Clinical trials: Osteoporosis Risk
Postmenopausal Osteoporosis
A Study of MK-0822 in Postmenopausal Women With Osteoporosis to Assess Fracture Risk (MK-0822-018)
The purpose of the event-driven base study is to determine the safety and efficacy, especially fracture risk reduction, of odanacatib in postmenopausal women diagnosed with osteoporosis.
- Trial name
- NCT00529373
- Testing
- Odanacatib, Vitamin D3, Calcium carbonate
- Volunteers
- 16,071 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoporosis, Postmenopausal, Osteoporotic Fractures
Evaluation of a Decision Analysis Model in the DASH-Osteo Decision Aid.
Fragility fractures, often caused by low bone mineral density, are a major health concern for postmenopausal women. One way to prevent these fractures is by taking medication, but deciding whether to start treatment can be…
- Conditions
- Osteoporosis, Postmenopausal, Osteoporotic Fractures, Diphosphonates, Fracture Risk Assessment
- Trial name
- DASH-Osteo (NCT07120854)
- Testing
- Decision aid with decision analysis model, Decision aid alone, Usual Care
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Female Osteoporosis
Female Osteoporosis
The aim of this study is to compare the Osteoporosis Risk Assessment Tool and the Osteoporosis Self-Assessment Tool with the gold standard DEXA in determining the risk of osteoporosis in the lumbar and femoral regions in female…
- Trial name
- OST and ORAI (NCT07402772)
- Volunteers
- 1,500 people
- Sponsor
- Kayseri City Hospital
Osteoporosis, Sarcopenia
Comprehensive Risk Assessment and Prevention Plan of Osteoporosis and Sarcopenia for the Elderly Participating in Community-based Long-term Care Services
The purpose of this project is: 1. Provide the epidemiological data of the prevalence, incidence, and risk factors of osteoporosis and sarcopenia among the elderly in rural areas. 2.
- Conditions
- Osteoporosis, Sarcopenia, Frailty
- Trial name
- NCT05104034
- Testing
- Osteoporosis screening and treatment as needed, Sarcopenia, Exercise
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Osteoporosis, Postmenopausal Osteoporosis
Study to Evaluate the Safety and Efficacy of BA058 (Abaloparatide) for Prevention of Fracture in Postmenopausal Women
The purpose of this study is to determine whether BA058 (abaloparatide), a parathyroid hormone-related peptide, is effective in preventing fractures in postmenopausal women with severe osteoporosis who are at risk of fractures.
- Trial name
- ACTIVE (NCT01343004)
- Testing
- BA058 80 mcg, teriparatide
- Where
- 28 sites in United States, Argentina and 8 more
- Volunteers
- 2,463 people
- Sponsor
- Radius Health, Inc.
Women, Osteoporosis
Temporomandibular Disorders and Osteoporosis
Increased life expectancy has attracted research attention, interested in provide a quality and healthy aging. According to the latest census conducted in 2010 by IBGE, Brazilian population consists of 97,342,162 women, whom…
- Conditions
- Women, Osteoporosis, Osteopenia, Temporomandibular Disorder
- Trial name
- TMDOST (NCT01029210)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Prevent Osteoporosis and Osteoporotic Fractures, Improve Quality of Life
BREAST CANCER AND EXERCISE
A Finnish Breast Cancer Group Study (BREX 01-2004). A multicenter phase III open randomised trial of the efficacy of exercise in the prevention of long-term adverse effects of adjuvant treatments and breast cancer recurrences in…
- Conditions
- Prevent Osteoporosis and Osteoporotic Fractures, Improve Quality of Life, Improve Weight Control, and Muscular and Cardiovascular Fitness, Help the Patients to Return to Working Life
- Trial name
- BREX (NCT00639210)
- Testing
- supervised training
- Where
- Finland
- Volunteers
- 573 people
- Sponsor
- Finnish Breast Cancer Group
Healthy, Osteopenia
Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal Women
The aim of the present clinical trial is to examine the effects of everolimus, resistance training, or their combination on bone and muscle health formation in elderly women aged 60-75 years.
- Conditions
- Healthy, Osteopenia, Osteoporosis Risk
- Trial name
- StrongBone (NCT07191353)
- Testing
- Everolimus, Resistance training
- Where
- 2 sites in Denmark
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Chronic Kidney Diseases, Hyperparathyroidism, Secondary
Analysis of Bone Microarchitecture With HR-pQCT of Patients With Chronic Kidney Disease (CKD) Candidates for Renal Transplantation
While the duration of renal transplant function has increased over the last decade kidney transplanted patients (KTP) still exhibit a fracture risk 4 times higher than in the general population.
- Trial name
- TRANSBONE (NCT02523209)
- Testing
- HR-pQCT, DEXA
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Osteoporosis, Cardiovascular Risk Factor
Effects of a 12-week Home-based Yoga on Bone and Cardiovascular Health
While effects of specific exercise interventions on bone and CVD in postmenopausal women have been demonstrated and evaluated, the effects of randomized controlled exercise interventions, particularly in middle-aged premenopausal…
- Trial name
- NCT04353700
- Testing
- Yoga group
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Osteopenic Women
Bone Quality Lyon Orleans
QUALYOR is a prospective study on the predictive value for fragility fracture of various new techniques assessing bone quality, among postmenopausal women with low bone mass.
- Trial name
- QUALYOR (NCT01150032)
- Testing
- Bone quality complementary exams
- Where
- 2 sites in France
- Volunteers
- 1,605 people
- Sponsor
- Hospices Civils de Lyon
Osteoarthritis Hand, Lumbago
Cardiovascular Risk in Digital Osteoarthritis
The goal of this cross-sectional case control study is to investigate the cardiovascular risk in digital osteoarthritis. This study aims to compare the cardiovascular risk between group of patients with digital osteoarthritis and…
- Conditions
- Osteoarthritis Hand, Lumbago, Osteoporosis, Radiculopathy Lumbar
- Trial name
- RICARDI (NCT05923736)
- Testing
- Intima media thickness ultrasound, hand ultrasound, EndoPAT™ 2000 system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoporosis, Sarcopenia
Evaluation of Balance and Functionality in Postmenopausal Osteoporosis Using Quadriceps Femoris Muscle Thickness, Beyond Thoracic Hyperkyphosis
To determine the impact of thoracic hyperkyphosis, sarcopenia and quadriceps muscle thickness evaluated by ultrasonography (USG) on balance, fall risk and functional parameters in women with postmenopausal osteoporosis, to assess…
- Conditions
- Osteoporosis, Sarcopenia, Ultrasonography, Hyperkyphosis
- Trial name
- NCT06760598
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoporosis, Osteoporotic Fractures
An Assessment of Treatment Adherence of Osteoporosis Patients From a Biopsychosocial Perspective
This observational study aims to learn about the psychosocial risk factors of osteoporosis (OP) patients. The main question it aims to answer is: Which biopsychosocial factors affect OP patients' fragility fracture risk regarding…
- Conditions
- Osteoporosis, Osteoporotic Fractures, Psychosocial Functioning, Medication Adherence
- Trial name
- NCT05943600
- Where
- Turkey (Türkiye)
- Volunteers
- 585 people
- Sponsor
- Istanbul University
Osteoporosis
Balance and Muscle Strength as Indicators of Fracture Risk in Postmenopausal Women
The study is designed as a cross-sectional clinical study. A total of 156 postmenopausal women who visited the Physical Therapy and Rehabilitation outpatient clinic at Beylikdüzü State Hospital and have had Dual X-ray…
- Trial name
- NCT06645600
- Testing
- Fracture risk
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Beylikduzu State Hospital
Osteoporosis, Fractures in the Elderly
Fractures in the Elderly Population of El Salvador at Hospital Zacamil: Exploring Knowledge, Causes, Risk Factors, and Outcomes
As the population's life expectancy increases, fractures among the elderly in El Salvador are also increasing. There is currently limited data specific to the incidence and cause of fractures in the elderly within developing…
- Trial name
- NCT00625599
- Testing
- Osteoporosis Prevention Information
- Where
- 2 sites in El Salvador
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Osteoporosis, Fracture Risk Assessment
New Tools for Assessing Fracture Risk
The goal of this study is to determine whether two new, non-X-ray techniques can discriminate between high-energy fractures of normal bone (trauma) and low-energy fractures (fragility) of osteoporotic bone.
- Trial name
- NCT02436356
- Testing
- Osteoprobe-Reference Point Indentation (RPI), Dual-energy X-ray absorptiometry (DXA) Scans, MRI
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Hypothyroidism, Osteoporosis
Awareness of Osteoporosis in Patients With Hypothyroidism
Osteoporosis is a condition that describes compromised skeletal microarchitecture in general, with clinical signs of decreased bone mineral density. Patients with hypothyroidism are at increased risk for developing osteoporosis.
- Conditions
- Hypothyroidism, Osteoporosis, Osteoporosis Risk
- Trial name
- NCT05760131
- Testing
- Patient Participation Form
- Volunteers
- 400 people
- Sponsor
- Uskudar State Hospital
Osteoporosis
Exercise as an Modulator of Immunological Risk Factors for Osteoporosis
This is the second phase of a study designed to determine the immunological effects of long-term exercise on risk factors for ischemic heart disease (phase 1) and osteoporosis (phase 2).
- Trial name
- NCT02765945
- Testing
- Supervised exercise program
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- East Tennessee State University
Healthcare; Risk Prediction; Diabetic Patients With Osteoporosis
A Model for Risk Prediction of Fracture in Diabetic Patients With Osteoporosis
The fracture risk of diabetic patients proves to be higher than those without diabetesdue to thehyperglycemia, usage of diabetes drugs, the changes in insulin levels and excretion, and this risk begins as early as…
- Trial name
- NCT04534166
- Testing
- Risk Prediction of Fracture in Diabetic Patients with Osteoporosis
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine