Clinical trials: Outbreaks
Critical Illness, Sars-CoV2
Anxiety and Work Resilience Among Tertiary University Hospital Workers During the COVID-19 Outbreak: An Online Survey
For limiting COVID-19 spreading, the World Health Organisation (WHO) recommended worldwide confinement on 2010. In France, unessential institutions were closed on March 14th and population confinement was decided on March 17th.
- Conditions
- Critical Illness, Sars-CoV2, SARS Pneumonia, Coronavirus Infection
- Trial name
- PSY_CO_CHU (NCT04358640)
- Where
- France
- Volunteers
- 1,784 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Coronavirus Infection
Prevention of Coronavirus Disease (COVID-19) Outbreaks With Nitazoxanide
The new coronavirus outbreak has led to a public health emergency of international concern, putting all health organizations on high alert.
- Trial name
- NCT04406246
- Testing
- Nitazoxanide 500Mg Oral Tablet
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
Meningococcal Serogroup B
Pilot Study of the Immunogenicity, Reactogenicity and Tolerability of Two Schedules of a 4CmenB Vaccine in Adolescents and Young Adults
The overall aim of this study is to determine if an accelerated "Bexsero® (Multicomponent meningococcal B vaccine)" schedule compared to a standard schedule is immunogenic, safe, and tolerable, in order to increase capacity for…
- Trial name
- NCT02583412
- Testing
- Bexsero®, Havrix®
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Canadian Immunization Research Network
STEMI - ST Elevation Myocardial Infarction
Thrombolysis in STEMI Patients Compared With pPCI on Recanalization Time in the Context of the COVID-19 Outbreak.
During the outbreak of COVID-19, for patients with acute ST-segment elevation myocardial infarction with unclear infection, the time of primary PCI is uncertain, and it is often expected to exceed 90 minutes or even 120 minutes.
- Trial name
- RESCUE-STEMI (NCT05354128)
- Testing
- Thrombolytic, percutaneous coronary stenting
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Ya-Wei Xu
Outbreak Investigation
Leveraging Social Innovation and Community-Engagement to Reduce Disparities in Outbreak Control Outcomes
This study evaluates the impact of an intervention to increase viral transmission behaviors. The intervention will be developed through a crowdsourcing contest.
- Trial name
- NCT05123729
- Testing
- Crowdsourced campaign package, Rapid Response Teams, Registry enrollment
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Depression, Burnout, Professional
Health cAre woRkers exposeD to COVID-19
Health care workers working in hospital or nursing home for elderly people involved in the coronavirus epidemic are facing several challenges such as direct exposure and involvement in the resolution of major public health…
- Conditions
- Depression, Burnout, Professional, Post Traumatic Stress Disorder
- Trial name
- HARD-COVID19 (NCT04570202)
- Testing
- EMDR
- Where
- 2 sites in France
- Volunteers
- 900 people
- Sponsor
- University Hospital, Tours
Attitude to Health, Behavior, Health
Creating a New Health Promotion Module to Help the Indigenous People of Selangor Prepare for Disease X and Outbreaks
The goal of this cluster randomized trial is to develop and test a new method for preparing indigenous (locally termed as Orang Asli) households in Selangor, a state in Malaysia, for outbreaks and Disease X, a potential unknown…
- Conditions
- Attitude to Health, Behavior, Health, Health Behavior, Health-Related Behavior
- Trial name
- NCT06539845
- Testing
- Outbreak Preparedness Intervention for the Orang Asli, Educational Brochures for the Orang Asli
- Where
- 2 sites in Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
COVID 19, SARS-Cov-2
Combination of Chest Scanography and Nasal Viral Detection Test to Detect COVID-19 Positive Patients Before Surgical Intervention in a University Hospital During Coronavirus Pandemia
This research aims to improve the screening for COVID-19 upon admission to the Montpellier University Hospital for an act under general anesthesia or at high risk of transmission of the virus.
- Trial name
- COVID-Scan (NCT04355715)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Pneumonitis, Coronavirus Infection
Proflaxis Using Hydroxychloroquine Plus Vitamins-Zinc During COVID-19 Pandemia
Healthcare professionals mainly doctors, nurses and their first degree relatives (spouse, father, mother, sister, brother, child) who have been started hydroxychloroquine(plaquenil) 200mg single dose repeated every three weeks…
- Trial name
- NCT04326725
- Testing
- Plaquenil 200Mg Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istinye University
Covid19
Study of COVID-19 Outbreak in Hospital Departments of Bamako, Mali
The new coronavirus known as SARS-Cov-2 (severe acute respiratory syndrome -coronavirus 2) was first reported in December 2019 and rapidly became a public health emergency.
- Trial name
- BAMACOV (NCT04710316)
- Testing
- SARS-CoV-2 screening by molecular biology, Serological screening
- Where
- 4 sites in Mali
- Volunteers
- 450 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Mental Health Wellness 1
The Psychological Impact of COVID-19 Outbreak on COVID-19 Survivors and Their Families
Patients with COVID-19 diagnoses are treated under isolation in hospitals and with high-stress level. Currently, there is little information on the mental health implications of exposure amongst COVID-19 survivors and their…
- Trial name
- NCT04365348
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- The University of Hong Kong
SLE
Telemedicine for Follow-up of Systemic Lupus Erythematosus
Background Patients with systemic lupus erythematosus (SLE) might be more susceptible to Covid-19 due to the underlying disease, co-morbidities and the use of immunosuppressive drugs.
- Trial name
- NCT04368299
- Testing
- Telemedicine, Standard care
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- Chinese University of Hong Kong
Pneumonia, Necrotizing, Lung Abscess
Complicated Pneumonia (CP) in Children in South-East Europe
This retrospective observational study aims to evaluate clinical course of complicated community acquired pneumonia in children, particularly focusing on necrotizing pneumonia cases, as well as determination of etiological agents…
- Conditions
- Pneumonia, Necrotizing, Lung Abscess, Empyema, Pleural
- Trial name
- CP (NCT06657898)
- Where
- Serbia
- Volunteers
- 300 people
- Sponsor
- Aleksandar Sovtic
Osteoarthritis
COVID-19 in Osteoarthritis Patients
While the coronavirus pandemic has spread rapidly around the world, it has generated a considerable degree of fear, concern and anxiety among the population in general and among certain groups in particular, such as older…
- Trial name
- NCT04791462
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
SARS-CoV 2, COVID-19
Assessment of the Psycho-social Impact of COVID-19 Outbreak
It has been shown in previous important outbreaks of infectious diseases that they have a huge impact on individuals and communities.
- Conditions
- SARS-CoV 2, COVID-19, Quality of Life, Mental Health Wellness 1
- Trial name
- COM-COVID (NCT04378452)
- Testing
- COM-COVID anonimous survey
- Where
- 4 sites in Spain
- Volunteers
- 56,656 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Ebola Virus Disease
Community Preparedness for Outbreak Response and Readiness for Ebola Vaccination in Liberia
This community-based mixed methods study intends to identify, explore, and assess the determinants of community preparedness for outbreak situations, including acceptance for Ebola vaccines.
- Trial name
- NCT05888649
- Testing
- Community Clusters
- Where
- Liberia
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- UL-PIRE Africa Center
Cutaneous Leishmaniasis
Frequency of Parasite Infection in Hyraxes and Sandflies During Outbreak of Leishmania Tropica Epidemic in The West Bank
The objective of the project is to study the pathogenesis of Leishmania tropica infection in a focus of infection, to learn about relationship of infection in humans with ecological factors such as infection in hyraxes reservoir…
- Trial name
- NCT00737386
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Critical Illness, Covid19
Psychological Impact of COVID-19 Outbreak on Caregivers
Based on the experience of previous pandemics, countries reacted by applying different upgrade strategies to prevent or delay the widespread of the disease.
- Conditions
- Critical Illness, Covid19, Stress Disorders, Post-Traumatic
- Trial name
- PSY-CO-ICU (NCT04511780)
- Testing
- questionnaire filling
- Where
- 51 sites in France
- Volunteers
- 701 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hepatitis A, Human Immunodeficiency Virus
Effectiveness of Booster With 1 or 2 Doses of HAV Vaccine Among HIV-infected Patients
Though HAV is mainly transmitted through the fecal-oral route, infection by sexual intercourse and blood transfusion is also possible.
- Conditions
- Hepatitis A, Human Immunodeficiency Virus, Vaccine Response Impaired
- Trial name
- NCT03855176
- Testing
- Vaqta Injectable Product
- Where
- Taiwan
- Volunteers
- 153 people
- Sponsor
- National Taiwan University Hospital
Cardiovascular Death; Major Adverse Cardiovascular Events
2019-nCoV Outbreak and Cardiovascular Diseases
Cardiovascular events occurring after 2019-nCoV outbreak in Jinan were prospectively assessed by emergency physicians. We compared those events with events that occurred during the past 3 months and the same months of the last…
- Trial name
- NCT04255940
- Where
- 12 sites in China
- Volunteers
- 12,000 people
- Sponsor
- Qilu Hospital of Shandong University