate and compare the tolerability profile of Dexibuprofen Gebro 400 mg powder for oral…
- Trial name
- NCT01066676
- Testing
- Dexibuprofen, Ibuprofen
- Where
- 2 sites in Austria
- Volunteers
- 482 people
- Sponsor
- Gebro Pharma GmbH
Osteoarthritis, Hip, Arthritis
Longterm-Evaluation of Vitelene® Against Standard
The purpose of this randomised prospective multicenter longterm study is to evaluate the survival rate of the implant, wear and periprosthetic osteolysis of highly cross-linked polyethylene with and without addition of Vitamin E…
- Trial name
- VITAS (NCT01713062)
- Testing
- Vitelene, XLPE
- Where
- 6 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Aesculap AG
Osteoarthritis, Hip
H-28 DELTA ST-C and Minima Retrospective Study.
The study aims to assess the clinical and radiographic outcomes of DELTA ST-C in combination with MINIMA stem at 3 years after primary THA surgery, and to evaluate the overall survivorship of the implant.
- Trial name
- NCT05014113
- Testing
- DELTA-ST cup in combination with MINIMA stem
- Where
- Greece
- Volunteers
- 95 people
- Sponsor
- Limacorporate S.p.a
Avascular Necrosis, Osteoarthritis
Zimmer Continuum Metal on Polyethylene (MoP) PostMarket Clinical Followup (PMCF) Study
This is a prospective, multi-center, non-randomized, non-controlled study designed to obtain survival and outcome data on the Continuum Metal on Polyethylene Acetabular System when used in primary total hip arthroplasty.
- Conditions
- Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Post-traumatic Arthritis
- Trial name
- NCT01307384
- Testing
- Continuum Metal on Polyethylene Acetabular System
- Where
- 2 sites in United States
- Volunteers
- 195 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee, Osteoarthritis, Hip
Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)
A study to show the safety of COV155 in patients with osteoarthritis of the knee or hip or moderate to severe chronic low back pain.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Chronic Low Back Pain
- Trial name
- NCT01722864
- Testing
- COV155
- Where
- 34 sites in United States
- Volunteers
- 153 people
- Sponsor
- Mallinckrodt
Primary Osteoarthritis, Post-Traumatic Arthritis
AVANTAGE® RELOAD Double Mobility Acetabular Cup -Clinical Study
This is a Post Marketing Clinical Follow Up study (PMCF) on the AVANTAGE RELOAD dual mobility system cup.
- Conditions
- Primary Osteoarthritis, Post-Traumatic Arthritis, Inflammatory Joint Disease, Femoral Neck Fracture
- Trial name
- NCT03357445
- Testing
- Avantage Reload cup
- Where
- 4 sites in France, Slovenia
- Volunteers
- 500 people
- Sponsor
- Zimmer Biomet
Hip Arthropathy, Hip Osteoarthritis
Post Market Clinical Follow-up of EUROSCUP Fixe Acetabular Cup
EUROSCUP Fixe is intended for use in primary and revision total hip replacement surgery. Hip replacement is intended to provide increased patient mobility and reduce pain by replacing the damages hip joint articulation in…
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Necrosis, Hip Fractures
- Trial name
- NCT05142462
- Testing
- Hip arthroplasty
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- EUROS
Osteoarthritis, Pain
Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as Monotherapy compared with placebo in participants with signs and symptoms of osteoarthritis of the hip or knee that are not…
- Trial name
- NCT02336698
- Testing
- Fulranumab 1 mg, Fulranumab 3 mg
- Where
- 32 sites in United States, Poland and 2 more
- Volunteers
- 18 people
- Sponsor
- Janssen Research & Development, LLC
Osteoarthritis, Chronic Pain
A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee
The purpose of this study is to evaluate the efficacy of Kadian NT (ALO-01) compared with placebo for treating moderate to severe chronic pain over a 12 week period.
- Trial name
- NCT00420992
- Testing
- ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release)
- Where
- 81 sites in United States
- Volunteers
- 547 people
- Sponsor
- Pfizer
Joint Pain, Knee Osteoarthritis
Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial designed to evaluate the efficacy and safety of a fixed-dose combination of celecoxib and acetaminophen compared to celecoxib monotherapy for…
- Conditions
- Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis
- Trial name
- PRECEDENT (NCT06863636)
- Testing
- Celecoxib + Acetaminophen, Celecoxib
- Where
- Mexico
- Volunteers
- 231 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Osteoarthritis
A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee
To assess the safety and tolerability of orally-administered CR845 in patients with osteoarthritis (OA) of the hip or knee. The study drug is being tested to reduce OA pain, and will be taken twice a day for two weeks, with four…
- Trial name
- NCT02524197
- Testing
- CR845 0.25 mg, CR845 0.50 mg, CR845 1 mg
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- Cara Therapeutics, Inc.
Pain, Activities of Daily Living
A Double-blind, Randomized, Parallel Group, Fase III Comparative Study With Rose Hip Powder Powder and Placebo Given to Patients With Mild to Moderate Osteoarthritis in the Knee or/and Hip
The trial is an investigator-initiated, double-blind, randomized, placebo-controlled phase III study. After the patient has receiving information about the study and after given written informed consent, the patient will be…
- Conditions
- Pain, Activities of Daily Living, Quality of Life
- Trial name
- NCT01459939
- Testing
- Rose-hip powder capsules
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hyben Vital ApS
Degenerative Joint Disease
Large Head X3 Study
The purpose of this study is to explore the benefit of X3 polyethlene inserts with larger diameter heads used in the Japanese population.
- Trial name
- NCT02543437
- Testing
- Trident Acetabular X3 Insert
- Where
- 4 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Stryker Japan K.K.
Osteoarthritis
Multi-centre Study to Assess Long-term Safety and Efficacy of the Silent™ Hip Prosthesis in Primary THR
The purpose of this study is to determine if the Silent™ hip is effective in the treatment of patients with hip joint disease requiring a total hip replacement.
- Trial name
- NCT00878046
- Testing
- DePuy Silent™ Hip femoral prosthesis
- Where
- 7 sites in Australia, France and 3 more
- Volunteers
- 108 people
- Sponsor
- DePuy International
Osteoarthritis
An Effectiveness and Safety Study of Two Doses of Acetaminophen Extended Release Caplets in the Treatment of Osteoarthritis of the Hip or Knee
The purpose of this study is to determine the safety and effectiveness of 650 mg and 1300 mg acetaminophen extended release given three times a day for the relief of signs and symptoms of osteoarthritis of the hip or knee for a…
- Trial name
- NCT00240786
- Testing
- acetaminophen extended release
- Volunteers
- 483 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Osteoarthritis of Hip
ArCom® and ArComXL® Polyethylene Data Collection
The purpose of this prospective clinical data-collection is to document the performance, clinical outcomes, and wear rates of ArCom® and ArComXL® Polyethylene.
- Trial name
- NCT00565786
- Testing
- ArCom® Polyethylene, ArComXL® Polyethylene
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee, Osteoarthritis, Hip
Efficacy and Safety of a Subcutaneous Tanezumab Titration Dosing Regimen in Subjects With Moderate to Severe Osteoarthritis of the Hip or Knee
The primary purpose of this study is to evaluate the efficacy of a titration arm of tanezumab in which treatment is started at a lower dose (2.5 mg) and increased to a higher dose (5 mg) at Week 8, compared to giving 2 doses of…
- Trial name
- NCT02697773
- Testing
- Tanezumab 2.5 mg, Tanezumab 2.5mg/5mg
- Where
- 87 sites in United States, Canada and 1 more
- Volunteers
- 698 people
- Sponsor
- Pfizer
Avascular Necrosis, Osteoarthritis
PMCF Study on the Safety and Performance of the Alloclassic Variall Cup Ceramic Bearing System in Total Hip Arthroplasty
The study is a multicenter, prospective, non-randomized, non-controlled consecutive cohort post-market clinical follow-up study.
- Conditions
- Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Posttraumatic Arthritis
- Trial name
- NCT03672370
- Where
- 2 sites in Austria
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet