Clinical trials: Otitis Media With Effusion (OME)
Otitis Media With Effusion, Hearing Loss
Autoinflation: Alternative in the Treatment of Otitis Media With Effusion
Otitis media with effusion (OME) is a common finding affecting children and the main cause of acquired hearing loss in the pediatric age.
- Trial name
- OME (NCT05324696)
- Testing
- autoinflation device
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Otitis Media With Effusion, Probiotics
Effect of Probiotics on Nasopharyngeal Microbiome of Children With Otitis Media With Effusion
The aim of this study is to investigate whether the microbiota in the upper respiratory tract (nasopharynx, adenoids and middle ear fluid) of otitis media with effusion (OME) patients is changed after 4 weeks of probiotic product…
- Conditions
- Otitis Media With Effusion, Probiotics, Adenoid Vegetations
- Trial name
- NCT03277820
- Testing
- Probactiol Mini
- Where
- Belgium
- Volunteers
- 37 people
- Sponsor
- University Hospital, Antwerp
Otitis Media With Effusion, Eustachian Tube Disorder
Novel Imaging of the Eustachian Tube; Patient Study
The purpose of the study is to establish wether a contrast medium applied to the middle ear can be used to diagnose pathology in the auditory tube.
- Trial name
- CT-ET (NCT02282540)
- Testing
- Iodixanol to the Eustachian tube
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Bilateral Middle Ear Effusion Requiring Tympanostomy Tube Placement
OTO-201 for Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
The purpose of this study is to describe the safety and tolerability of two dose levels of OTO-201, placebo and sham when administered intra-operatively in pediatric subjects with bilateral middle ear effusion who require…
- Trial name
- NCT01755286
- Testing
- OTO-201
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Otonomy, Inc.
Otitis Media With Effusion
Clinical Study of the Tympanostomy Tube Delivery System
The objective of this investigational study is to evaluate the safety and performance of the Acclarent Tympanostomy Tube Delivery System (TTDS) for the placement of the Tympanostomy Tube [TT(s)] in patients indicated for such…
- Trial name
- inVENT (NCT00939796)
- Testing
- Acclarent Tympanostomy Tube Delivery System
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Integra LifeSciences Corporation
Otitis Media With Effusion, Adenoid Hypertrophy
The Effects of Exosomes in Otitis Media With Effusion
The particularity of adenoids, as a reservoir of bacterial pathogens and immune molecules, is known to be significantly involved in children with otitis media with effusion (OME).
- Trial name
- NCT05402267
- Testing
- Adenoidectomy
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Otitis Media With Effusion
Adenoidectomy for Otitis Media in 2-3 Year Old Children
The purpose of this study is to evaluate the efficacy of three different surgical treatments (1. Bilateral myringotomy and tube insertion (M\&T); 2. Adenoidectomy and bilateral myringotomy (A\&T); 3.
- Trial name
- NCT00016497
- Testing
- bilateral myringotomy, bilateral myringotomy and tubes, adenoidectomy
- Where
- United States
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Otitis Media Acute
Clinical Development of Deep Learning for the OtoSight
The objective of this study is to clinically develop and evaluate a machine learning approach to improve the performance and data interpretation of the PhotoniCare OtoSight Middle Ear Scope in pediatric patients presenting at the…
- Trial name
- NCT04722770
- Testing
- PhotoniCare OtoSight Middle Ear Scope
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- PhotoniCare, Inc.
Otorrhea, Otitis Media With Effusion in Children
Otiprio Versus Ciprodex Tympanostomy Tube Outcomes
Otolaryngologists routinely administer ear drops at the time of tympanostomy tube placement in order to prevent tube otorrhea; however, there is a lack of consensus as to which drops are the most effective, and whether a…
- Trial name
- NCT03347461
- Testing
- Otiprio, Ciprodex
- Where
- United States
- Sponsor
- Boston Medical Center
Otitis Media, Otitis Media With Effusion After Nasopharyngeal Carcinoma
Intranasal Corticosteroid Spray for Preventing Otitis Media With Effusion After Radiotherapy in Nasopharyngeal Carcinoma
This study focuses on a common side effect experienced by many patients after radiation therapy for nasopharyngeal cancer, which is a type of head and neck cancer.
- Conditions
- Otitis Media, Otitis Media With Effusion After Nasopharyngeal Carcinoma, Radiotherapy Side Effects, Radiotherapy Side Effect
- Trial name
- NCT07189572
- Testing
- Triamcinolone Acetonide
- Volunteers
- 168 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Secretory Otitis Media
A Comparison of Surgical and a New Non-Surgical Treatment Methods for Secretory Otitis Media in Children
Secretory otitis media (SOM) or middle ear effusion is a common finding affecting children in the age of 4-5 years. It is usually associated with 5-15 deci Bells hearing loss.
- Trial name
- NCT02546518
- Testing
- Moniri Otovent, Tympanostomy tube in the ear drum
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Vastra Gotaland Region
Otitis Media With Effusion
Adenoidectomy, Myringotomy and Tubes' Insertion vs Adenoidectomy and Myringotomy Alone in Children With Otitis Media With Effusion and Adenoid Hypertrophy
It is not unusual for several children operated for severe adenoid hyperthrophy causing breathing problems to have otitis media with effusion simultaneously.
- Trial name
- NCT00629694
- Testing
- adenoidectomy, myringotomy, tubes insertion, A-M
- Where
- Greece
- Volunteers
- 52 people
- Sponsor
- Aghia Sophia Children's Hospital of Athens
Otitis Media in Children, Chronic Otitis Media With Effusion
Posterior vs. Anterior Tympanostomy Tube Placement
The goal of this randomized clinical trial is to compare the results of ear tube placement in two different parts of the ear drum. The ear drum can be divided into four parts (called quadrants).
- Conditions
- Otitis Media in Children, Chronic Otitis Media With Effusion, Recurrent Acute Otitis Media
- Trial name
- NCT06191562
- Testing
- Tympanostomy tube
- Where
- 2 sites in United States
- Volunteers
- 386 people
- Sponsor
- David Chi, MD
Otitis Media in Children, Cleft Palate Children
Respiratory Tract Microbiome and Probiotics in Children With Cleft Palate
Otitis media with effusion (OME) involves fluid accumulation in the middle ear without infection, sometimes causing discomfort and hearing loss in children.
- Trial name
- NCT06505330
- Testing
- Probactiol Baby
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Otitis Media With Effusion in Children, Hearing Loss
Hearing Improvement After Making a Hole Surgically in Eardrum With or Without Ventilation Tube in Children With Glue Ears
The goal of this clinical trial is to compare the effectiveness of myringotomy with ventilation tube insertion to myringotomy alone in improving hearing in children with glue ear.
- Trial name
- NCT06909084
- Testing
- Myringotomy with ventilation tube, Myringotomy alone
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Chronic Eustachian Tube Dysfunction, Chronic Recurrent Otitis Media
Balloon Eustachian Tuboplasty in Treatment of Chronic Eustachian Tube Dysfunction
The prevalence of Eustachian tube (ET) dysfunction in adults reaches 1%. It causes a feeling of fullness in the ear, otalgia and hearing loss and can lead to recurrent acute otitis media, development of chronic otitis media with…
- Conditions
- Chronic Eustachian Tube Dysfunction, Chronic Recurrent Otitis Media, Effusion After Tympanostomy
- Trial name
- NCT03556215
- Testing
- Eustachian tube dilatation device, Myringotomy
- Where
- 2 sites in Czechia
- Volunteers
- 55 people
- Sponsor
- University Hospital Ostrava
Otitis Media
Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present
To determine whether the use of topical otic drops intra-operative and post-operative during tympanostomy tube placement reduces the rate of tympanostomy tube occlusion and post-operative otorrhea (ear drainage) during the…
- Trial name
- NCT03655665
- Testing
- Ofloxacin otic solution
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Children's Hospital
Middle Ear Effusion, Tympanic Membrane Perforation
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects Their Babies From Ear Disease
PneuMum is a randomised controlled trial that aims to find out if pneumococcal vaccination for Australian Indigenous mothers, in the last few months of pregnancy or at delivery, can prevent ear disease in infants.
- Conditions
- Middle Ear Effusion, Tympanic Membrane Perforation, Acute Otitis Media, Pneumococcal Infections
- Trial name
- NCT00310349
- Testing
- 23 valent pneumococcal polysaccharide vaccine
- Where
- Australia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Otitis Media With Effusion
Study of Anti-reflux Medication as a Potential Treatment for Glue Ear in Children
The accumulation of fluid behind the ear drum without any acute inflammation is known as otitis media with effusion (OME). It is the most common cause of acquired hearing loss during childhood.
- Trial name
- NCT01082029
- Testing
- Lansoprazole
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Hamilton Health Sciences Corporation