Clinical trials: Osteoporosis Risk
Osteoporosis, Fracture
Osteoporosis and Fall Prevention High Risk Population Intervention and Follow up in the Metropolitan Area
BACKGROUND: The deterioration of musculoskeletal system imposes significant impact on physical activity in older adults. METHODS: This was a randomized, parallel-group, prospective study.
- Trial name
- NCT02608749
- Testing
- Integrated care (IC), Lower extremity exercise (LEE), Home care (HC)
- Where
- Taiwan
- Volunteers
- 151 people
- Sponsor
- National Taiwan University Hospital
Hyperemesis Gravidarum
Hyperemesis Gravidarum and Osteoporosis
Hyperemesis Gravidarum (HG) is a common disorder for hospitalization in the first trimester of pregnancy and related to protracted vomiting and nausea. It can be accompanied by ketonuria, dehydration and weight loss.
- Trial name
- NCT03127293
- Testing
- DEXA
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Adana Numune Training and Research Hospital
Periodontal Diseases, Diabetes
Genomic Determinants and Shared Genetic Pathways of Periodontal Disease
Despite significant improvement in treating periodontal disease (PD) and the identification of multiple risk factors, little is known about the specific contribution of genetics to PD pathogenesis.
- Conditions
- Periodontal Diseases, Diabetes, Osteoporosis, Cardiovascular Risk Factor
- Trial name
- NCT03437798
- Testing
- Disease status
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Tufts University
Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL
Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
This project will examine habitual physical activity, bone health, and insulin resistance in pediatric acute lymphocytic leukemia (ALL) and lymphoma cancer survivors at two time points: baseline and 6 months.
- Conditions
- Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL, Pediatric Lymphoma, Bone Loss
- Trial name
- HBHL (NCT04472286)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Breast Cancer, Metastatic Breast Cancer (MBC)
A Study of Romosozumab in People With Breast Cancer and Osteoporosis
The researchers are doing this study to see if romosozumab is effective at helping with bone formation in people with metastatic breast cancer (MBC) that has spread to the bones. All participants will have osteoporosis.
- Trial name
- NCT07776613
- Testing
- Romosozumab
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Esophageal Cancer, Squamous Cell Carcinoma
Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of Osteoporosis (MK-0217A-352)
This is a 2-phase retrospective database study, using both case-cohort and inception (intention-to-treat) cohort analyses to evaluate any association between oral treatments for osteoporosis and the risk of esophageal cancer in…
- Conditions
- Esophageal Cancer, Squamous Cell Carcinoma, Adenocarcinoma
- Trial name
- NCT01077817
- Testing
- Alendronate, Etidronate, Ibandronate
- Volunteers
- 684,815 people
- Sponsor
- Organon and Co
Bone Density, Osteopenia
Evaluation of Bone Mineral Density Indications and Outcomes in Female Adolescents: Implications for Early Detection of Osteopenia/Osteoporosis and Gynecologic Practice
This retrospective study evaluates bone mineral density (BMD) measurements obtained by dual-energy X-ray absorptiometry (DEXA) in adolescent girls aged 12 to 21 years at a tertiary care center.
- Conditions
- Bone Density, Osteopenia, Amenorrhea, Primary Amenorrhea
- Trial name
- TEEN-BMD (NCT07164248)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bagcilar Training and Research Hospital
Health Belief Model-Based Osteoporosis Education Programme
OSTEOPOROSIS EDUCATION AND ITS IMPACT ON OSTEOPOROSIS HEALTH BELIEFS AND AWARENESS IN WOMEN AT RISK OF OSTEOPOROSIS
Osteoporosis is a significant public health problem characterized by low bone mass and deterioration in the microarchitecture of bone tissue, leading to an increased risk of fractures.
- Trial name
- HBM-osteo-edu (NCT07486076)
- Testing
- Osteoporosis Education Based on the Health Belief Model
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Osteoporosis
Study of Male Osteoporosis and Aging
The aim of this study is to identify potential risk factors for fragility fractures in men.
- Trial name
- NCT00463411
- Where
- Denmark
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Vitamin D Status, Glucose Tolerance
Vitamin D Retrospective Study and Role With Disease
Vitamin D deficiency is associated with a heightened risk for developing type 2 diabetes, hypertension, and osteopenia/osteoporosis.
- Conditions
- Vitamin D Status, Glucose Tolerance, Blood Pressure, Bone Mineral Density
- Trial name
- NCT01798030
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Osteoporosis Risk, Osteoporosis, Postmenopausal
Evaluation of Osteo-Buddy in Improving Osteoporosis Knowledge
This is a pilot randomised controlled trial (RCT) to evaluate the use of a Virtual Health Assistant (VHA) named Osteo-Buddy in improving the knowledge of osteoporosis in older women.
- Trial name
- NCT07034131
- Testing
- Osteo-Buddy, Usual Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- SingHealth Polyclinics
Stroke, Osteoporosis
Assessment and Comparison of Osteoporosis Risk Factors After Stroke
The aim of this study is to evaluate the effects of stroke and associated clinical, functional, nutritional, and muscular factors, including handgrip strength, on bone mineral density and osteoporosis by comparing patients with…
- Trial name
- NCT07228611
- Testing
- Bone Mineral Density
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Osteoporosis
Risk-stratified Osteoporosis Strategy Evaluation Study (ROSE)
The Risk-stratified Osteoporosis Strategy Evaluation Study (ROSE) is a randomised population-based study, including 20,904 Danish women aged 65-80 years, investigating the effectiveness of a two-step screening programme for…
- Trial name
- ROSE (NCT01388244)
- Testing
- Screening, Control
- Where
- Denmark
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hip Fractures
Dietary Patterns and Hip Fracture Risk in the UK Biobank
Hip fracture is a common serious injury in older adults that reduces mobility, independence, and quality of life, and can lead to premature death.
- Trial name
- NCT05554549
- Testing
- Dietary pattern observed
- Where
- United Kingdom
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Osteoporosis
Improving Management of Patients at High Risk for Osteoporotic Fractures (0000-038)
The purpose of this study is to assess the impact of disease management interventions on percent receiving a bone densitometry test and percent appropriately prescribed a medication for osteoporosis.
- Trial name
- NCT00139438
- Testing
- Disease Management Assessment
- Volunteers
- 4,266 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoporosis, Metabolic Syndrome
Body Composition and Risk for Development of Pre-diabetes in Post-menopausal Chinese Women in Singapore
This project aims to ascertain that novel imaging and metabolic markers can be used to identify as well as to validate and improve the detection of Singapore-Chinese women at increased risk of diabetes.
- Trial name
- NCT03503552
- Where
- Singapore
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- JeyaKumar Henry
Improving the Early Diagnosis of Osteoporosis in Adults and Children Living in the Abay Region of Kazakhstan
Identification and Assessment of Risk Factors for the Development of Osteoporosis in Adults and Children Living in the Abay Region of the Republic of Kazakhstan Using the Method of Dual-energy X-ray Absorptiometry and Clinical and Epidemiological Research
A survey of people to identify risk factors for osteoporosis, which include age, gender, lifestyle, diet, physical activity, the presence or absence of somatic pathology.
- Trial name
- NCT06344598
- Where
- Kazakhstan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Semey State Medical University
Hip Fracture (First Incidence of)
Diet and Hip Fracture Risk in the United Kingdom Women's Cohort
Hip fracture is a common serious injury in older women that reduces quality of life and can lead to premature death. In the United Kingdom, hip fractures are estimated to account for 1.5 million hospital bed days used per year…
- Trial name
- NCT05081466
- Testing
- Dietary pattern, Fruit and vegetable intake, Meat intake
- Where
- United Kingdom
- Volunteers
- 35,372 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Osteoporosis, Bladder Disease
Osteoporosis, Trabecular Bone Score and Fracture Risk Assessment in Male Patients After Radical Cystectomy
Radical cystectomy (RC) with ileal urinary diversion (UD) is a standard treatment for muscle-invasive bladder cancer. However, emerging evidence indicates that this procedure may significantly impact bone health.
- Trial name
- NCT04153227
- Testing
- Bone mineral density (BMD), Trabecular bone score (TBS), Fracture risk Assessment Tool (FRAX)
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- Corporacion Parc Tauli
Osteoporosis Risk, Osteoporosis
OsteoPorosis Treatment Identification Using Machine Learning
OPTIMAL is a pilot feasibility study for a machine learning (ML) based enhanced screening software for osteoporosis. This tool has been created using machine learning, based on data from NHS Greater Glasgow and Clyde.
- Trial name
- OPTIMAL (NCT05678569)
- Testing
- Dual Energy Xray Absorptiometry
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde