Clinical trials: Osteoarthrosis
Knee Osteoarthrosis, Total Knee Arthroplasty
Patients' Experiences of Information After Total Knee Arthroplasty - A Qualitative Interview Study
The aim of this qualitative interview study is to gain new and in-depth knowledge about patients' experiences of information following total knee arthroplasty. Participants will be interviewed in the recovery phase after surgery.
- Trial name
- NCT06994884
- Where
- 2 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Vastra Gotaland Region
Knee Osteoarthrosis
Conservative Management vs. Arthroplasty in Knee Osteoarthritis
The goal of this observational study is to learn about the long-term effects of a non-surgical management programme in people with osteoarthritis that are eligible for a knee joint replacement surgery to treat their knee…
- Trial name
- NCT06623149
- Testing
- Non-Surgical Intervention, Current practice
- Where
- 6 sites in Denmark
- Volunteers
- 2,500 people
- Sponsor
- Marius Henriksen
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Study on Basal Joint Arthritis Prospective
The data in this prospective registry will be used 1) to define which surgical and nonoperative techniques are most effective at providing pain relief, restoring function, are cost effective, and patients are satisfied with their…
- Trial name
- NCT01376024
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Columbia University
Clinic Hip Osteoarthrosis
Total Hip Prosthesis Assisted by Computer
Computer assistance in prosthetic hip surgery is able to improve the accuracy of the surgery: Associating hip navigation and EOSTM imaging pre-operatively could simplify the procedure of hip navigation in lateral decubitus while…
- Trial name
- NAVEOS (NCT01613989)
- Testing
- Prosthetic hip surgery, operated under manual control, Prosthetic hip surgery operated under navigation based on EOS imaging
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Bordeaux
Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis
Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty
This long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
- Conditions
- Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis, Femur Head Necrosis, Congenital Dislocations
- Trial name
- NCT02230826
- Where
- 13 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Corin
Osteoarthrosis, Pain
A 3-Arm Study on G7 Acetabular Cup With Echo BiMetric Stem in Total Hip Arthroplasty
The study is designed to compare three articulation options in terms of osteolysis, patient satisfaction, clinical and radiographic outcomes (Oxford Hip score (OHS) and Harris Hip score (HHS) and safety.
- Conditions
- Osteoarthrosis, Pain, Arthritis
- Trial name
- NCT02518269
- Testing
- Hip Arthroplasty
- Where
- 5 sites in Denmark, Finland and 1 more
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Morbid Obesity, Hypertension
Prevention of Coronary Heart Disease in Morbidly Obese Patients
The changes in risks of developing coronary heart disease in patients with morbid obesity after different weight loss interventions have not been extensively studied.
- Conditions
- Morbid Obesity, Hypertension, Type 2 DM, Obstructive Sleep Apnea
- Trial name
- SphCor (NCT00626964)
- Testing
- Bariatric Surgery, Conservative Treatment:
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- The Hospital of Vestfold
Knee Osteoarthrosis
Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT06937528
- Testing
- Extracellular vesicles
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- University of Jordan
Osteoarthrosis, Ultrasound
Ultrasound Findings of Thumb Muscles in 1st Carpometacarpal Osteoarthritis
Carpometacarpal (CMC) joint osteoarthritis is a disorder that is estimated to affect more than one-third of postmenopausal women, leading to decreased muscle strength, reduced joint range of motion, and pain.The pathogenesis of…
- Trial name
- NCT06600464
- Testing
- Ultrasound, Assessment of Muscle Strength in Both Hands, Assessment of Pain Threshold
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Knee Osteoarthrosis
Participants With Knee Osteoarthrosis
Title: Efficacy and Safety Trial of PRP and ICQ for Elderly Women with KOA Goal: To assess if PRP and ICQ reduce symptoms and improve mobility in elderly women with knee osteoarthritis.
- Trial name
- KOA (NCT06535425)
- Testing
- Platelet-Rich Plasma, Isometric Contractions of Quadriceps, Platelet-Rich Plasma Combined with Isometric Contractions of Quadriceps
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Chengdu Sport University
Osteoarthrosis Knee Arthroplasty Analgesia Pain Management
Comparison Ultrasound-Guided Adductor Canal Block and Surgeon-Performed Block for Pain Management After Total Knee Arthroplasty
Objective: Adductor canal block (ACB) is widely performed for postoperative analgesia for total knee arthroplasty (TKA). The aim of this study is to compare surgeon-assisted and anesthesiologist-assisted (ultrasound-guided)…
- Trial name
- ACB (NCT06533085)
- Testing
- Adductor canal block by surgeon
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Osteoarthrosis
E1K Intra Articular(IA) Treatment for Knee Osteoarthritis
The objective of this study is to evaluate the efficacy and safety of pain relief treatment on knee osteoarthritis when administered E1K or placebo in patients with knee osteoarthritis aged 40 to 70 to determine the optimal dose.
- Trial name
- NCT05697952
- Testing
- E1K 1,200 ㎍/joint, E1K 2,400 ㎍/joint
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Ensol Bioscience
Osteoarthrosis of Knee, Osteoarthritis, Knee
Opening Wedge High Tibial Osteotomy
A prospective, randomised controlled trial where clinical and radiological outcome of high tibial opening wedge osteotomy with physiotherapy is compared to physiotherapy alone while treating symptomatic medial knee osteoarthrosis.
- Trial name
- OHTO (NCT03448796)
- Testing
- HTO, Supervised physiotherapeutic program
- Where
- Finland
- Volunteers
- 1 people
- Sponsor
- Kuopio University Hospital
Osteoarthrosis, ERAS
Nursing Intervention for the Reduction of Anxiety During the Process of Primary Total Hip Arthroplasty Within the Optimized Recovery Program.
Osteoarthrosis (OA) is a chronic, degenerative disease characterized by joint wear and tear. It is a major cause of pain, disability and decreased quality of life.
- Conditions
- Osteoarthrosis, ERAS, Anxiety, Nurse
- Trial name
- NIRARATC (NCT05882227)
- Testing
- video, Traditional information
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Barcelona
Osteoarthrosis of Knee
Clinical and Functional Outcome of the GEMINI SL Fixed Bearing PS Knee Prosthesis
This is a prospective, multicenter, observational study with a planned follow-up period of 10 years to confirm the safety and performance of the GEMINI SL Fixed Bearing PS knee prosthesis in longterm follow-up under routine…
- Trial name
- NCT04858347
- Testing
- Total knee replacement
- Where
- Colombia
- Volunteers
- 350 people
- Sponsor
- Waldemar Link GmbH & Co. KG
Osteoarthrosis
A Safety, Tolerability and Pharmacokinetic Dose Escalation Study of HC-ER in Patients With Osteoarthritis Pain
Assess the safety, tolerability and pharmacokinetics of multiple doses of 10, 20, 30, and 40 mg of Hydrocodone Bitartrate Extended Release (HC-ER)capsules taken with food at steady state, in subjects with chronic, moderate to…
- Trial name
- NCT02222740
- Testing
- 10 mg of Hydrocodone Bitartrate Extended Release (HC-ER), 20 mg of Hydrocodone Bitartrate Extended Release (HC-ER)
- Volunteers
- 37 people
- Sponsor
- Zogenix, Inc.
MRI, Osteoarthrosis
Osteoarthrosis on 7.0T Magnetic Resonance Imaging
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting osteoarthrosis. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater…
- Trial name
- NCT05343104
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Osteoarthrosis
Early Stability of the Delta-TT Cup With Polyethylene Insert Versus a Ceramic Insert. A RSA Study.
The goal of this study is to study the stability of the Delta-TT cup with polyethylene insert and the Delta-TT cup with ceramic insert both combined with the H-MAX femoral stem by means of RSA to assess whether the differences in…
- Trial name
- RSA-DELTA-TT (NCT03093038)
- Testing
- H-MAX stem & Delta-TT cup + polyethylene, H-MAX stem & Delta-TT cup + ceramic, C2 stem & Delta-TT cup + ceramic
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- JointResearch
Knee Osteoarthrosis
Use of Wharton Jelly Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Wharton Jelly derived Mesenchymal Stem Cells (WJMSC) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT02963727
- Testing
- Wharton Jelly derived mesenchymal stem cell
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- Hanan Jafar
Knee Osteoarthrosis
Use of Adipose Tissue Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Adipose tissue derived Mesenchymal Stem cells (ATMSC) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT02966951
- Testing
- Adipose tissue derived mesenchymal stem cell
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- Hanan Jafar