Clinical trials: Other Disease
Ulcerative Colitis
Long-Term Safety and Tolerability of Mesalamine Pellets in Participants With Ulcerative Colitis in Remission
To evaluate the long-term safety and tolerability of encapsulated mesalamine Granules (eMG) (formerly referred to as Mesalamine Pellets [MP]) in participants with ulcerative colitis currently in remission.
- Trial name
- NCT00326209
- Testing
- Encapsulated Mesalamine Granules (eMG)
- Where
- 61 sites in United States
- Volunteers
- 393 people
- Sponsor
- Bausch Health Americas, Inc.
Care Givers, Burden, Caregiver
The Effect of a Mindfulness-Based Self-Compassion Program on Care Burden, Life Satisfaction, and Coping Levels of Caregivers of Individuals With Schizophrenia
This study aims to examine the effect of the Mindfulness-Based Self-Compassion Program on caregiver burden, life satisfaction, and coping with stress levels among caregivers of individuals diagnosed with schizophrenia.
- Conditions
- Care Givers, Burden, Caregiver, Stress, Satisfaction With Life
- Trial name
- NCT06941909
- Testing
- Mindfulness-Based Self-Compassion
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Neslihan Lok
Health Care Associated Infection, Hand Hygiene
Reducing Intraoperative Infection Transmission in the Pediatric Operating Room
Patients becoming infected during hospitalization occurs frequently and causes harm. It is important for healthcare facilities to take action to prevent these infections and their spread between patients.
- Trial name
- NCT03992209
- Testing
- Standard care, Protocolized care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alzheimer's Disease
An Open-label Extension to Evaluate the Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease
The goal of this research study is to evaluate, in the open-label extension phase, the safety and efficacy of the rivastigmine transdermal patch in patients with probable Alzheimer's Disease
- Trial name
- NCT00219232
- Testing
- Rivastigmine Transdermal Patch
- Volunteers
- 868 people
- Sponsor
- Novartis
Low Vision, Retinitis Pigmentosa
Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision
Purpose: To validate a newly developed battery of performance-based tests of visual function to be presented using virtual reality.
- Conditions
- Low Vision, Retinitis Pigmentosa, Stargardt Disease 1, Stargardt Disease 3
- Trial name
- NCT04281732
- Testing
- Virtual Reality Headset based tests
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Queen's University, Belfast
Colles' Fracture, Colles' Fracture of Unspecified Radius, Sequela
PRediction of Outcome With ED Intervention for Colles Type Wrist Fractures [PREDICT]
The Colles fracture, a fracture of the wrist, is frequently associated with deformity of the broken part of the bone, particularly in older or frail patients.
- Trial name
- PREDICT (NCT03859999)
- Testing
- Analysis of primary radiograph and available demographics
- Where
- United Kingdom
- Volunteers
- 279 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Post-COVID-19 Syndrome, Post-COVID Syndrome
Immunoadsorption Study Mainz in Adults With Post-COVID Syndrome
The aim of this study is to evaluate the efficiency and safety of immunoadsorption for the treatment of post-COVID syndrome (PCS).
- Conditions
- Post-COVID-19 Syndrome, Post-COVID Syndrome, Post COVID-19 Condition
- Trial name
- IAMPOCO (NCT05841498)
- Testing
- Immunoadsorption
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Medical Center Mainz
Hepatitis B
A Study of GC1102(Recombinant Hepatitis B Immunoglobulin) in Chronic Hepatitis B Patients
The purpose of this study is to evaluate the efficacy and safety of GC1102 in combination of Nucleo(t)ide analogues (NAs) in patients with chronic hepatitis B
- Trial name
- NCT03801798
- Testing
- GC1102
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Green Cross Corporation
Liver Cirrhosis, Hepatocellular Carcinoma
Relevance of Sarcopenia in Advanced Liver Disease
Patients with established liver cirrhosis, or end-stage liver disease (ESLD), are at high risk of developing liver cancer (hepatic carcinoma; HCC), portal hypertension, and sarcopenia, all which lead to significant morbidity and…
- Conditions
- Liver Cirrhosis, Hepatocellular Carcinoma, Sarcopenia, Portal Hypertension
- Trial name
- ACCESS-ESLD (NCT05502198)
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
Pelizaeus-Merzbacher Disease, PMD
Long-Term Follow-Up Study of Human Stem Cells Transplanted in Subjects With Connatal Pelizaeus-Merzbacher Disease (PMD)
The purpose of this study is to determine the long term safety and preliminary effect of HuCNS-SC cells transplanted in subjects with Connatal Pelizaeus-Merzbacher Disease (PMD).
- Trial name
- NCT01391637
- Testing
- HuCNS-SC transplant in the lead-in phase
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- StemCells, Inc.
Idiopathic Parkinson's Disease
Safinamide as Add-On Therapy in Patients With Early Idiopathic Parkinson's Disease Treated With a Stable Dose of a Single Dopamine Agonist
To evaluate the safety and efficacy of two dose ranges of safinamide (High Dose: 150 to 200 mg/day and Low Dose: 50 to 100 mg/day) orally, as compared to Placebo, as add-on therapy in patients with early idiopathic Parkinson's…
- Trial name
- NCT00643045
- Testing
- Safinamide
- Volunteers
- 269 people
- Sponsor
- Newron Pharmaceuticals SPA
Abdomen, Acute, Other Acute Pain
Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department
The purpose of this study is to compare the safety and effectiveness of intravenous low dose ketamine (LDK) to the industry standard of morphine (MOR) in regards to controlling acute pain in the emergency department.
- Conditions
- Abdomen, Acute, Other Acute Pain, Flank Pain, Back Pain
- Trial name
- NCT01538745
- Testing
- Ketamine, Morphine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Brooke Army Medical Center
Thymoma, Stomach Neoplasms
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
Background: Malignant mesothelioma is a malignancy arising from the mesothelial cells of the pleura, peritoneum, pericardium, or tunica vaginalis. Mesothelioma accounts for 0.10% of deaths annually in the United States.
- Conditions
- Thymoma, Stomach Neoplasms, Pancreatic Neoplasms, Mesothelioma
- Trial name
- NCT01950572
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Cancer Institute (NCI)
Parkinson Disease
Comparison of Health Care Delivery Methods in Parkinson's Disease
The goal of this observational study is to compare the ability to perform telemedicine visits at home, at a regional clinic close to home, and in-person in People with Parkinson's disease.
- Trial name
- NCT05725772
- Testing
- Location of Visit
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Posterior Column Ataxia With Retinitis Pigmentosa
Antisense Oligonucleotide Treatment for PCARP Disease Due to Mutation in FLVCR1
The goal of this clinical trial is to evaluate a specific antisense oligonucleotide medication in one patient with posterior column ataxia with retinitis pigmentosa.
- Trial name
- NCT06565572
- Testing
- nL-FLVC-001
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Colorado, Denver
Sexual Risk Behavior, Drug Use
eHealth Evidence-based Intervention (EBI) for Latino Youth in Primary Care
The purpose of this study is to test the relative effectiveness of a Hispanic-specific eHealth intervention, "e-Health Familias Unidas," in preventing and reducing drug use, sexual risk behaviors, and STIs among Hispanic youth in…
- Conditions
- Sexual Risk Behavior, Drug Use, Family Functioning
- Trial name
- NCT03009539
- Testing
- eHealth Familias Unidas Primary Care
- Where
- 12 sites in United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- University of Miami
Obesity, Hypertrophic Cardiomyopathy
Association of Obesity and Cardiovascular Outcomes in Hypertrophic Cardiomyopathy
In this study, the investigators evaluated the association between various measures of adiposity [BMI and waist circumference (WC)] and clinical outcomes in Asian patients with hypertrophic cardiomyopathy, using a nationwide…
- Conditions
- Obesity, Hypertrophic Cardiomyopathy, Cardiovascular Morbidity
- Trial name
- Paradox (NCT05645939)
- Testing
- Diasgnosis of hypertrophic cardiomyopathy
- Where
- South Korea
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Epithelial Ovarian Cancer, Relapse
Tri Association in Patient With Advanced Epithelial Ovarian Cancer in Relapse
Assessing the safety and efficacy of the bevacizumab, Olaparib and Durvalumab (MEDI 4736) combination in patient with high grade serous or high grade endometrioid or other high grade epithelial non mucinous ovarian tumor, with at…
- Trial name
- BOLD (NCT04015739)
- Testing
- Bevacizumab, Olaparib and Durvalumab (MEDI 4736) combination
- Where
- 9 sites in France
- Volunteers
- 74 people
- Sponsor
- ARCAGY/ GINECO GROUP
Schizophrenia
A Repeat Dose Positron Emission Tomography Study With GSK1144814
This study described in the present protocol consists of two parts. Part A is a multiple ascending dose study to evaluate the safety, tolerability and pharmacokinetics of ascending doses of GSK1144814.
- Trial name
- NK1 NK3 PET (NCT01209039)
- Testing
- GSK1144814
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Coronary Artery Disease
BIOFLOW-INDIA Safety and Clinical PerFormance of the Drug Eluting ORSIRO Stent in Single de Novo Coronary Artery Lesions
The objective of this clinical investigation is to assess the safety and clinical performance of the Orsiro Limus Eluting Stent System in Indian subjects with single de-novo coronary artery lesions.
- Trial name
- NCT01426139
- Testing
- Percutaneous Coronary Intervention Biotronik Orsiro DES
- Where
- 4 sites in India
- Volunteers
- 120 people
- Sponsor
- Biotronik AG
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