Clinical trials: Otitis
Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo
Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy
This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of…
- Conditions
- Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo, Meniere Disease, Vestibular Neuritis
- Trial name
- VR-PVD-RCT (NCT05424302)
- Testing
- Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation, Standard Vestibular Rehabilitation with Adjunct Auditory Intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Otitis Media
Vaccination for Middle Ear Infection
Acute otitis media (OM) and OM with effusion are common childhood diseases. Otitis media is a condition marked by inflammation of the middle ear.
- Trial name
- NCT00001605
- Testing
- Nontypeable Haemophilus influenzae
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Otitis Media, Middle Ear Effusion
Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11
Middle-ear disease (infection and fluid) is the most common illness in young children after the common cold. Because hearing loss accompanies middle-ear disease, and because early life is a period of rapid development, concern…
- Trial name
- NCT00365092
- Testing
- Insertion of tympanostomy tubes
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Otitis Media
Nasal Xylitol in the Prevention of Otitis Media
Acute otitis media (AOM) is one of the most prevalent and costly illnesses in children throughout the world. AOM can lead to chronic otitis media with effusion (OME) resulting in conductive hearing loss that can cause speech…
- Trial name
- NCT02592382
- Testing
- Xylitol spray
- Where
- 2 sites in Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Healthy
Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3c
This study will determine if gas can pass between the environment and the middle ear by way of the eardrum. This route of gas exchange was observed in animals but has not been studied in humans.
- Trial name
- NCT00422851
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hearing Loss, Otitis Media With Effusion
Sound Ear Check (SEC) in Hearing Diagnostics in Young Children
Study Sound Ear Check (SEC) hearing test among 3-10 years old otherwise healthy children referred to tympanostomy tube placement.
- Conditions
- Hearing Loss, Otitis Media With Effusion, Tympanostomy
- Trial name
- NCT05535634
- Testing
- Sound Ear Check
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vesa Lahdes
Infections, Streptococcal
A Study to Compare the Immunogenicity of GSK Biologicals' 10Pn-PD-DiT 4-dose Presentation to the Licensed 1-dose Synflorix™ (10Pn-PD-DiT) Vaccine When Co-administered With DTPw-combination Vaccine in Healthy Infants
The primary aim of the study is to demonstrate that an investigational 4-dose presentation of the 10Pn-PD-DiT vaccine with preservative is non-inferior to the licensed presentation of Synflorix (preservative-free) in terms of…
- Trial name
- NCT02447432
- Testing
- Pneumococcal vaccine GSK1024850A (10Pn-PD-DiT) vaccine (4-dose presentation), Pneumococcal vaccine GSK1024850A (10Pn-PD-DiT) vaccine (1-dose presentation), DTPw-HBV/Hib
- Where
- Bangladesh
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pneumonia, Meningitis
Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children
The study aims to evaluate the safety and immunogenicity of the 10-valent and 13-valent pneumococcal conjugate vaccines when administered in an accelerated schedule in Papua New Guinean children, who experience early dense upper…
- Conditions
- Pneumonia, Meningitis, Bacteraemia, Sepsis
- Trial name
- PCV1103 (NCT01619462)
- Testing
- Prevenar 13 and Synflorix
- Where
- Papua New Guinea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Papua New Guinea Institute of Medical Research
Upper Respiratory Tract Infections, Rhinopharyngitis
Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Upper Respiratory Tract Infections, Rhinopharyngitis, Sore Throat, Sinusitis
- Trial name
- NCT01315418
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- France
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Otitis Media With Effusion
Wideband Tympanometry in Otitis Media With Effusion
The investigators asked the question if they can better estimate the middle ear status in OME that help them to decide between early intervention or longer follow up.
- Trial name
- NCT04395261
- Testing
- Wideband Tympanometry
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Otitis Media
Echinacea Purpurea and Osteopathy in Children With Recurrent Otitis Media
This study was designed to evaluate the efficacy of the herb Echinacea purpurea and of cranial osteopathic manipulative treatment to prevent otitis media (middle ear infections) in young children.
- Trial name
- NCT00689468
- Testing
- Cranial osteopathic manipulative treatment., Echinacea purpurea
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Acute Otitis Media, Pneumonia
Vaccination Impact Against Pneumococcal Disease on Acute Otitis Media Morbidity in Colombian Children < 5 Years of Age
The purpose of this study is to provide data on trends of morbidity due to Acute Otitis Media (AOM) (primary analysis) and morbidity and mortality due to pneumonia, and AOM related health care resources before and after the…
- Trial name
- NCT02567747
- Testing
- Data collection
- Where
- Colombia
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Otitis Media, Allergic Rhinitis
A Trial of Point of Care Information in Ambulatory Pediatrics
Does presentation of clinical evidence for decision making at point-of-care improve prescribing patterns in ambulatory pediatrics?
- Conditions
- Acute Otitis Media, Allergic Rhinitis, Sinusitis, Constipation
- Trial name
- NCT00368823
- Testing
- Electronic point-of-care delivery system
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pulmonary Diseases, Tonsillar Hypertrophy
The Influence of Feeding Position on Pulmonary Morbidity in Young Children
Supine feeding position is associated with serous otitis media. The hypothesis is that supine feeding is associated with recurrent otitis media, tonsillar and adenoid hypertrophy and recurrent pneumonia secondary to recurrent…
- Conditions
- Pulmonary Diseases, Tonsillar Hypertrophy, Otitis Media, Dental Caries
- Trial name
- NCT00248391
- Testing
- upright feeding
- Where
- Israel
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Otitis Media With Effusion
Otitis Media With Effusion and Type 2 Inflammation Diseases
Otitis media with effusion (OME) is thought to be associated with comorbidities such as allergic rhinitis, gastroesophageal reflux disease, asthma, and more. Many of these comorbidities can be caused by type 2 inflammation (T2I).
- Trial name
- NCT06403319
- Volunteers
- 100,622 people, healthy volunteers welcome
- Sponsor
- Hearing and Language Healthcare Center, China Medical University Hsinchu Hospital, Taiwan
Otitis Media Acute
Otitis Treatment With OtoSight™ - Modification of Antibiotic Treatment Intervention in Children
A pragmatic, mixed-method trial is to show the ability of OtoSight to change management of the pediatric patient presenting with ear pain in a way that improves patient outcomes and reduces costs.
- Trial name
- OTO-MATIC (NCT06285812)
- Testing
- OtoSight Middle Ear Scope
- Where
- 7 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- PhotoniCare, Inc.
Antibiotic Associated Diarrhea, Acute Otitis Media
Effects of Saccharomyces Boulardii CNCM I-745 on Antibiotic-Associated Perturbation in Children Treated for Acute Respiratory Infections (RESTORE Study)
This study aims to evaluate the effect of co-administering the probiotic Saccharomyces boulardii CNCM I-745 with amoxicillin-clavulanic acid on the intestinal and nasopharyngeal microbiota in children diagnosed with acute otitis…
- Conditions
- Antibiotic Associated Diarrhea, Acute Otitis Media, ACUTE SINUSITIS
- Trial name
- RESTORE (NCT07015736)
- Testing
- Amoxicillin-Clavulanic acid 600mg - 42.9 mg/ 5 mL oral suspension, Saccharomyces boulardii CNCM I-745
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Acute Upper Respiratory Infection, Acute Lower Respiratory Tract Infection
Impact of Introduction of PHiD-CV for Nunavik Children, Quebec, Canada
The objective of this study is to document the residual burden of acute upper respiratory infections (AURIs), acute lower respiratory infections (ALRIs), otitis media (OMs) and auditory functional and anatomical abnormalities in…
- Conditions
- Acute Upper Respiratory Infection, Acute Lower Respiratory Tract Infection, Otitis Media (OM), Invasive Pneumococcal Disease, Protection Against
- Trial name
- Nunavik2 (NCT01694329)
- Where
- Canada
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Urinary Tract Infection, Diabetes Mellitus
Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station
The study objective is to satisfy the testing requirements for the Qualcomm Tricorder XPRIZE Competition. This requires an oversight model using the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station to…
- Conditions
- Urinary Tract Infection, Diabetes Mellitus, Atrial Fibrillation, OSA
- Trial name
- NCT02856633
- Testing
- Vitaliti
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cloud DX Inc.
Acute Otitis Media, Otitis Media
Parent-led Assessment and Recognition of AOM Using Digital Ear Imaging
Acute otitis media (AOM) is the most common bacterial infection in young children and a major contributor to healthcare utilization and costs.
- Trial name
- PARENT-EAR (NCT07640568)
- Testing
- Assigning of a digital otoscope to the families in the intervention group
- Where
- 2 sites in Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital