Clinical trials: Osteoarthrosis of Knee
Knee Osteoarthrosis, Total Knee Arthroplasty
Patients' Experiences of Information After Total Knee Arthroplasty - A Qualitative Interview Study
The aim of this qualitative interview study is to gain new and in-depth knowledge about patients' experiences of information following total knee arthroplasty. Participants will be interviewed in the recovery phase after surgery.
- Trial name
- NCT06994884
- Where
- 2 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Vastra Gotaland Region
Knee Osteoarthrosis
Conservative Management vs. Arthroplasty in Knee Osteoarthritis
The goal of this observational study is to learn about the long-term effects of a non-surgical management programme in people with osteoarthritis that are eligible for a knee joint replacement surgery to treat their knee…
- Trial name
- NCT06623149
- Testing
- Non-Surgical Intervention, Current practice
- Where
- 6 sites in Denmark
- Volunteers
- 2,500 people
- Sponsor
- Marius Henriksen
Knee Osteoarthrosis
Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT06937528
- Testing
- Extracellular vesicles
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- University of Jordan
Knee Osteoarthrosis
Participants With Knee Osteoarthrosis
Title: Efficacy and Safety Trial of PRP and ICQ for Elderly Women with KOA Goal: To assess if PRP and ICQ reduce symptoms and improve mobility in elderly women with knee osteoarthritis.
- Trial name
- KOA (NCT06535425)
- Testing
- Platelet-Rich Plasma, Isometric Contractions of Quadriceps, Platelet-Rich Plasma Combined with Isometric Contractions of Quadriceps
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Chengdu Sport University
Osteoarthrosis Knee Arthroplasty Analgesia Pain Management
Comparison Ultrasound-Guided Adductor Canal Block and Surgeon-Performed Block for Pain Management After Total Knee Arthroplasty
Objective: Adductor canal block (ACB) is widely performed for postoperative analgesia for total knee arthroplasty (TKA). The aim of this study is to compare surgeon-assisted and anesthesiologist-assisted (ultrasound-guided)…
- Trial name
- ACB (NCT06533085)
- Testing
- Adductor canal block by surgeon
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Osteoarthrosis of Knee, Osteoarthritis, Knee
Opening Wedge High Tibial Osteotomy
A prospective, randomised controlled trial where clinical and radiological outcome of high tibial opening wedge osteotomy with physiotherapy is compared to physiotherapy alone while treating symptomatic medial knee osteoarthrosis.
- Trial name
- OHTO (NCT03448796)
- Testing
- HTO, Supervised physiotherapeutic program
- Where
- Finland
- Volunteers
- 1 people
- Sponsor
- Kuopio University Hospital
Osteoarthrosis of Knee
Clinical and Functional Outcome of the GEMINI SL Fixed Bearing PS Knee Prosthesis
This is a prospective, multicenter, observational study with a planned follow-up period of 10 years to confirm the safety and performance of the GEMINI SL Fixed Bearing PS knee prosthesis in longterm follow-up under routine…
- Trial name
- NCT04858347
- Testing
- Total knee replacement
- Where
- Colombia
- Volunteers
- 350 people
- Sponsor
- Waldemar Link GmbH & Co. KG
Knee Osteoarthrosis
Use of Wharton Jelly Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Wharton Jelly derived Mesenchymal Stem Cells (WJMSC) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT02963727
- Testing
- Wharton Jelly derived mesenchymal stem cell
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- Hanan Jafar
Knee Osteoarthrosis
Use of Adipose Tissue Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Adipose tissue derived Mesenchymal Stem cells (ATMSC) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT02966951
- Testing
- Adipose tissue derived mesenchymal stem cell
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- Hanan Jafar
Osteoarthritis, Knee, Osteoarthrosis of Knee
Univation XM France
The study is set up due to regulatory purposes and to collect routine clinical data of the mobile-bearing implant univation XM. The study is designed as a prospective follow-up study with a historic patient cohort who have been…
- Conditions
- Osteoarthritis, Knee, Osteoarthrosis of Knee, Arthritis Knee, Unicompartmental Knee Arthroplasty
- Trial name
- NCT04199481
- Where
- France
- Sponsor
- Aesculap AG
Osteoarthritis, Joint Disease
Autologous Adipose-Derived Stromal Vascular Fraction Cells for Osteoarthritis Treatment
Adipose-derived stromal vascular fraction cells (SVFs) include regenerative cell populations (hematopoietic cells, pericytes, endothelial cells and progenitors, stromal/stem cells) and thus are potentially important as new…
- Conditions
- Osteoarthritis, Joint Disease, Osteoarthritis,Knee, Arthritis, Degenerative
- Trial name
- NCT02967874
- Testing
- Intra-articular auto-SVFs injection, Hyaluronic Acid
- Where
- Russia
- Volunteers
- 27 people
- Sponsor
- Russian Academy of Medical Sciences
Osteoarthrosis, Knee
Total Knee Replacement With the Attune vs. the Press Fit Condylar (PFC) Sigma.
100 knees with primary osteoarthritis and scheduled for a total knee replacement (TKR) will be recruited from our waiting list. The patients will be randomized to become operated with the Attune or PFC total knee arthroplasty.
- Trial name
- Att16SM (NCT03077958)
- Testing
- Total Knee Replacement (2 different design)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Osteoarthritis, Osteoarthritis, Knee
Intraoperative Liposomal Bupivacaine Injection in Primary Total Knee Arthroplasty
The purpose of the study is to evaluate the efficacy of local infiltration of liposomal bupivacaine versus use of an indwelling femoral peripheral nerve block in controlling early postoperative pain in primary total knee…
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Arthritis, Degenerative, Osteoarthrosis
- Trial name
- NCT02341079
- Testing
- Bupivacaine Liposome Injection, Indwelling femoral nerve block
- Where
- United States
- Sponsor
- United States Naval Medical Center, San Diego
Knee Osteoarthrosis
Treatment of Knee Arthrosis With Platelet-derived Growth Factors vs. Hyaluronic Acid.
Primary aim of this trial was to assess efficacy three intraarticular injections of platelet lysate when compared to hyaluronic acid.
- Trial name
- NCT02958761
- Testing
- intraarticular injections of platelet lysate, hyaluronic acid
- Volunteers
- 58 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Knee Joint Osteoarthrosis, Hyperalgesia
Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty
Despite improvements in analgesic treatment following total knee arthroplasty (TKA) for osteoarthrosis, a substantial part of patients still have severe acute pain after surgery.
- Conditions
- Knee Joint Osteoarthrosis, Hyperalgesia, Severe Movement Related Pain
- Trial name
- NCT02253966
- Testing
- Methylprednisoloneacetate, Lidocaine, sodium chloride
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet