Clinical trials: Other Disease/Injury
Stroke, Chronic Brain Injury
Automated Stereognosis to Treat Loss of Tactile Function After Brain Injury
Researchers aim to determine whether the ReTrieve system for tactile training can improve tactile function (sense of touch) in the hand after brain injury when used at home for 6 weeks.
- Conditions
- Stroke, Chronic Brain Injury, Peripheral Neuropathy
- Trial name
- ReTrieve (NCT05740553)
- Testing
- ReTrieve Automated Stereognosis System
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas at Dallas
Coronary Artery Disease,
Pathophysiology and Prevention of Perioperative Myocardial Injury: A Prospective Randomized Controlled Trial
Working hypothesis and aims: 1) To explore the pathophysiology of postoperative troponin elevations and 2) whether ranolazine, a new anti-ischemic drug that has no effect on blood pressure or heart rate, prevents postoperative…
- Trial name
- NCT01810796
- Testing
- Ranolazine
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Brain Injury, Craniocerebral Trauma
Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head Injury
OBJECTIVES: I. Determine the randomness of adrenocorticotropic hormone (ACTH) and cortisol secretion using approximate entropy in patients who have sustained a head injury. II.
- Trial name
- NCT00006270
- Testing
- cosyntropin, metyrapone
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- National Center for Research Resources (NCRR)
COVID, AKI
Epidemiology of Acute Kidney Injury in COVID19 Disease in United Kingdom
Severe Acute respiratory syndrome coronovirus (SARS-CoV-2) was first described in Wuhan in December 2019. It quickly spread to rest of the world and was declared pandemic by World health organisation.
- Trial name
- NCT04407156
- Testing
- acute kidney injury
- Where
- United Kingdom
- Volunteers
- 724 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Chronic Lung Disease of Prematurity, Respiratory Distress Syndrome in Premature Infant
PAL to Improve Oral Feeding for Infants With Chronic Lung Disease
The purpose of this study is to investigate the effects of the Pacifier Activated Lullaby (PAL) intervention on the transition to oral feeding for preterm infants with chronic lung disease and respiratory distress syndrome that…
- Conditions
- Chronic Lung Disease of Prematurity, Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia, Preterm Birth
- Trial name
- NCT05446389
- Testing
- Pacifier Activated Lullaby ®
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Missouri-Columbia
Traumatic Brain Injury, Cerebral Palsy
Real World Outcomes of Intranasal MuSE Exosomes and Stem Cells in Neurological Regenerative Therapy
This prospective observational study collects real world data on participants receiving regenerative therapies administered internationally and delivered intranasally via the Kurve Therapeutics ViaNase device.
- Conditions
- Traumatic Brain Injury, Cerebral Palsy, Hypoxic Ischemic Encephalopathy, Neurologic Disorders
- Trial name
- MuSE-INSIGHT (NCT07521384)
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Healing Hope International
Chronic Kidney Disease
RenalGuard System and Contrast Media
The purpose of the present study is to assess the role of the RenalGuard System as compared to the optimal strategy (sodium bicarbonate infusion plus N-acetylcysteine (NAC)) in high and very-high risk patients to prevent…
- Trial name
- REMEDIALII (NCT01098032)
- Testing
- RenalGuard system, Systemic alone therapy
- Where
- 4 sites in Italy
- Volunteers
- 294 people
- Sponsor
- Clinica Mediterranea
Acute Kidney Injury, Sepsis
MULTIMODAL APPROACH IN THE DIAGNOSIS OF SEPTIC AKI
In recent studies, it has been reported that the renal resistance index is effective in detecting sepsis-related acute renal failure (SA-AKI) in the early period.
- Conditions
- Acute Kidney Injury, Sepsis, Critical Illness, Renal Resistive Index
- Trial name
- SEPTIC AKI (NCT07472452)
- Testing
- Renal Resistive Index (RRI) Doppler Ultrasound, Urinary TIMP-2 and IGFBP-7 biomarkers
- Volunteers
- 130 people
- Sponsor
- Ankara Etlik City Hospital
Myocardium; Injury, Coronary Artery Disease
Association of Serum Eotaxin Levels and Markers of Myocardiac Injury in Hemodialysis Patients
Background: Cardiovascular disease (CVD) is one of the leading causes of morbidity and mortality among dialysis patients. Eotaxin-1(also known as Eotaxin and CCL11), an eosinophil-specific chemoattractant that plays a role in a…
- Trial name
- NCT06211244
- Where
- Taiwan
- Volunteers
- 291 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Antiplatelet Drug-related Gastrointestinal Injury
Long-term MOno-Antiplatelet Drug Strategy After PerCutanEous CoronAry InterveNtion
The OCEAN (long-term mOn-antiplatelet drug strategy after perCutanEous coronANy intervention) study is the largest prospective multicenter data base to investigate the long-term incidence and prognosis of the use of agents for…
- Trial name
- RESCIND-OCEAN (NCT03725800)
- Where
- 8 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Critically Ill, Acute Kidney Injury
Comparison of Biphozyl® and Phoxilium® as a Replacement Fluid During CVVH for AKI in Adults and Their Effects on pH-, Bicarbonate-levels and Respiratory Situation
The primary objectives of the BiPhox-Trial are to demonstrate, that the use of Biphozyl® as a replacement fluid in adult critically ill acute kidney injury (AKI) patients, results in a lower rate of pH excursions and of…
- Conditions
- Critically Ill, Acute Kidney Injury, Renal Replacement Therapy, Continuous Renal Replacement Therapy
- Trial name
- NCT04071171
- Testing
- CVVH with Phoxilium® in the first 48h after randomization, CVVH with Biphozyl® in the first 48h after randomization, CVVH with Phoxilium® in the second 48h after randomization (after previous 48h with Biphozyl®)
- Where
- Austria
- Volunteers
- 88 people
- Sponsor
- Medical University Innsbruck
Liver Diseases
DILIN - Prospective Study
The purpose of this study is to identify individuals who have suffered a liver injury arising as an idiosyncratic reaction to a prescription drug or a complementary and alternative medicine.
- Trial name
- NCT00345930
- Where
- 6 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Duke University
BPD - Bronchopulmonary Dysplasia, VLBW - Very Low Birth Weight Infant
Duodenal Feeds in Very Low Birth Weight Infants
Premature infants have high rates of bronchopulmonary dysplasia (BPD) due to prematurity of the participants' lungs and the need for prolonged respiratory support.
- Conditions
- BPD - Bronchopulmonary Dysplasia, VLBW - Very Low Birth Weight Infant, Feeding Disorder Neonatal, Feeding; Difficult, Newborn
- Trial name
- NCT04246333
- Testing
- Mode of Delivery of Feeds
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
MTBI - Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury
Rapid Diagnosis and Prognosis Recognition of Imaging and Biomarkers in Mild to Moderate Traumatic Brain Injury
The investigators will carry out multi-center and large sample research based on the Chinese population, screen the optimal diagnostic and prognosis recognition biomarkers and analyze the diagnostic critical cutoff values in…
- Trial name
- NCT05108909
- Testing
- MRI, CT, and serum biomarkers
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cardiovascular Disease, Ischemia-reperfusion Injury
Effect of Ischemic Postconditioning on Targeting of Annexin A5 After Forearm Exercise
To adjust our forearm model for ischemia reperfusion injury, in order to used it for assessment of ischemia reperfusion damage in elderly and patients.
- Conditions
- Cardiovascular Disease, Ischemia-reperfusion Injury, Postconditioning
- Trial name
- NCT00441714
- Testing
- repetitive short ischemia and reperfusion of non dominant fore arm after 10 minute ischemic exercise
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Acute Kidney Injury, Chronic Renal Disease
Prediction of Chronic Renal Disease After Acute Kidney Injury in the Intensive Care Unit
The study aims to develop and validate a prediction score of chronic renal disease occurrence within 3 years after ICU discharge in patients who suffered an acute kidney failure during ICU stay and recovered normal renal function…
- Trial name
- PREDICT (NCT03282409)
- Where
- France
- Volunteers
- 425 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Failure, Acute Renal Failure
Premarket Clinical Safety Assessment of the ELISIO™-HX
The primary safety objective of this study is to evaluate the safety of the use of the high-permeability hemodialyzer series ELISIO™-HX, by showing that the pre-dialysis albumin levels are not affected using the investigational…
- Conditions
- Renal Failure, Acute Renal Failure, Chronic Renal Failure, Chronic Kidney Diseases
- Trial name
- NCT07058909
- Testing
- ELISIO™-HX Dialyzer
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Nipro Medical Corporation
Occupational Diseases, Work-related Injury
Effect of Passive and Active Rest Break in Musculoskeletal Complains
Work-related musculoskeletal disorders are highly disabling. Therefore, finding preventive solutions is fundamental, in order to reduce the damages to workers and society.
- Trial name
- NCT03559153
- Testing
- Shiatsu massage, Physical Exercise
- Where
- Brazil
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Universidade Cidade de Sao Paulo
Degenerative Sacroiliitis, Sacroiliac Joint Disruption
Sacroiliac Joint Fusion With iFuse Implant System (SIFI)
The purpose of this study is to evaluate the use of the iFuse Implant System to treat degenerative sacroiliitis (arthritis of the SI joint) and sacroiliac disruption (abnormal separation or tearing of the sacroiliac joint).
- Trial name
- SIFI (NCT01640353)
- Where
- 26 sites in United States
- Volunteers
- 194 people
- Sponsor
- SI-BONE, Inc.
Acute Kidney Injury, Chronic Kidney Disease
Nephrologist Follow-up Versus Usual Care After an Acute Kidney Injury Hospitalization
The primary objective is to evaluate the impact of an AKI Follow-up Clinic on major adverse kidney events (MAKE) in comparison to hospitalized patients surviving an episode of AKI who are not exposed to the AKI Follow-up Clinic…
- Trial name
- FUSION (NCT02483039)
- Testing
- AKI Follow-up Clinic
- Where
- 4 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Unity Health Toronto
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