Clinical trials: Other Disease/Injury
Obesity, Metabolic Disease
Diet and Fat Mass After Traumatic Spinal Cord Injury
This is a randomized clinical controlled trial (RCT) to investigate the impact of a personalized nutritional intervention on functional and clinical outcomes the first year after traumatic spinal cord injury.
- Conditions
- Obesity, Metabolic Disease, Spinal Cord Injuries
- Trial name
- NCT04109586
- Testing
- Personalized nutritional therapy
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Ischemic Heart Disease, Nerve Injury
Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study
Evaluation of potential nerve damage after radial CAG/PCI.
- Conditions
- Ischemic Heart Disease, Nerve Injury, Carpal Tunnel Syndrome
- Trial name
- ACCESS-IV (NCT05365282)
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aarhus University Hospital Skejby
Renal Disease
Renal MR Feasibility in Renal Disease
To use Non-invasive MR Imaging of Renal Physiology and structure to assess patients with Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD).
- Trial name
- REMIND (NCT03578523)
- Testing
- 3 Tesla multiparametric MR, renal histopathology scoring, Blood and urine sampling
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Nottingham
Heart Diseases
Metoprolol to Reduce Perioperative Myocardial Injury
The purpose of this research study is to test if a commonly used, FDA-approved medication, called metoprolol, given at the conclusion of anesthesia following surgery, and during postoperative admission, reduces the possibility of…
- Trial name
- ORION (NCT03138603)
- Testing
- Metoprolol Tartrate
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Chicago
Coronavirus Infection, Multi-Organ Disorder
Capturing MultiORgan Effects of COVID-19
The C-MORE study is prospective observational holistic longitudinal study which will characterise the prevalence of multi-organ injury among COVID-19 survivors post hospital discharge and assess its effects on quality of life…
- Trial name
- C-MORE (NCT04510025)
- Testing
- Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Obsessive-Compulsive Disorder (OCD), Schizophrenia and Schizophrenia Spectrum Psychosis
Obsessive-Compulsive Disorder: Insight, Trauma, and Links to Schizophrenia Spectrum Disorders
This study aims to better understand Obsessive-Compulsive Disorder (OCD) by examining the types and patterns of OCD symptom presentation. The investigators seek to determine how these symptoms impact overall daily functioning.
- Trial name
- NCT07092826
- Testing
- Psychopathological assessment and non-invasive multisensory stimulation
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Matteo Tonna
Acute Kidney Failure With or Without:, MODS
Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT
1. To compare the differences of citrate pharmacokinetics in healthy individuals and critically ill patients as well as the influential factors. 2. To validate a pharmacokinetic model which has been established in a formal paper.
- Conditions
- Acute Kidney Failure With or Without:, MODS, Sepsis, Hepatic Insufficiency
- Trial name
- NCT00948558
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
COVID-19, Critical Illness
Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care
This is an observational study exploring the levels of mobility and rehabilitation in patients admitted to critical care with a confirmed diagnosis of COVID-19
- Conditions
- COVID-19, Critical Illness, Ards, ICU Acquired Weakness
- Trial name
- NCT04396197
- Testing
- Physiotherapy
- Where
- United Kingdom
- Volunteers
- 92 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Brain Injury, Chronic
Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
The purpose of this study is to determine if hyperbaric oxygen therapy (HBOT) improves the cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT00810615
- Testing
- Hyperbaric oxygen @ 2.4 ATA
- Volunteers
- 50 people
- Sponsor
- San Antonio Military Medical Center
Diastasis of Muscle, Other Site
Abdominal Diastasis Repair by Robotic Surgery
The objective of the study is to evaluate the feasibility of a robot-assisted minimally invasive surgical technique for the management of diastasis of the rectus abdominis.
- Trial name
- PROMA1 (NCT04176874)
- Testing
- Robotic-assisted diastasis of the rectus abdominis muscles repair
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Drug-Induced Liver Injury, Liver Failure
Comparative Study of Circulating microRNA Changes in Patients With Liver Injury and Healthy Subjects
The objectives are to: 1. validate a panel of tissue-specific miRNAs that are differentially expressed in the plasma of patients with and without liver injuries 2.
- Trial name
- NCT03000621
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Postcomatose Unawareness State, Minimally Conscious State
Eye Tracking Technology in the Diagnosis of Neurological Patients
Demonstrating that diagnostics of the state of consciousness and cognitive functions of patients with consciousness disorders performed using C-Eye X (based on eye-tracking technology) allows a more objective assessment of state…
- Conditions
- Postcomatose Unawareness State, Minimally Conscious State, Vegetative State, Disorder of Consciousness
- Trial name
- NCT05536921
- Where
- 5 sites in Poland
- Volunteers
- 90 people
- Sponsor
- AssisTech Sp. z o.o.
Heart Valve Disease
Effect of Propofol on Renal Injury in Patients Undergoing Valvular Heart Surgery
Ischemia/reperfusion (I/R)-induced acute kidney injury is a serious complication affecting patient outcome following cardiovascular surgeries.
- Trial name
- NCT01384643
- Testing
- Propofol
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Yonsei University
COVID-19, Coronavirus Disease 2019
Tigerase® Efficacy and Safety as Part of Complex Therapy in Patients With COVID-19
It is a multicenter, open-label, randomized, parallel-group study of the efficacy and safety of Tigerase® (GENERIUM JSC, Russia) with standard therapy versus standard therapy in patients with COVID-19.
- Trial name
- NCT04459325
- Testing
- Tigerase® and best available care, Best available care
- Where
- 6 sites in Russia
- Volunteers
- 100 people
- Sponsor
- AO GENERIUM
Chronic Subdural Hematomas, Cerebral Compression Due to Injury
Middle Meningeal Artery Embolization for Chronic Subdural Hematomas (STORMM)
Chronic Subdural Hematomas (cSHD) are common, and due to cerebral compression, often result in neurological impairment and reduced consciousness. Surgery is typically performed once neurological symptoms develop.
- Trial name
- STORMM (NCT06163547)
- Testing
- MMA embolization
- Where
- 2 sites in Switzerland
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Central Nervous System Disease, Cerebrovascular Accident
Brain Processing of Language Meanings
This research trial will study discourse processing-that is, how the brain processes the meaning of language. It will examine, for example, how words and sentences are interpreted in cases where more than one meaning is possible.
- Conditions
- Central Nervous System Disease, Cerebrovascular Accident, Craniocerebral Trauma, Head Injury
- Trial name
- NCT00005004
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cardiac Amyloidosis, Cardiac Disease
High Resolution Three-dimensional Maps of the Right Chambers in Patient Diagnosed With Cardiac Amyloidosis
Amyloid heart disease is an accumulation of fibrillar proteins in the extracellular sector of the heart. Identified on echocardiography as Ventricular hypertrophy.
- Trial name
- CARTO-AMYLO (NCT04956965)
- Testing
- Cardiac electro-mapping
- Where
- Martinique
- Volunteers
- 24 people
- Sponsor
- University Hospital Center of Martinique
Dissociative Disorder
Prevalence of Dissociative Identity Disorder in At-risk Outpatient Groups Reporting Childhood Trauma.
The investigators will study the prevalence of dissociative identity disorder (DID) in three populations at risk in cases of childhood psychotrauma : patients with a diagnosis of borderline personality, patients with a diagnosis…
- Trial name
- IDENTITY (NCT06330467)
- Testing
- psychometric assessment, semi-structured clinical interview
- Where
- 3 sites in France
- Volunteers
- 350 people
- Sponsor
- Centre Psychothérapique de Nancy
COVID-19, Pneumonia, Viral
SOLIRIS® (Eculizumab) Treatment of Participants With COVID-19
This protocol provides access to eculizumab treatment for participants with severe COVID-19.
- Conditions
- COVID-19, Pneumonia, Viral, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
- Trial name
- NCT04355494
- Testing
- eculizumab
- Where
- 12 sites in United States, France
- Sponsor
- Alexion Pharmaceuticals, Inc.
Traumatic Brain Injury, Brain Injury, Chronic
Evaluation of an Intervention Model for Family Crisis and Support
To learn more about how a family treatment program helps people after brain injury. Specifically, do families feel better and function better after going through the program, and do patients feel better and function better after…
- Trial name
- NCT00205530
- Testing
- Brain Injury Family Intervention (BIFI)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Virginia Commonwealth University
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