Clinical trials: Other Disease
Alzheimer Disease
Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531
To assess the safety and tolerability of ascending multiple oral doses of SAM-531, an investigational drug, in healthy Japanese young male and elderly subjects.To provide the pharmacokinetics (PK) and pharmacodynamics (PD)…
- Trial name
- NCT00479349
- Testing
- SAM-531
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Inflammatory Bowel Disease (IBD), Hepatitis B Virus
Impact of Hepatitis B Virus on Inflammatory Bowel Disease
The goal of this observational retrospective study is to assess the impact of hepatitis B virus (HBV) infection on the clinical course and outcomes of inflammatory bowel disease (IBD) in Egyptian patients.
- Trial name
- NCT06881238
- Testing
- History of IBD course and outcome in HBV patients
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Tanta University
Crohn Disease, Pediatric Inflammatory Bowel Diseases
Microplastic Analysis in Pediatric Inflammatory Bowel Disease
The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD.
- Conditions
- Crohn Disease, Pediatric Inflammatory Bowel Diseases, Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- MAP-IBD (NCT07141238)
- Testing
- Environmental microplastic exposure
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Cystic Fibrosis, Chronic Obstructive Pulmonary Disease (COPD)
Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Women with chronic lung disease characterised by chronic cough report urinary incontinence. Recently there have been reports of increased urinary incontinence in girls and women with cystic fibrosis.
- Trial name
- NCT00164138
- Testing
- Pelvic floor training group
- Where
- 2 sites in Australia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Multivessel Coronary Artery Disease
Clinical Implication of 3-vessel Fractional Flow Reserve (FFR)
This study will evaluate the influence of total atherosclerotic burden assessed by 3-vessel fractional flow reserve (FFR) on the clinical outcomes of the patients with multi-vessel disease.
- Trial name
- NCT01621438
- Where
- 20 sites in China, Japan and 3 more
- Volunteers
- 1,136 people
- Sponsor
- Seoul National University Hospital
Chronic Obstructive Pulmonary Disease
BACE Trial Substudy 2 - FarmEc Substudy
A second sub-analysis of the BACE trial will include a detailed cost-effectiveness study.
- Trial name
- FarmEc (NCT02205255)
- Testing
- Azithromycin
- Where
- 20 sites in Belgium
- Volunteers
- 350 people
- Sponsor
- Wim Janssens
Migraine
Biomarker and Genetic Predictors of Erenumab Treatment Response
To explore the relationship between clinical response to erenumab and genetic biomarkers
- Trial name
- INTERROGATE (NCT04265755)
- Testing
- Erenumab
- Where
- 2 sites in Denmark, Iceland
- Volunteers
- 1,406 people
- Sponsor
- Amgen
Coronary Artery Disease, Inflammatory Response
Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels
To study the anti-inflammatory effects of marine omega-3 fatty acids, also known as n-3 polyunsaturated fatty acids (PUFA), we propose a randomized, double-blinded, prospective, single-center trial to examine the effect of…
- Conditions
- Coronary Artery Disease, Inflammatory Response, Atherosclerosis
- Trial name
- Omega-3 (NCT00578578)
- Testing
- eicosapentaenoic acid (EPA),
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- The Cleveland Clinic
Eye Disease
Analysis of Human Tear Proteins in Children
The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film, and any unique aspects of tears in children.
- Trial name
- NCT00473278
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pancreatitis, Pancreatic Disease
Activation of Biobank Registry for Bilio-pancreatic Diseases
The purpose of establishing the biobank is to create a collection of biological material and clinical data, with a prospective and retrospective mold, in order to investigate the role of genetic predisposition in multifactorial…
- Conditions
- Pancreatitis, Pancreatic Disease, Non-Neoplastic Pancreatic Disorder, Pancreatic Adenocarcinoma
- Trial name
- BIO-PANCREAS (NCT06552078)
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Sickle Cell Disease
MACS Study - Microparticles and Coagulation in Sickle Cell Disease
Sickle cell disease (SCD) is an inherited disorder of the red blood cell. It is now the commonest genetic disorder in the UK and of childhood stroke, with up to 40% of children having a stroke (clinical or picked up on a scan) by…
- Trial name
- MACS (NCT01242878)
- Where
- 3 sites in United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University College, London
Secondary Hyperparathyroidism
Observational Program of Zemplar in Patients With End Stage Chronic Kidney Disease and Parathyroid Disorder on Hemodialysis in the Russian Federation
Eighty-six eligible participants with secondary hyperparathyroidism will be enrolled at thirteen sites in Russia. Planned therapy will be six months.
- Trial name
- NCT01401478
- Where
- 13 sites in Russia
- Volunteers
- 86 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Pulmonary Hypertension
Study of Inhaled Iloprost for the Treatment of Pulmonary Hypertension After Repair of Congenital Heart Disease
The objective of this study was to assess the efficacy and appropriate dose of iloprost for inhalation in the treatment of postoperative pulmonary hypertension in children with congenital heart defects.
- Trial name
- NCT01320878
- Testing
- iloprost nebuliser solution, distilled water
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Torsion Testis, Scrotum Disease
Is ICG Imaging Safe and Accurate to Predict Testicular Torsion?
Testicular torsion is a time critical condition for children and young people (CYP). It is difficult to diagnose without an operation. Missing it means the child will lose a testicle.
- Trial name
- NCT07545278
- Testing
- Indocyanine green fluorescence injection and near infra red spectroscopy image capture
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sheffield Children's NHS Foundation Trust
Aphthous Stomatitis, Recurrent, Aphthous Stomatitis
Effect of Alum Stone Containing Mucosal Adhesive Patches on Healing of Recurrent Aphthous Stomatitis
The evaluation of recurrent aphthous stomatitis (RAS) was performed by an oral medicine specialist, who relied on the clinical manifestations of the condition.
- Conditions
- Aphthous Stomatitis, Recurrent, Aphthous Stomatitis, Aphthous Ulcer
- Trial name
- NCT06960278
- Testing
- Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5., Control, ALUMSTONE
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Of Anbar
Cardiovascular Disease
Canola Oil Multicentre Intervention Trial (COMIT)
The objectives of this study are to examine how the consumption of treatment oils (including canola oil, DHA enriched canola-oil, high oleic acid canola oil, flax oil, and safflower oil) influence endothelial function…
- Trial name
- COMIT (NCT01233778)
- Testing
- Canola Oil, High Oleic Acid + DHA Canola Oil, High Oleic Acid Canola Oil
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Penn State University
Parkinson Disease, Fall
Steps Against the Burden of Parkinson's Disease - RCT Kiel
Parkinson's disease (PD) affects over 10 million worldwide, causing unstable gait and falls in 70% of patients despite medication. This leads to confidence loss, isolation, fractures, and hospitalizations.
- Trial name
- StepuP (NCT07058285)
- Testing
- Speed-dependent treadmill training (SDTT), SDTT+ anteroposterior perturbations
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Kiel
Minimal Residual Disease, Leukemia, Lymphoblastic, Acute
Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia
This study will test the ability of clofarabine + cytarabine to eliminate minimal residual disease (MRD) in acute myelogenous leukemia (AML) and acute lymphoblastic leukemia (ALL) patients whose bone marrows exhibit complete…
- Conditions
- Minimal Residual Disease, Leukemia, Lymphoblastic, Acute, Leukemia, Myelogenous, Acute
- Trial name
- NCT01158885
- Testing
- Clofarabine, Cytarabine intravenous, Methotrexate
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Therapeutic Advances in Childhood Leukemia Consortium
Parkinson's Disease, Chronic Appendicitis
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients.
- Conditions
- Parkinson's Disease, Chronic Appendicitis, Acupuncture
- Trial name
- NCT06304285
- Testing
- Acupuncture treatment
- Where
- China
- Volunteers
- 84 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Dry Eyes, Sjogren's Disease With Dry Eyes
Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood
To investigate if fresh finger prick autologous blood (FAB) instead of serum from venesection, is a safe and effective treatment for dry eyes and corneal ulcers/ epithelial defects.
- Conditions
- Dry Eyes, Sjogren's Disease With Dry Eyes, Persistent Corneal Epithelial Defects, Chronic Corneal Ulcers
- Trial name
- FAB (NCT02153515)
- Testing
- Your own ( autologous) finger prick of blood produced with a diabetic lancet
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Bedford Hospital NHS Trust
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