Clinical trials: Osteopenia, Generalized
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function and Bone
This study is an ancillary study to the Utilizing Protein During Weight Loss to Impact Physical Function (UPLIFT) trial (NCT03074643) to evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT-Bone (NCT03819478)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Osteopenia, Osteoporosis
Time-specific Exercise in Circadian Context
The project aims to explore the mechanisms, by which physical activity can support healthy ageing and decrease the negative impact of ageing on the circadian system, musculoskeletal system and immunity.
- Conditions
- Osteopenia, Osteoporosis, Aging
- Trial name
- CAEx (NCT06746649)
- Testing
- Combined training
- Where
- Slovakia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Comenius University
Osteoporosis, Osteopenia
Melatonin-Micronutrients for Osteopenia Treatment Study
The investigators' long-term goal is to employ novel methods to improve bone formation and bone density in women (and men) with osteopenia or osteoporosis while also decreasing signs and symptoms of degenerative joint and disc…
- Trial name
- MOTS (NCT01870115)
- Testing
- Fiber Pill, Melatonin, Strontium citrate, Vitamins D3 and K2
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Breast Cancer, Osteoporosis
Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
RATIONALE: Zoledronate may reduce bone loss in patients receiving letrozole for breast cancer. PURPOSE: This clinical trial is studying how well zoledronate works in treating osteopenia or osteoporosis in postmenopausal women…
- Trial name
- NCT00436917
- Testing
- zoledronic acid, Letrozole as adjuvant therapy
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Osteoporosis, Osteopenia, Osteoporosis, Postmenopausal
Effects of Vitamin D Supplementation in Muscle Strength and Balance Training
Introduction: In Brazil, a person who is sixty years old or more is considered elderly. The incidence of osteoporosis and osteopenia has been increasing, as have fractures resulting from falls.
- Trial name
- NCT03367585
- Testing
- Physical exercise + Vitamin D3, Physical exercise
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Osteopenia
Study of the Effect of Once a Week Risedronate on the Microstructure of Tibia and Radius Using a New Scanning Method
The primary purpose of the protocol is to evaluate the sensitivity of 3D-pQCT (3D-Peripheral Quantitative Computed Tomography) technology to detect minute changes in bone microarchitecture.
- Trial name
- NCT00386360
- Testing
- risedronate
- Where
- 9 sites in Argentina, Australia and 5 more
- Volunteers
- 161 people
- Sponsor
- Warner Chilcott
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Osteoporosis, Osteopenia
Hormonal and Bone Turnover Marker Response to an Acute Bout of Resistance or Plyometric Exercise
We are interested in determining if there exist a short-term response in the serum markers and hormones that participate in the regulation of bone tissue formation and breakdown to a single, high-intensity exercise session of…
- Trial name
- NCT00572871
- Testing
- plyometric exercise, resistance exercise, No exercise
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Osteoporosis, Osteopenia
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
The purpose of this study is to determine whether in postmenopausal women with low bone mineral density, the mean percent change in total hip BMD in subjects receiving denosumab is not less than that observed in subjects…
- Trial name
- NCT00330460
- Testing
- Alendronate, Denosumab
- Volunteers
- 1,189 people
- Sponsor
- Amgen
Osteoporosis, Fractures
Determination of Optimum Age for DXA Screening for Osteoporosis in HIV - The Probono 1 Study
The purpose of this study is to determine the bone mineral density in male and female patients with HIV infection according to age groups.
- Conditions
- Osteoporosis, Fractures, HIV Infection
- Trial name
- Probono1 (NCT01669954)
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- King's College London
Urolithiasis, Renal Colic
Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia
Patients suffering from acute renal colic are evaluated by non contrast computerized tomography with excellent identification rates of urinary stones.
- Conditions
- Urolithiasis, Renal Colic, Osteopenia
- Trial name
- NCT04080973
- Testing
- CT scan, 24 hour urine collection
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Ziv Hospital
Obesity, Osteopenia
Study of Growth Hormone and Bone in Obesity
Obesity is an important risk factor for osteoporosis and fractures. With the growing prevalence of obesity in the U.S., understanding the pathophysiology of bone loss in this population is of importance to public health.
- Trial name
- NCT01724489
- Testing
- Growth hormone
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoporosis, Osteopenia
Models of Primary Osteoporosis Screening in Male Veterans
Models of Osteoporosis Screening in Male Veterans aims to test 1 distinct care model of primary osteoporosis screening in men within the VA healthcare setting.
- Conditions
- Osteoporosis, Osteopenia, Osteoporotic Fracture
- Trial name
- MOPS (NCT04079868)
- Testing
- Bone Health Service Model
- Where
- 3 sites in United States
- Volunteers
- 3,512 people
- Sponsor
- VA Office of Research and Development
Breast Cancer, Menopause
Study to Assess Efficacy of Risedronate in Preventing Bone Loss in Postmenopausal Women Treated for Breast Cancer
Aromatase inhibitor therapy is in France the adjuvant reference treatment for postmenopausal women with early-stage breast cancer. This treatment induces bone loss and a higher risk of fractures.
- Conditions
- Breast Cancer, Menopause, Osteopenia
- Trial name
- RISAROS (NCT00859703)
- Testing
- Risedronate
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Chronic Disease, Frail
Functional Exercise and Nutrition Education Program for Older Adults
There is strong evidence that specific types of exercise can improve health and physical function in older adults. While community exercise classes exist, many older adults with chronic conditions may need guidance from…
- Conditions
- Chronic Disease, Frail, Diabetes Mellitus, Cancer
- Trial name
- MoveStrong (NCT04037436)
- Testing
- Strength and Balance Training & Nutrition Education, Usual Care
- Where
- 5 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Waterloo
Sarcopenia, Osteopenia
Exercise Effects on Sarco-Osteopenia in Older Men
The study determined the effects of predominately resistance type exercise in combination with protein supplements on parameters of sarcopenia and osteopenia (sarco-osteopenia) in older, community dwelling men with sarcopenia and…
- Trial name
- NCT03453463
- Testing
- exercise
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Postmenopausal Osteoporosis, Postmenopausal Osteopenia
The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation
This study is a prospective, multicenter, open-label, randomized non-inferiority trial comparing intravenous ibandronate and zoledronic acid as sequential therapy after denosumab discontinuation in postmenopausal women with…
- Conditions
- Postmenopausal Osteoporosis, Postmenopausal Osteopenia, Primary Osteoporosis, Osteoporosis
- Trial name
- NCT07406685
- Testing
- Ibandronate IV, Zoledronic acid IV
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- National Taiwan University Hospital
Osteopenia
Effect of Whole-Body Vibration on Plasma Sclerostin Level
The aim of this study is to investigate effect of whole-body vibration on plasma sclerostin level in healthy young adult women. Fifteen healthy young adult women are planned to include in this study.
- Trial name
- WBV-SCL (NCT01310335)
- Testing
- whole-body vibration (WBV)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Low Bone Density, Osteopenia
A Taiwan Isoflavone Multicenter Study (TIMS)
Consumption of soy-based foods is associated with a number of health benefits, including lower risk of cardiovascular disease, breast and prostate cancer, attenuated menopausal symptoms and prevention of bone loss with age.
- Trial name
- NCT00262184
- Testing
- Soy Isoflavone
- Where
- 3 sites in Taiwan
- Volunteers
- 420 people
- Sponsor
- National Health Research Institutes, Taiwan
Osteoporosis, Chronic Respiratory Disease
Collaborative Care With Smart Health Management Program for Patients With Chronic Illness
This study verifies efficacy of collaborative care with Smart Health Management Program developed for patients with chronic illness.
- Conditions
- Osteoporosis, Chronic Respiratory Disease, Arthritis, Osteopenia
- Trial name
- NCT03294057
- Testing
- Tele-coaching programs, ICT programs, A book about chronic disease
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital