Clinical trials: Otolaryngology
Sinusitis, Otitis
Complicated Infections in Otorhinolaryngology
This observational study aims to learn more about complicated infections treated by otorhinolaryngologists. The main questions to answer are: What is the management of complicated sinonasal infections in Ljubljana, Slovenia, What…
- Conditions
- Sinusitis, Otitis, Laryngitis, Lymphadenitis
- Trial name
- ENT_infect (NCT06023550)
- Testing
- Treatment with surgery and/or conservative measures
- Where
- Slovenia
- Volunteers
- 2,550 people
- Sponsor
- University Medical Centre Ljubljana
Acute Bacterial Sinusitis
Single Use Device Endoscopy for the Diagnosis of Acute Bacterial Rhinosinusitis in Primary Care
This is a pilot study to assess the first time use of the JGG endoscope® in humans and in primary care. The JGG endoscope® is attached to a Heine® otoscope and allows to inspect and to collect samples from the middle meatus of…
- Trial name
- Sinus-Endo (NCT03766568)
- Testing
- JGG endoscope(R)
- Where
- 6 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Dominik Glinz
Thyroidectomy
The Impact of Post-thyroidectomy Neck Stretching Exercises on Improving Short Term Quality of Life
The project deals with patients undergoing surgery in the neck due to benign tumor in the thyroid gland in order to remove pressure symptoms. The background of the project is a recent series of studies (Sorensen, Watt et al.
- Trial name
- NCT04645056
- Testing
- Stretching and Mobility exercises for neck and shoulder
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Adenotonsillectomy, Analgesia
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity
The goal of this study is determine if an oral systemic course of steroids is a safe and effective option in lowering pain and complications following adenotonsillectomy in various pediatric age groups.
- Conditions
- Adenotonsillectomy, Analgesia, Surgery
- Trial name
- NCT04879823
- Testing
- Dexamethasone, Ibuprofen, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 222 people
- Sponsor
- David Chi, MD
SARS-CoV Infection, COVID-19
Malaysian COVID-19 Anosmia Study (Phase 1) - A Nationwide Multicentre Cross-Sectional Study
The Malaysian COVID-19 Anosmia Study is a nationwide multicentre observational study to investigate the prevalence and characteristics of olfactory and gustatory/taste disturbances in COVID-19 infection in Malaysia, and to…
- Conditions
- SARS-CoV Infection, COVID-19, Anosmia, Dysgeusia
- Trial name
- NCT04390165
- Testing
- Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
- Where
- 14 sites in Malaysia
- Volunteers
- 498 people
- Sponsor
- Hospital Sultanah Bahiyah
Anesthesia
Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI)
The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing suspension laryngoscopy on general anesthesia.
- Trial name
- NCT01796210
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Emmanuel Boselli
Cancer of the Upper Aero-digestive Tract, Alcoholism
Alcohol Addiction and Otorhinolaryngology Cancer
The aim of the study is to compare the hospitalisation period in ORL surgery for two groups of patients. One of them will be treated for alcohol addiction to weaning them before the surgery ORL.
- Trial name
- NCT00825448
- Testing
- Hospitalization for a week
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Department of Clinical Research and Innovation
Anxiety, Consumer Satisfaction
Effect of Preoperative Information to Parents Before Ear-nose-throat Pediatric Surgery
Children who will have surgery and need anesthesia, and their parents are often anxious and show signs of stress and discomfort.
- Trial name
- NCT03763292
- Testing
- Specific information brochure
- Where
- Norway
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Hearing Loss, Sensorineural, Hearing Loss, Cochlear
The Neuro Zti Cochlear Implant System Efficacy and Safety in Adults
The purpose of the study is to assess the efficacy and the safety profile of the Neuro Cochlear Implant System (CIS) in adults with severe-to-profound hearing loss.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Cochlear, Deafness
- Trial name
- NCT02941627
- Testing
- Neuro Zti, Neuro One
- Where
- 6 sites in Canada, Denmark
- Volunteers
- 53 people
- Sponsor
- Oticon Medical
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Workplace Violence, Perceived Safety
Workplace Violence and Safety Perception Among ENT Physicians in Turkey
This multicenter, cross-sectional survey study aims to evaluate the perceived level of safety and security against workplace violence among otolaryngology-head and neck surgery (ENT-HNS) physicians in Turkey.
- Conditions
- Workplace Violence, Perceived Safety, Occupational Health, Otolaryngology-Head and Neck Surgery Physicians
- Trial name
- NCT07311629
- Testing
- Online Survey Questionnaire
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Hearing Loss, Head and Neck Neoplasms
NIDCD Otolaryngology Clinical Protocol Biospecimen Bank
Background: Many disorders of the head and neck can affect a person s hearing; balance; smell; taste; swallowing; voice; or speech. These disorders include cancers and genetic and inflammatory diseases.
- Conditions
- Hearing Loss, Head and Neck Neoplasms, Hearing Disorders, Laryngeal Disease
- Trial name
- NCT06303180
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Otorhinolaryngologic Diseases
Evaluation of Office-Based Sheathed Flexible Nasopharyngoscopy
The processing of standard flexible nasopharyngoscopes is a time-consuming and costly process. The goal of this study is to determine the efficiency and cost-effectiveness of sheathed flexible endoscope in an office setting.
- Trial name
- NCT01669278
- Testing
- Endosheath
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Oropharynx Carcinoma
An Observational Study of Clinical Treatments for Patients With Oropharyngeal Carcinoma
This is a prospective, observational study evaluating the effect and efficiency of different clinical treatments for patients with oropharyngeal carcinoma (OPC).
- Trial name
- NCT05341479
- Testing
- Surgery for early-stage OPC, RT for early-stage OPC, CRT for advanced OPC
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Radiotherapy, Conformal (IMRT), Head and Neck Cancer
Contribution of the ENT (Ear, Nose, and Throat) Surgeon's Clinical Evaluation to the Contouring of Target Volumes and Organs Eligible for Radiotherapy in Head and Neck Cancers
Radiotherapy (RT), surgery and chemotherapy (CT) are treatments for head and neck cancers, used alone or in combination. Conformal RT with Intensity Modulation (IMRT) is currently the reference technique.
- Conditions
- Radiotherapy, Conformal (IMRT), Head and Neck Cancer, Otolaryngology, Surgeons
- Trial name
- CONTOUR (NCT03265873)
- Testing
- Systematic consideration of the advice of the ENT surgeon in the determination of the radiotherapy target volumes in head and neck cancers.
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Adults Undergoing Otorhinolaryngology Surgery
Intravenous Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation in Adult Otorhinolaryngologic Surgery
The goal of this clinical trial is to learn whether intravenous magnesium sulphate can reduce emergence agitation as effectively as intravenous dexmedetomidine in adult patients undergoing otorhinolaryngology surgery under…
- Trial name
- NCT07544173
- Testing
- Magnesium sulphate, Dexmedetomidine
- Where
- Indonesia
- Volunteers
- 64 people
- Sponsor
- Universitas Indonesia
Ear Infection, Telemedicine
Examination of the Applicability and Performance of Otolaryngology Telemedicine, Telediagnostics in Establishing the Diagnosis and Therapy of Otolaryngology Diseases
System/Device name: Otoscopic recording and clinical data telemedicine software supporting its transmission and analysis. Characteristics of the medical device: The device is applied to an iPhone with a CE mark also from a…
- Trial name
- TMED_FOG_001 (NCT06781164)
- Testing
- telemedicine
- Where
- Hungary
- Volunteers
- 103 people
- Sponsor
- Szeged University
Sensory Hearing Loss, Sensorineural Hearing Loss
The SeaSHeL National Prospective Cohort Study
Each year, approximately 15,000 people in the United Kingdom experience sudden loss of hearing that is sensorineural in nature. In the majority of cases, the cause is unknown despite investigation, and these cases are termed…
- Conditions
- Sensory Hearing Loss, Sensorineural Hearing Loss, Sensorineural Hearing Loss in Left Ear, Sensorineural Hearing Loss in Right Ear
- Trial name
- SeaSHeL (NCT04108598)
- Testing
- Quality of life questionnaire
- Where
- United Kingdom
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- University College, London
Tinnitus
Commercial Lidocaine Patch as a Treatment for Ear-ringing
The purpose of this investigation is to evaluate if topically applied lidocaine, in the form of lidocaine patches, reduces the burden of chronic subjective tinnitus in a consistent and measurable way.
- Trial name
- NCT02088866
- Testing
- Transdermal Lidocaine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Pain, Postoperative
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
The purpose of this study is to find out which pain medication is more effective in reducing pain after nose surgery (rhinoplasty).
- Trial name
- NCT07689162
- Testing
- Standard Bupivacaine, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Washington University School of Medicine