Clinical trials: Outcome
Dementia
Sharing the Outcome of a Memory Assessment
The purpose of this study is to establish the acceptability of a guide developed to improve people's experiences of dementia assessment outcome appointments in comparison to a standard consultation.
- Trial name
- NCT04935060
- Testing
- A guide to inform the process of delivering the outcomes of a dementia assessment, Usual Care
- Where
- 2 sites in United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
The Primary Outcome is Preterm Delivery Before 28 Weeks Gestational Age Compared to Women With One vs Two Cerclages Placed
Single Versus Double Suture Cervical Cerclage to Prevent Preterm Birth
Cerclage placement is known to be beneficial in prevention of preterm birth when placed inn a certain subset of patients. Clinically, the number of sutures can also vary by surgeon preference to one or two sutures in one…
- Trial name
- NCT04742647
- Testing
- Double cerclage, Single cerclage
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Nephrotic Syndrome Steroid-Dependent, Nephrotic Syndrome Steroid-Resistant
Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics Study
Idiopathic Nephrotic Syndrome is a rare disease of the kidneys, which typically affects children. For most affected children there is the need of a prolonged treatment with drugs reducing the activity of the immune system, also…
- Conditions
- Nephrotic Syndrome Steroid-Dependent, Nephrotic Syndrome Steroid-Resistant, Nephrotic Syndrome in Children, Glomerulonephritis
- Trial name
- PRECISE (NCT06792448)
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Endothelial Dysfunction, Arterial Stiffness
The Role of Glycocalyx Integrity in the Primary Prevention of Major Cardiovascular Events
The researchers intend to recruit individuals who are referred for a routine screening in the primary prevention outpatient clinic of Attikon University hospital, Athens According to institutional protocols, a detailed medical…
- Trial name
- NCT04646252
- Testing
- Perfused Boundary Region of sublingual microvessels
- Where
- Greece
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Athens
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Cardiomyopathies
Outcome of Cardiomyopathic Adults Admission in ICU.
To study the outcome of the cardiac function, and clinical status of the patiants with cardiomyopathy who are admitted in the I.C.U.
- Trial name
- NCT05567445
- Testing
- Echocardiography, CBC, Liver function, kideny function
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University
Complication, Postoperative, Perioperative/Postoperative Complications
The Impact of Prehabilitation Bundle on Perioperative Outcome for Frail Elderly Patients Undergoing Major Abdominal Surgery
This study aims to study the efficacy of a preoperative "bundle" of interventions, which consists of preoperative physiotherapy, nutritional support and cognitive exercises on elderly frail patients undergoing major abdominal…
- Trial name
- NCT02921932
- Testing
- Ensure, Resource 2.0 and Glucerna, Cognitive Training, Memory Card Game, 'Threshold' Inspiratory Muscle Trainer, Respironics of New Jersey Inc
- Where
- Singapore
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Hearing Loss, Noise-Induced
Risk Factors for Hearing Loss as a Result of Exposure to Noise During Military Training in the IDF
As part of the proposed work, the investigators would like to examine whether there is a need to use a training video to train IDF combat soldiers to improve the use of ear plugs and to prevent hearing loss from exposure to…
- Trial name
- NCT03314116
- Testing
- Guidance on auditory protection
- Where
- Israel
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Stroke
Prognostic Value for Predicting Outcome Using Functional Near-infrared Spectroscopy in Stroke Rehabilitation
To investigate the prognostic value of Functional Near-Infrared Spectroscopy (fNIRS) in stroke rehabilitation with serial measurements.
- Trial name
- NCT04288414
- Testing
- functional near-infrared spectroscopy
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Gastric Distention
High-Flow Heated and Humidified Oxygen Therapy and Gastric Distension
High Flow Heated and Humidified Nasal Oxygen therapy (HFHHNO) has been increasingly used in emergency medicine to assist patients with short term respiratory failure and to provide adequate oxygen to the body prior to intubation.
- Trial name
- HFHHNOGastric (NCT03134937)
- Testing
- High-Flow Heated and Humidified Oxygen Therapy (HFHHNO)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Anorexia Nervosa
Assessment of the Impact of Early Treatment for Anorexia Nervosa in a Day Hospital on Food Symptomatology, the Outcome of Young Patients, and the Family Experience
During the management of chronic illnesses, the day hospital (DH) serves as a brief and effective alternative to traditional hospitalization, offering access to multidisciplinary care.
- Trial name
- EVA-FAM (NCT06218472)
- Testing
- Day Hospital Treatment, Multidisciplinary follow-up "as usual" within the service, Conduct semi-structured qualitative interviews
- Where
- France
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
BRCA1 Mutation, POLD1 Gene Mutation
An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results
The purpose of this study is to examine the impact of new cancer genetic counseling models that aim to increase patient engagement with the genetics team.
- Conditions
- BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation, BRCA2 Mutation
- Trial name
- NCT05420064
- Testing
- Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care
- Where
- 8 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Major Depressive Disorder
Predictors of Treatment Outcome With Cognitive Behavioral Therapy for Depression
The purpose of this research study is to learn whether specific types of brain imaging and psychological testing can predict how much benefit patients with depression will receive from a well-studied psychotherapy for depression…
- Trial name
- NCT01922219
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Clinical Pregnancy, Embryo Implantation
DNA Amplification in Blastocoel Fluid
Introduction: Although innovative procedural changes in frozen embryo transfer (FET) cycles have increased the implantation rate of blastocysts transferred significantly, blastocyst selection remains a significant limiting factor…
- Trial name
- NCT04744844
- Testing
- blastocoel fluid biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Antalya IVF
Ecchymosis, Adverse Anesthesia Outcome
Comparison of Lidocaine With and Without Adrenaline for Reducing Ecchymosis
This randomized, double-blinded controlled trial evaluates whether lidocaine with adrenaline reduces bruising (ecchymosis) more effectively than lidocaine without adrenaline among women undergoing contraceptive implant insertion…
- Conditions
- Ecchymosis, Adverse Anesthesia Outcome, Complications Associated With Device, Bleeding
- Trial name
- CLEAR (NCT07897201)
- Testing
- 1% Lidocaine with adrenaline, 1% Lidocaine
- Where
- Thailand
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Kidney Disease, End-Stage
Electronic Patient-Reported Outcomes in Clinical Kidney Practice (ePRO Kidney)
People living with end-stage kidney disease (ESKD) need dialysis or transplantation in order to stay alive. This illness and treatment significantly impact peoples' health, emotions, work and relationships.
- Trial name
- NCT03149328
- Testing
- Educational Support
- Where
- 2 sites in Canada
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Postoperative Pulmonary Complications (PPCs), Feasibility Studies
PROtective Ventilation With FLOW-Controlled Ventilation
The investigators want to investigate in patients undergoing robot-assisted laparoscopic surgery (a minimally invasive procedure) how applicable flow-controlled ventilation is, and whether it might also be safer than the current…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Feasibility Studies, Pilot Study
- Trial name
- PROFLOW (NCT06703814)
- Testing
- Intraoperative flow-controlled ventilation strategy, Intraoperative pressure-controlled ventilation strategy
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Tissue Oxygenation
The Correlation Between Tissue Oxygenations Using NIRS and Clinical Outcomes in Very Preterm Infants.
With the development of neonatal critical medicine, the survival rate of premature infants has gradually increased, and the incidence of late complications has significantly decreased, but preterm delivery is still the main cause…
- Trial name
- TCBTOUNACOIVPI (NCT06483867)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Urinary Bladder Trauma
Managment and Outcome of Urinary Bladder Trauma After Gynaecological and Obstetric Operations
We aimed to evaluate the management and outcome of bladder trauma after gynecological and obstetric operations at Assiut university hospital and to evaluate the methods of treatment of these complications.
- Trial name
- NCT06147804
- Testing
- Surgical managment of Urinary bladder trauma after gynaecological and obstetric operation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Adult Respiratory Distress Syndrome
ACE Gene Polymorphism and ARDS Outcome
The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory failure with a high mortality rate. The mechanism of resolution of the late organizing phase remains uncertain.
- Trial name
- NCT00155779
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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