Clinical trials: Otologic Disease
Hearing Loss, Cancer
Study to Evaluate the Safety and Pharmacokinetics of SPI-1005
A study to determine the safety, tolerability, and pharmacokinetics of SPI-1005 capsules in healthy adults.
- Trial name
- NCT01452607
- Testing
- SPI-1005
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sound Pharmaceuticals, Incorporated
Hearing Loss, Sensorineural
PC-Based Rehabilitation of Auditory Function
Many older subjects experience difficulty in understanding speech in noisy environments. Part of this problem is related to changes that occur in the ear with age and compromise the hearing of high-pitched sounds.
- Trial name
- CINT (NCT00724347)
- Testing
- Consonant Identification Training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hearing Loss
Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2019_04
Participants will take part in both a passive and active emotion recognition task: (1) passively listening to semantically-neutral sentences with emotional prosody, and (2) actively listening and subsequently categorizing…
- Trial name
- NCT03992963
- Testing
- Hearing Aid without frequency lowering enabled, Hearing Aid with frequency lowering enabled
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Sensorineural Hearing Loss
Cochlear Implanted Listening Effort and Hearing Attention
Cochlear implant users perceive mainly sound amplitude modulation cues. Processing of these amplitude modulations can be subject to interferences, so that the perception of a modulation in a target sound can be impaired by a…
- Trial name
- EffICAtt (NCT04733950)
- Testing
- Forced choice psychoacoustic task for the evaluation of modulation detection performance and selective auditory attention. (for both arm), Measurement of the pupil diameter for the evaluation of listening effort during speech perception
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hearing Loss, Age-Related
Early Identification of Age-related Hearing Impairment
The need for future hearing rehabilitation is enormous. World Health Organization (WHO 2021) has estimated that by 2050, 2.5 billion people will have some degree of hearing loss, and 1/4 of them will require hearing…
- Trial name
- NCT06418321
- Testing
- Investigational device, Audiometer, Otomicroscopy
- Where
- 2 sites in Finland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Aalto University
Deafness
Assessing the Impact of Vidéo Remote Sign Language Interpreting in Healthcare
This is a randomise study that looks at what is the effectiveness of the VRI system in improving communication outcomes between Deaf patients and doctors versus the 'available standard of care of the usual communication tools…
- Trial name
- Impact of VRI (NCT05966623)
- Testing
- Video Remote Interpretation
- Where
- 2 sites in Colombia
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Hearing Loss
A Comparative Clinical Investigation of Musician's Preference With Hearing Aids
For this study, Bernafon AG will carry out testing with participants with hearing loss to compare a dedicated music program to a general listening program.
- Trial name
- BF007-2101 (NCT04939259)
- Testing
- New Music Program, Standard Listening Program
- Where
- Switzerland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Bernafon AG
Hearing Loss, Hearing Impaired Children
Audiobooks for Hearing Loss App as Auditory Training
The goal of the proposed project is to create an Audiobooks for Hearing Loss (HL) App - an audiobook App that has a wide array of user-selectable features designed to provide auditory training.
- Conditions
- Hearing Loss, Hearing Impaired Children, Hearing Impairment
- Trial name
- NCT04231396
- Testing
- Audiobooks for hearing loss App
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- BioSpeech
Auditory Processing Disorders
Contribution of Functional MRI in Assessment of Auditory Processing Disorders
Auditory Processing Disorder (APD) affects 0.5-7% of the pediatric population. This disorder is responsible for a child's low hearing ability.
- Trial name
- IRMf-TTA (NCT03887182)
- Testing
- functional MRI, Automated Cortical Brainstem Auditory Evoked Potential, whole exome sequencing
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hearing Loss, Conductive
Audiological Benefit With Non-implantable Bone Conduction Hearing Systems
Recently, a new non-invasive bone conduction hearing aid was introduced. The system is connected directly to the skin with an adhesive adapter to transmit the sound to the inner ear through bone vibrations.
- Trial name
- NCT03129191
- Testing
- Non-invasive bone conduction hearing aid A, Non-invasive bone conduction hearing aid B
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hearing Loss
Evaluating the Revised WORQ in CI Users
The Work Related Questionnaire (WORQ) is a 59-item questionnaire of which each item represents an International Classification of Functioning and disability category.
- Trial name
- NCT04602780
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Vestibular Disorder, Neurodevelopmental Disorders
BALANCED GROWTH: The Involvement of the Vestibular System in a Child's Cognitive and Motor Development
When a vestibular dysfunction occurs at birth or in early stages of life, one might expect that this may have an enormous impact on a child's development.
- Trial name
- NCT04685746
- Testing
- Balanced Growth Protocol
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Ghent
Noise-induced Hearing Loss
Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL)
This prospective study is a randomized, double-blind, placebo-controlled Phase 3 clinical trial of oral D-methionine (D-met) to reduce noise-induced hearing loss (NIHL) and tinnitus.
- Trial name
- NCT02903355
- Testing
- D-methionine
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University
Tinnitus
Tinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template Development
The study is designed to identify specific patterns of brain functional activity associated with chronic, moderate to severe tinnitus through the use of resting-state MEG scans.
- Trial name
- NCT01185990
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Orasi Medical, Inc.
Degenerative Diseases of the Central Nervous System, Ocular-motor and Vestibular Diseases
Neural Mechanisms Engaged in Control of Eye Movements
The purpose of eye movements is to ensure clear, optimal vision. In order to see clearly, images must be held steady on the retina.
- Trial name
- NCT00999934
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Tinnitus
Peripheral-central Correlation Study on the Treatment of Chronic Tinnitus With "Dao qi Tong Luo" Based on the Theory of "Connecting the Two Ears to the Brain"
By comparing the clinical manifestations, ABR parameters and cerebral cortex blood oxygen levels of chronic tinnitus patients and healthy subjects under two different body states, the peripheral-central correlation of chronic…
- Trial name
- NCT06401993
- Testing
- The "dao qi tong luo" group, The acupuncture group
- Where
- China
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Congenital Hypothyroidism, Hearing Loss
The Prevalence of Hearing Loss Among Children With Congenital Hypothyroidism
Congenital hypothyroidism (CH) occurs in 1:4000 live births. Neurological disturbances like speech delay, motor delay and lower IQ were reported in children with CH.
- Trial name
- NCT01223638
- Testing
- Audiometry
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Old Age, Vestibular Disorder
Comparative Effects of Virtual Reality and Vestibular Exercises on Balance Gait in Older Adults
To compare the effects of virtual reality and vestibular exercises on balance, gait, and activities of daily living in older adults.
- Conditions
- Old Age, Vestibular Disorder, Balance, Exercise
- Trial name
- NCT06407726
- Testing
- virtual reality training group, vestibular exercise group
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cochlear Hearing Loss
MeasurIng and Restoring Auditory Awareness for Cochlear Implant Listeners in noisE
The goal of this interventional study is to describe how people with cochlear implants perceive the perceive speech in noise and their sound environment on adults who are native French speakers with typical hearing or with…
- Trial name
- MIRACLE (NCT06420921)
- Testing
- Speech in noise comprehension test, Objective tests of perception of ambient sound cues in noise, Subjective tests of perception of ambient sound cues in noise
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Tympanosclerosis, Thickened Ears
The Effects of Glycerol as an Optical Clearing Agent for Visualization of the Middle Ear
This study will examine the improvement in middle ear optical coherence tomography imaging from the topical application of glycerol to the tympanic membrane in normal, opaque and post-operative ears
- Conditions
- Tympanosclerosis, Thickened Ears, Healthy, Surgery
- Trial name
- NCT05497934
- Testing
- Glycerol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority