Clinical trials: Osteoporosis Risk
Osteoporosis
Risk-stratified Osteoporosis Strategy Evaluation Study (ROSE)
The Risk-stratified Osteoporosis Strategy Evaluation Study (ROSE) is a randomised population-based study, including 20,904 Danish women aged 65-80 years, investigating the effectiveness of a two-step screening programme for…
- Trial name
- ROSE (NCT01388244)
- Testing
- Screening, Control
- Where
- Denmark
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL
Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
This project will examine habitual physical activity, bone health, and insulin resistance in pediatric acute lymphocytic leukemia (ALL) and lymphoma cancer survivors at two time points: baseline and 6 months.
- Conditions
- Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL, Pediatric Lymphoma, Bone Loss
- Trial name
- HBHL (NCT04472286)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Osteoporosis, Age-Related, Osteoporosis Risk
A Culinary Intervention for Bone Health
This is a randomized, controlled pilot study to evaluate the feasibility and acceptability of a single 2-hour culinary medicine intervention for bone health among individuals with age-associated low bone mass.
- Trial name
- NCT05197244
- Testing
- Culinary Medicine Intervention
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Menopause, Postmenopausal Bone Loss
Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy
Women undergoing surgical menopause often experience marked menopausal side effects but are reluctant to use estrogen or other female hormones to ease the transition to menopause because of worries that the hormones may increase…
- Conditions
- Menopause, Postmenopausal Bone Loss, Breast Cancer
- Trial name
- NCT00165204
- Testing
- Tibolone
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Dana-Farber Cancer Institute
Osteoporosis
Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL)
The purpose of the study is to determine the safety and effectiveness of 2 doses of the investigational drug, lasofoxifene, compared to placebo (an inactive substance) in reducing new spinal fractures in women with osteoporosis.
- Trial name
- PEARL (NCT00141323)
- Testing
- lasofoxifene
- Where
- 201 sites in United States, Argentina and 30 more
- Volunteers
- 8,556 people
- Sponsor
- Ligand Pharmaceuticals
Osteoporosis, Fracture
Mobile Device to Help FRAX® Screening
Background: The Taiwanese FRAX® (Fracture Risk Assessment Tool) calculator is available online for clinical use. Our Taiwanese Osteoporosis Clinical Treatment Guidelines suggests using the American high risk cut-points for…
- Trial name
- NCT01930656
- Where
- Taiwan
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus, Diabetes Mellitus, Type 1
Awareness of Osteoporosis in Diabetes Mellitus Patients
Osteoporosis is a condition that describes compromised skeletal microarchitecture in general, with clinical signs of decreased bone mineral density. Diabetes mellitus patients are at increased risk for developing osteoporosis.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Osteoporosis
- Trial name
- NCT05760118
- Testing
- Patient Participation Form
- Volunteers
- 400 people
- Sponsor
- Uskudar State Hospital
Osteoporosis, With or Without Treatment, Bisphosphonate Treatment
Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
Bisphosphonates are drugs that prevent bone loss by blocking the activity of cells that normally resorb bone. The most common examples of these drugs are Boniva and Fosamax.
- Conditions
- Osteoporosis, With or Without Treatment, Bisphosphonate Treatment, Atypical Femur Fracture, Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ)
- Trial name
- NCT01875458
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Osteoporosis, Risk of Falls
EFFECTIVENESS AND CLINICAL OPTIMIZATION OF A STANDARDIZED PHYSIOTHERAPY EXERCISE PROGRAM TARGETING BALANCE-POSTURE INTERACTION AND FALL RISK IN OSTEOPOROSIS: A RANDOMIZED CONTROLLED TRIAL
Osteoporosis is a systemic disorder of the skeletal system characterized by decreased Bone Mass and deterioration of the Microarchitecture, making it significantly easier to fracture the bones.
- Conditions
- Osteoporosis, Risk of Falls, Rehabilitation
- Trial name
- EFFECTIVENESS (NCT07763717)
- Testing
- Structured Physiotherapy Exercise Program
- Where
- Kosovo
- Volunteers
- 88 people
- Sponsor
- Alma Mater Europaea - Slovenia
Osteoporosis, Fracture
Imaging Parameters to Predict Future Vertebral Fracture in Osteoporosis
After vertebroplasty, many patients will suffer from 2nd fracture in the vertebral column. With analyzing of the images done right after the 1st vertebroplasty, we can define the parameters from different imaging and they can be…
- Trial name
- NCT01653873
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Osteoporosis, Osteoporosis Risk
Risk of Osteoporotic Fracture in Home Care Patients in Turkey
This study will assess the incidence of osteoporosis and osteoporotic fracture risk of registered home health patients in the Anatolian side of Istanbul.
- Conditions
- Osteoporosis, Osteoporosis Risk, Osteoporotic Fractures
- Trial name
- NCT05738785
- Testing
- Document review and scanning
- Where
- Turkey (Türkiye)
- Volunteers
- 370 people
- Sponsor
- Uskudar State Hospital
Osteoporosis
Artificial Intelligence-Guided Diagnosis for High-Risk Osteoporosis Populations: A Pragmatic Randomized Clinical Trial
Project Summary I. Project Objectives With the rapid advancement of medical technology, smart medical devices have become one of the key components of modern healthcare.
- Trial name
- NCT07620834
- Testing
- VeriOsteo OP
- Where
- 3 sites in Taiwan
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Sarcoidosis, Osteoporosis Risk
Bone Mineral Density in Patients With Sarcoidosis
To assess the frequency and risk factors of decreased bone mineral density (BMD) and vertebral fractures in Danish patients with sarcoidosis.
- Trial name
- NCT06238037
- Where
- Denmark
- Volunteers
- 144 people
- Sponsor
- University of Aarhus
Osteoporosis, Accidental Falls
The Effect of Digital Education for Osteoporosis Patients on Fracture Risk and Related Health Outcomes.
A digital education for osteoporosis patients (DEOP) has been developed and tested on patients in Region Vastra Gotaland, Sweden.
- Conditions
- Osteoporosis, Accidental Falls, Fractures, Bone, Patient Reported Outcome Measures
- Trial name
- NCT06603545
- Testing
- Digital education for osteoporosis patients
- Volunteers
- 2,640 people
- Sponsor
- Sahlgrenska University Hospital
Healthy, Osteopenia
Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-preFX (NCT06567054)
- Testing
- Measurements with the POROUS R3C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine, DXA-based Vertebral Fracture Assessment (VFA)
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Sarcopenia, Falls Patient
Sarcopenia and Risk of Fall in Osteoporotic Postmenopausal Women
The main scope of the present pilot study is to evaluate the possible association between the status of sarcopenia and the risk of fall in osteoporotic postmenopausal women.
- Conditions
- Sarcopenia, Falls Patient, Osteoporosis, Postmenopausal
- Trial name
- Sarcopenia (NCT03382366)
- Testing
- Blood sampling, risk of fall evaluation, and MR acquisition.
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Chronic Obstructive Pulmonary Disease, Osteoporosis
Case Control Study: Determinants of Osteoporosis in GOLD II COPD Patients.
Patients with COPD have been found to have an increased risk of osteoporosis. The underlying mechanism is not clear yet. This case control study aims to identify risk factors for osteoporosis in GOLD II COPD patients.
- Trial name
- NCT00725673
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Osteoporosis
Analysis of Bone Micro-Architecture as a Clinical Biomarker for Image-Based Fracture Risk Estimation.
Osteoporosis is a common disease among elderly people, which leads to an increased bone fracture risk. Bone fractures can greatly reduce quality of life and increase age-related problems including reduced life expectancy.
- Trial name
- NCT03463850
- Testing
- Dual Energy CT (DECT), DEXA
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- State University of New York - Upstate Medical University
Fall Injury, Hip Fractures
Fall, Fracture and Frailty
This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation.
- Conditions
- Fall Injury, Hip Fractures, Risk Reduction, Osteoporosis, Osteopenia
- Trial name
- FFF (NCT05712252)
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Region Skane
Osteoporosis
Bone UltraSonic Scanner (BUSS) Clinical Optimization Study
The aim of this clinical study using Bone UltraSonic Scanner (BUSS) is to obtain clinical data which will help to optimize the BUSS examination procedure and its diagnostic algorithms for assessment of bone conditions.
- Trial name
- BUSS (NCT01056432)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories