Clinical trials: Outpatient
Knee Arthroscopy
Chloroprocaine Spinal for Outpatient Knee Surgery
Outpatient knee surgeries with duration of less than one hour pose a challenge to the use of spinal anesthesia given that traditional agents remain in effect for 2-3 hours, thus creating a mismatch between length of surgery and…
- Trial name
- NCT03365752
- Testing
- Chloroprocaine, Mepivacaine, General Anesthetics
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Hospital for Special Surgery, New York
Fractures, Bone, Deformity; Bone
Virtual Reality Distraction During Outpatient Pediatric Orthopedic Procedures
Virtual Reality(VR) has had promising applications in science and medicine, including intervention delivery. The use of VR interventions has been studied in a wide range of medical conditions, including anxiety, phobias, obesity…
- Trial name
- NCT05510232
- Testing
- A treatment group that will watch a non-VR video via an iPad, A treatment group that will have headset on and will watch a non-VR video, A treatment group that will be immersed in the VR game (Bear Blast) via the headset.
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Hospital for Special Surgery, New York
Major Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) in the Treatment of Major Depressive Disorder
The primary purpose of this study is to compare the antidepressant efficacy and safety of two doses of DVS SR (25 and 50 mg/day) in the treatment of adults with Major Depressive Disorder.
- Trial name
- NCT00798707
- Testing
- Desvenlafaxine Succinate Sustained-Release (DVS SR)
- Where
- 78 sites in United States, Japan
- Volunteers
- 709 people
- Sponsor
- Pfizer
Drug Use, Opioid-use Disorder
Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections
This study will assess the efficacy of an integrated outpatient treatment model for persons with opioid use disorder and injection related infections.
- Trial name
- BOPAT (NCT04677114)
- Testing
- Buprenorphine and Outpatient Parenteral Antibiotic Therapy, Buprenorphine and standard of care antibiotic treatment
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Laura Fanucchi
Major Depressive Disorder (MDD)
Genomics Used to Improve DEpression Decisions
Evaluate the impact of GeneSight Psychotropic on response to psychotropic treatment as judged by the mean change in the 17-item Hamilton Depression (HAM-D17) score from baseline to end of Week 8 of the study.
- Trial name
- GUIDED (NCT02109939)
- Testing
- GeneSight Psychotropic
- Where
- 61 sites in United States
- Volunteers
- 1,398 people
- Sponsor
- Assurex Health Inc.
Suicide
Zero Suicide Implementation in Outpatient Mental Health Clinics
The aim of this study is to develop a manualized suicide prevention intervention to improve the retention and engagement of suicidal clients.
- Trial name
- NCT05587530
- Testing
- Treatment engagement and retention intervention for suicidal clients
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Columbia University
Post Operative Pain, Nausea
Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery
The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects.
- Trial name
- NCT01149616
- Testing
- Dexamethasone 8mg iv x1
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Sleep Initiation and Maintenance Disorders, Mental Disorders
Twenty-six Week Extension Trial of Org 50081 (Esmirtazapine) in Outpatients With Chronic Primary Insomnia (176003/P05721/MK-8265-007)
This trial is a 26-week, open label extension trial to investigate safety and explore efficacy of esmertazapine in participants with insomnia who completed protocol 21106/P05701/MK-8265-002 (NCT00631657).
- Conditions
- Sleep Initiation and Maintenance Disorders, Mental Disorders, Dyssomnias, Sleep Disorders
- Trial name
- NCT00750919
- Testing
- esmirtazapine
- Volunteers
- 184 people
- Sponsor
- Merck Sharp & Dohme LLC
Cannabis-use Disorders
Behavioral Effects of Pregabalin and Cannabis
Cannabis is the most commonly used illicit drug in the United States, and its use is associated with rates of development of abuse and dependence, treatment admission and relapse that are comparable to other illicit drugs.
- Trial name
- NCT01511640
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joshua A. Lile, Ph.D.
Depression, Adolescent - Emotional Problem
Light Therapy for Depression in Adolescent Outpatients
The goal of this placebo lead-in clinical trial was to test bright light therapy (BLT) in adolescents with depression. The main question[s] it aimed to answer were: 1.
- Trial name
- NCT05823090
- Testing
- light box (Carex DayLight Classic Model)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Lymphoma, Non-Hodgkin, Lymphoma
A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-007)
This is an open-label, multicenter, Phase 2 study to determine the safety, PK, and efficacy of lisocabtagene maraleucel (JCAR017) in subjects who have relapsed from, or are refractory to, two lines of immunochemotherapy for…
- Conditions
- Lymphoma, Non-Hodgkin, Lymphoma, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse
- Trial name
- NCT03744676
- Testing
- lisocabtagene maraleucel
- Where
- 23 sites in United States
- Volunteers
- 104 people
- Sponsor
- Juno Therapeutics, a Subsidiary of Celgene
Acute Pain, Hysteroscopy
Virtual Reality and Outpatient Hysteroscopy
TITLE Virtual Reality (VR) as a Distraction technique for management of acute pain at Outpatient Hysteroscopy DESIGN Randomised Control Trial (RCT) with Mixed methods - Qualitative and quantitative AIMS To study the role of…
- Trial name
- VISTA (NCT03699280)
- Testing
- Virtual Reality
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Sleep Initiation and Maintenance Disorders
Safety and Efficacy Study of Ramelteon in Subjects With Chronic Insomnia
The purpose of this study is to determine the safety and efficacy of 4 mg of Ramelteon, once daily (QD), in subjects with chronic insomnia.
- Trial name
- NCT00756002
- Testing
- Ramelteon
- Volunteers
- 259 people
- Sponsor
- Takeda
Major Depressive Disorder
A 6-Month Extension Study To The B2061032 Study To Evaluate The Safety, Tolerability, And Efficacy Of DVS SR In The Treatment Of Child And Adolescent Outpatients With MDD
This is a 6-month, open-label, flexible-dose study evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) in the Treatment of Child and Adolescent Outpatients with Major Depressive Disorder (MDD).
- Trial name
- NCT01371708
- Testing
- DVS SR
- Where
- 36 sites in United States, Chile
- Volunteers
- 283 people
- Sponsor
- Pfizer
Malignant Tumor of Ill-defined Site
LCI-NOS-PAIN-001: A Prospective, Pharmacogenomic-Driven Study of Pain Management in Oncology Outpatients
About half of all cancer patients seen in oncology clinics have pain at initial assessment; pain relief within a one-month period is seen in approximately one third of these patients and pain worsening in about one fifth.
- Trial name
- NCT02542397
- Testing
- Pharmacogenomic Testing
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes Mellitus Type 1
A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic Pancreas
This study will test the hypothesis that a wearable bionic pancreas system that automatically delivers insulin and glucagon can provide superior regulation of glycemia versus usual care for adults with type 1 diabetes.
- Trial name
- NCT02092220
- Testing
- Bionic Pancreas, Insulin pump with or without CGM
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- Massachusetts General Hospital
Covid19
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm B (Fluvoxamine)
The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19.
- Trial name
- NCT05890586
- Testing
- Fluvoxamine
- Where
- 91 sites in United States
- Volunteers
- 1,331 people
- Sponsor
- Susanna Naggie, MD
Type 1 Diabetes
The International Diabetes Closed Loop (iDCL) Trial: Protocol 4
The investigators aim to compare the efficacy and safety of an AID system using an adaptive MPC algorithm versus SAP (which may or may not include PLGS; to be referred to as SAP) in people with type 1 diabetes.
- Trial name
- DCLP4 (NCT04436796)
- Testing
- interoperable Artificial Pancreas System (iAPS), Sensor-Augmented Pump (SAP)/Predictive Low Glucose Suspend (PLGS)
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Sansum Diabetes Research Institute
COVID-19
COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection
The primary objective of the study is to assess the virologic efficacy of REGN10933+REGN10987 across different intravenous and subcutaneous doses compared to placebo.
- Trial name
- NCT04666441
- Testing
- REGN10933+REGN10987 combination therapy
- Where
- 57 sites in United States
- Volunteers
- 1,149 people
- Sponsor
- Regeneron Pharmaceuticals
Pain
Lidocaine and Outpatient Gynecologic Laparoscopy
Although ambulatory gynecological laparoscopy is considered to be a minimally invasive surgical procedure, only 60% of patients undergoing this procedure are satisfied with postoperative pain control.
- Trial name
- NCT01250002
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University