Clinical trials: Outcomes, open to volunteers
Postpartum Hemorrhage, Treatment Outcome
Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum Hemorrhage
This study will investigate all women treated with vacuum-induced tamponade (VIT) for PPH at a tertiary center, namely at the University Hospital Zurich (USZ), over a nine-year period (2017-2025).
- Conditions
- Postpartum Hemorrhage, Treatment Outcome, Pregnancy Outcome
- Trial name
- LOVIT (NCT07885072)
- Where
- Switzerland
- Volunteers
- 380 people
- Sponsor
- University of Zurich
Cognitive Recovery After Stroke, Cognitive Outcome After Stroke
Long-Term Cognitive Recovery After Arteria Cerebri Media Ischemia: A Digital Assessment Using the TuCAN-App
TuCAN-Media is a longitudinal study investigating cognitive recovery after stroke in severely affected patients (modified Rankin Scale [mRS] score ≥ 3) with large vessel occlusion of the arteria cerebri media/middle cerebral…
- Trial name
- TuCAN-Media (NCT07885189)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Tuebingen
Weight Stigma, Pregnancy Outcomes
EMBodied psychOsocial Impacts of Weight Stigma During Pregnancy (EMBODY): A Prospective Cohort Study
The goal of this prospective cohort study is to investigate the contribution of stigma and discrimination due to body size to adverse pregnancy outcomes.
- Conditions
- Weight Stigma, Pregnancy Outcomes, Overweight and Obesity
- Trial name
- EMBODY (NCT06531694)
- Where
- 2 sites in Australia
- Volunteers
- 800 people
- Sponsor
- Monash University
Patient Outcomes
Program in Oncology for Tribal Health Systems.
This clinical trial aims to develop and implement more navigation assistance programs tailored specifically for Native American cancer patients, addressing the current lack of available support.
- Trial name
- NCT07217574
- Testing
- C3PO
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Oklahoma
Patient-Reported Outcome Measures (PROMs), Pragmatic Trial
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study
The goal of this pragmatic clinical trial is to learn if the WE BEAT program, a 5-week group-based online wellbeing and skill-building program, can help teens with congenital heart disease (CHD) improve their ability to handle…
- Conditions
- Patient-Reported Outcome Measures (PROMs), Pragmatic Trial, Adolescent Congenital Heart Disease, Resiliency-building Intervention
- Trial name
- PHN WBC (NCT07525843)
- Testing
- Telemedicine-based resiliency-building intervention
- Where
- 14 sites in United States
- Volunteers
- 390 people
- Sponsor
- Carelon Research
Recovery Outcomes
Quality of Recovery After Colorectal Surgery (Robots vs Laparoscopic)
Minimally invasive techniques for colorectal surgery include standard laparoscopy and robot-assisted laparoscopy. Studies evaluating recovery after anaesthesia and surgery have focused primarily on physiological endpoints…
- Trial name
- NCT07875829
- Testing
- Robotic vs laparoscopic surgery
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- Hospital Central do Funchal
Postoperative Outcomes, Postoperative Complications
The Effect of Perioperative Nutritional Care on Recovery After Knee and Hip Replacement Surgery
This prospective observational study will assess the impact of standardized perioperative nutritional care on postoperative outcomes in patients undergoing elective total hip (THA) or knee arthroplasty (TKA) at the First…
- Conditions
- Postoperative Outcomes, Postoperative Complications, Length of Hospital Stay
- Trial name
- NCT06989229
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Dental Implant, Implant Therapy
Do Immediate Digital Workflows Increase Patient Value?
This two-center randomized controlled trial will evaluate whether an immediate digital posterior implant workflow provides greater patient-defined value than a delayed digital workflow in adults requiring single posterior implant…
- Conditions
- Dental Implant, Implant Therapy, Immediate Dental Implant Placement, Delayed Implant
- Trial name
- ITI PROM RCT (NCT07656597)
- Testing
- Immediate digital posterior implant workflow, Delayed digital posterior implant workflow
- Where
- 2 sites in Germany, Hong Kong
- Volunteers
- 50 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gingivitis, Dental Health
CHEER Oral Health in Pregnancy Study
Many pregnant people don't get the dental care they need, even though it's safe and important. The CHEER Study offers free dental check-ups, cleanings, and supplies to help participants take care of their teeth and gums during…
- Conditions
- Gingivitis, Dental Health, Pregnancy, Pregnancy Outcomes
- Trial name
- CHEER (NCT07377344)
- Testing
- Enhanced Care, Enhanced Care +
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of California, San Francisco
Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs)
Impact of Pharmacotherapy Optimization in Polymedicated Lebanese Older Adults in Primary Health Care Centers
Why are the researchers doing this study? Many older adults take five or more medicines every day. Some of these medicines may no longer help them. Some may even cause harm, such as falls, confusion or tiredness.
- Conditions
- Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs), Primary Health Care, Social Determinants of Health (SDOH)
- Trial name
- PHARMACT-PHC (NCT07866677)
- Testing
- Structured pharmacotherapy optimization, Usual Care
- Where
- Lebanon
- Volunteers
- 452 people
- Sponsor
- National Institute of Public Health, Clinical Epidemiology, and Toxicology-Lebanon (INSPECT-LB)
IVF Outcomes, Prediction Models
Machine-Learning Prediction of Pregnancy Outcomes After Assisted Reproductive Treatments
The goal of this observational study is to develop and validate a machine-learning model to predict pregnancy outcomes in women with a positive pregnancy test following assisted reproductive treatment (ART), with the primary…
- Conditions
- IVF Outcomes, Prediction Models, Infertility Assisted Reproductive Technology, Live Birth
- Trial name
- NCT07855783
- Testing
- Machine-Learning Model for Prediction of Pregnancy Outcomes
- Where
- 2 sites in Croatia
- Volunteers
- 2,200 people
- Sponsor
- BetaPlus Center for Reproductive Medicine
Sepsis, Long Term Care
Long-Term Recovery and Quality of Life in Sepsis Survivors
The goal of this observational study is to learn about the long-term outcomes and recovery of adult patients admitted to the intensive care unit (ICU) with sepsis.
- Conditions
- Sepsis, Long Term Care, Sepsis Scores, Long Term Follow-Up
- Trial name
- UNCOVER (NCT07863128)
- Testing
- Care for Sepsis
- Where
- Switzerland
- Volunteers
- 530 people
- Sponsor
- University of Geneva, Switzerland
Punctate White Matter Lesions, Neurodevelopmental Outcomes
MRI-Based Neurodevelopmental Risk Stratification in Infants With White Matter Injury
The goal of this observational study is to develop and evaluate an MRI-based assessment system for predicting neurodevelopmental outcomes in infants with punctate white matter lesions (PWML).
- Conditions
- Punctate White Matter Lesions, Neurodevelopmental Outcomes, Preterm Infants
- Trial name
- NCT07860749
- Where
- 10 sites in China
- Volunteers
- 260 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Prospective Study , Questionaires, Outcomes
Prospective Study To Assess The Outcomes Of Nitrous Oxide Cryoablation For Treatment Of Duodenal Adenomas In Patients With Hereditary Conditions Such As FAP, HNPCC
To learn how well nitrous oxide cryoballoon ablation, a procedure that uses extreme cold to destroy abnormal tissue, works in treating flat duodenal adenomas (abnormal growths in the small intestine) in people with FAP or Lynch…
- Conditions
- Prospective Study , Questionaires, Outcomes, Nitrous Oxide, Cryoablation
- Trial name
- NCT07859514
- Testing
- Esophagogastroduodenoscopy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Maternal Complications, Pregnancy Complication
Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy
The purpose of this study is to evaluate pregnancy-related health outcomes in participants who are exposed to Epidiolex/Epidyolex during pregnancy and their infant up to 12 months of life.
- Conditions
- Maternal Complications, Pregnancy Complication, Birth Outcomes, Adverse, Pregnancy
- Trial name
- NCT06113237
- Testing
- Epidiolex
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 50 people
- Sponsor
- Jazz Pharmaceuticals
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Weight Management, Health Outcomes
Weight Management and Health Outcomes in College Students
The goal of this study is to learn if a weight management program can improve the overall health of college students. The main questions it aims to answer are: Can a weight management program help college students improve their…
- Conditions
- Weight Management, Health Outcomes, Cardiometabolic Health
- Trial name
- NCT07837999
- Testing
- Weight Management
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Cardiovascular Outcome, Overweight and Obese Women
Impact of Lean Pork on Endothelial Function in Perimenopause
The goal of this study is to examine the impact of a diet high in fresh lean pork, compared to a plant-based diet, on cardiovascular function and vasomotor symptoms in perimenopausal women with overweight and obesity.
- Conditions
- Cardiovascular Outcome, Overweight and Obese Women, Perimenopausal Women, Vasomotor Symptoms (VMS)
- Trial name
- LEAP (NCT06976112)
- Testing
- Pork Diet, Plant Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
ePRO, Symptom Monitoring
Impact of Routine Electronic Patient-Reported Outcome (ePRO)Symptom Monitoring During Neoadjuvant Therapy in Patients withPancreatic Adenocarcinoma on Patient Experience and ClinicalOutcomes: A Prospective Pre-Post Implementation Study
To learn if routine symptom monitoring using questionnaires during chemotherapy and/or radiation therapy in patients with PDAC improves patient health-related quality of life and experience with care.
- Conditions
- ePRO, Symptom Monitoring, Neoadjuvant Therapy, Pancreatic Adenocarcinoma
- Trial name
- NCT07829471
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center