Clinical trials: Outcome Measure
Depression, Anxiety, Post-traumatic Stress Symptoms
Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
The goal of this clinical trial is to evaluate which factors influence the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy for depressive symptoms in real-world settings in Italy.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Symptoms, Dissociation, Psychotherapy Research and Outcome Measures
- Trial name
- PROCESS-EMDR (NCT07033741)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Neuromuscular Disease
Development of a Proxy Motor Outcome Measure in Young Children With Neuromuscular Disease
Patient reported outcomes (PROs) instruments are often used to measure meaningful treatment benefit or risk in clinical trials. PROs allow patients voices to be heard in ways that assist healthcare clinicians to address treatment…
- Trial name
- NCT02007213
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Psychological Distress
Validation of the Spanish Version of the Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM) in Chile
AIM: study the psychometric properties of the Spanish version of the Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM), an instrument that measures psychological distress, in the Chilean population.
- Trial name
- NCT04122079
- Where
- Chile
- Volunteers
- 1,120 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Abdominal Surgery
Development of a Patient-Reported Outcome Measure to Assess Recovery After Abdominal Surgery
As surgery enters the era of value-based care, it is advocated that postoperative recovery be measured using patient-reported outcomes (PROs) as they provide a mean to incorporate the patient's perspectives and experiences into…
- Trial name
- NCT03461497
- Where
- 7 sites in United States, Brazil and 3 more
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Ovarian Cancer, Breast Cancer
Comprehensive Outcomes for After Cancer Health
This study intends to explore feasibility, acceptability, and outcomes related to the use of a digital health coaching intervention for individuals who have completed primary therapy for cancer.
- Conditions
- Ovarian Cancer, Breast Cancer, Lung Cancer, Gastric Cancer
- Trial name
- COACH (NCT05349227)
- Testing
- Digital Health Coaching Program, Fitbit
- Where
- 7 sites in United States
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Pack Health
Charcot-Marie-Tooth Disease Type 1A
Tools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers
This is a 2-year follow-up study of a cohort of 60 CMT1A patients. The objective is to identify markers allowing to better understand the phenotypic variability observed on patients with CMT1A, to identify predictive markers of…
- Trial name
- CMT-TOOLS (NCT02596191)
- Testing
- Clinical evaluation, electrophysiological record, Muscle MRI
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Traumatic Brain Injury
Brain Injury Assessment Study at Hennepin County Medical Center
The goals of this study are to develop an objective, multi-modal classification scheme and outcome measures for traumatic brain injury based on several measures: (1) blood-based biomarkers (indicates which cell types are…
- Trial name
- BASH (NCT02706574)
- Volunteers
- 774 people, healthy volunteers welcome
- Sponsor
- CentraCare
Overactive Bladder, Overactive Bladder Syndrome
Experience Sampling Method in OAB Patients
Rationale: The overactive bladder syndrome is diagnosed clinically by using the ICS criteria of ≥8 micturitions and at least 1 urgency episode per 24 hours.
- Trial name
- NCT03435991
- Testing
- Validation Experience Sampling Method 'Uromate'
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Head and Neck Cancer
Study to Explore Post Surgical Outcomes Using Point-of-Gaze, Electromyography and Elastography of the SCM
The side effects following post surgical neck dissection treatment for tumours in the head and neck (HN) region are weakness of the shoulder and neck muscles, numbness and reduced sensation around the neck and shoulder region and…
- Trial name
- NCT05059340
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Low Back Pain, Degeneration of Lumbosacral Intervertebral Disc
The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures
The purpose of this study is to compare changes in spinal stiffness and back muscle activity between spinal manipulative therapy (SMT) responders, non-responders and asymptomatic participants.
- Conditions
- Low Back Pain, Degeneration of Lumbosacral Intervertebral Disc, Muscle Weakness, Spine Stiffness
- Trial name
- NCT01761838
- Testing
- SMT for low back pain patients, Pain induction (optional), Low back pain participants without SMT
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Myotonic Dystrophy Type 2
Clinical Outcome Measures in Myotonic Dystrophy Type 2
A monocentric, longitudinal, observational case-control study in patients with Myotonic Dystrophy type 2 (DM2). At least 60 DM2 will be evaluated through a battery of patients reported Outcomes (PROs) and clinical Outcome…
- Trial name
- COMEDY-2 (NCT03603171)
- Testing
- DM1-ActivC, R-PAct, Beck depression inventory
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Benedikt Schoser
Irritable Bowel Syndrome
Experience Sampling Method for Symptom Assessment in Irritable Bowel Syndrome
Reliable patient reported outcome measures (PROM's) for symptom assessment in irritable bowel syndrome are essential in order to investigate natural disease course and potential treatment options aimed at symptom improvement…
- Trial name
- NCT02880722
- Where
- Netherlands
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy
Multi-country Study- Effect of Dietary Fats on Fat Deposition
There is existing evidence to show that vegetable oils having unsaturated fatty acids in the sn-2 position with predominantly palmitic acid (C16:0) or stearic acid (C18:0) in the sn-1 and sn-3 positions of fat molecules do not…
- Trial name
- NCT02797483
- Testing
- Test Fat Blue, Test Fat Green, Test Fat Red
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Outcome Measurement, Physiotherapy and Rehabilitation
Use of Measurement Instruments by Physiotherapists
Measurement instruments in physiotherapy practice play a fundamental role in clinical decision-making, treatment planning, and the objective monitoring of treatment effectiveness.
- Trial name
- NCT07899580
- Testing
- Google Form Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Dental Implantation, Postoperative Pain
Patient-reported Outcome Measures Comparing Static Computer-aided Implant Surgery and Conventional Implant Surgery
The aim of this randomized controlled trial was to compare PROMs in patients receiving single tooth replacement in posterior sites by s-CAIS and CIS.
- Conditions
- Dental Implantation, Postoperative Pain, Computer-assisted Surgery, Patient Outcome Assessment
- Trial name
- NCT04950491
- Testing
- Modified Dental Anxiety Score (MDAS) questionnaire, Pain questionnaire, Oral Health-Related Quality of Life (OHRQoL) questionnaire
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy
Metaplasticity Experimental Design and Comparison of Motor Outcome Measure Sensitivity to Change
The overall objective is to validate the methodology of a metaplasticity experimental design by assessing change in motor excitability after administration of priming transcranial direct current stimulation (tDCS) followed by…
- Trial name
- NCT03304262
- Testing
- rTMS
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Neurofibromatosis Type 1
Reliability of Functional Outcome Measures in Neurofibromatosis 1: Test- Retest
To examine the test-retest reliability (how stable the results are when the same participants, whose symptoms have remained stable, are assessed on 2 different occasions, 14 days apart) of the 10 meter walk test, the timed up and…
- Trial name
- NCT05186870
- Testing
- Outcome measures
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Knee Osteoarthritis
Effectiveness of Contemporary Knee Arthroplasty in Working-age Patients
The aim of our study was to assess the effectiveness of contemporary knee arthroplasty in working-age patients (< 65 years) by conducting a prospective cohort study with 2-year follow up.
- Trial name
- NCT03233620
- Testing
- Knee arthroplasty
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Coxa, Hospital for Joint Replacement
Patient Reported Outcome Measures, Recovery of Function
FIT Study (Functional Outcomes In Trauma Study)
Why? There is not much information in the UK on how well patients who sustain major trauma function afterwards. Major trauma is defined as significant injuries with a calculated 'injury severity score' (ISS) over 15.
- Conditions
- Patient Reported Outcome Measures, Recovery of Function, Rehabilitation, Disability Evaluation
- Trial name
- NCT04074382
- Testing
- Online Questionnaires, Qualitative Interviews
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Sarcopenia
Measurement of Sarcopenia at Post-stroke Rehabilitation Outcome
The purposes of this study are 1. To explore effect of sarcopenia on recovery of post stroke hemiplegia 2. To explore the effect of stroke on sarcopenia and relationship between the degree of sarcopenia and respiration and…
- Trial name
- NCT02793362
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bucheon St. Mary's Hospital