Clinical trials: Ovarian Endometriosis
Endometriosis, Ovarian
MRI-Based Prediction of Dienogest Response in Endometriosis
The goal of this prospective observational study is to learn whether magnetic resonance imaging (MRI) findings can help predict treatment response to dienogest in women with endometriosis.
- Trial name
- ESMRIDNG (NCT07446608)
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Chungnam National University Sejong Hospital
Ovarian Endometrioma
Randomized Study on Endometrioma Treatment
This is a randomised study comparing the effect of two laparoscopic techniques for treatment of ovarian endometriomas on recurrence rate and ovarian reserve.
- Trial name
- NCT00989118
- Testing
- Laser treatment of ovarian endometrioma
- Where
- Spain
- Sponsor
- Hospital Clinic of Barcelona
Ovarian Endometrioma, Endometriosis
Guangdong Endometriosis Retrospective Clinical Cohort
This retrospective cohort study evaluates the association between postoperative hormonal treatment and recurrence of ovarian endometriosis in women undergoing surgery for ovarian endometrioma.
- Trial name
- NCT07519213
- Where
- China
- Volunteers
- 1,121 people
- Sponsor
- Guangdong Women and Children Hospital
Endometriosis, Endometriosis Ovary
Safety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the Endometriosis
Background: Endometriosis is a chronic gynecological disease with the growth of endometrial tissue outside the endometrium. In all its properties, this tissue is similar to the mucous membrane of the uterus.
- Conditions
- Endometriosis, Endometriosis Ovary, Endometriosis Externa, Endometriosis, Rectum
- Trial name
- ELTA (NCT03481842)
- Testing
- Linifanib, BIBW2992, Axitinib
- Where
- Switzerland
- Sponsor
- BioGene Pharmaceutical Ltd.
Endometriosis Ovary
Deep Infiltrating Endometriosis : Laparoscopic Nerve-sparing Surgery and Use of Neutral Argon Plasma
Medical treatment of endometriosis has a suspensive and sometimes incomplete effect on the symptoms, making surgical treatment necessary.
- Trial name
- DIE (NCT06207448)
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Strasbourg, France
Endometriosis, Dermoid Cyst
Oocyte Freezing for Fertility Preservation in Benign Ovarian Tumors
Benign ovarian cysts are frequent during women's life. They are diagnosed with pelvic pain or fortuitously during an ultra-sonographic exam.
- Conditions
- Endometriosis, Dermoid Cyst, Mucinous Cyst
- Trial name
- OFBOT (NCT03823833)
- Where
- France
- Volunteers
- 82 people
- Sponsor
- University Hospital, Lille
Endometrioma, Endometriosis Ovary
The Therapy of Large Endometrioma
Endometrioma's prevalence is between 23 and 55%. It causes pelvic pain, decrease fertility and ovarian reserve. Currently, there's no recommendation about large endometrioma's treatment and there's no information on the best…
- Trial name
- ENDOKYSTE (NCT04704115)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Lille
Endometriosis, Endometriosis Ovary
Pretreatment With Dienogest in Women With Endometriosis Undergoing in Vitro-fertilization After a Previous Failed Cycle
It is generally assumed that the major causes of in vitro fertilization (IVF) failure in women with endometriosis are diminished ovarian reserve, impaired endometrial receptivity and low quality of embryos.
- Conditions
- Endometriosis, Endometriosis Ovary, IVF
- Trial name
- NCT04306276
- Testing
- Dienogest 2 MG
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Ospedale Policlinico San Martino
Endometriosis
The Impact of Surgical Treatment of Endometriomas on Ovarian Reserve
The aim of this study is to assess which of two commonly used surgical procedures in the treatment of ovarian cysts called endometriomas (cutting out of the cyst - "cystectomy", or draining it and cauterising it's inner lining …
- Trial name
- NCT01425333
- Testing
- Surgery for ovarian endometrioma
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Saad Amer
Ovarian Cysts, Endometriosis
Evaluation of Adhexil Safety and Efficacy in Prevention and/or Reduction of Adhesions in Gynecological Surgery
The objective of this study is to evaluate the safety and efficacy of ADHEXIL™ in preventing and/or reducing post-operative adhesions in patients undergoing surgery involving the ovaries.
- Conditions
- Ovarian Cysts, Endometriosis, Adhesions
- Trial name
- NCT00865488
- Testing
- ADHEXIL
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 80 people
- Sponsor
- OMRIX Biopharmaceuticals
Benign Ovarian Cyst
Comparison of Hemostatic Agent to Suture in Terms of Hemostatic Function and Preservation of Ovarian Function
This study aims to evaluate the efficacy of preservation of ovarian function, hemostasis, and safety of a hemostatic agent versus suturing during laparoscopic ovarian cystectomy for ovarian endometriosis.
- Trial name
- PRAHA-2 (NCT04643106)
- Testing
- Hemostatic agent (EVICEL®) application during laparoscopic ovarian cystectomy, suturing with barbed sutures during laparoscopic ovarian cystectomy
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Indocyanine Green (ICG), Robotic Surgical Procedure
Assessing the Efficacy of Indocyanine Green for Ureter Identification During Robot-Assisted Surgery in Advanced-Stage Endometriosis
The goal of this side-randomized, self-controlled trial, 1-site study is to explore the efficacy of Indocyanine Green Fluorescence (ICG) for Intraoperative Ureter Identification During Robot-Assisted Single-Site Surgery in…
- Conditions
- Indocyanine Green (ICG), Robotic Surgical Procedure, Deep Infiltrating Endometriosis (DIE), Endometriosis Pelvic
- Trial name
- NCT07144904
- Testing
- Indocyanine Green (ICG)-Assisted Ureteral Identification, Standard Ureteral Identification without ICG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Endometriosis, Ovarian
Edessy Stem Cell Score (ESS), Endometrium, Endometrioma
Purpose of this study is to evaluate stem cell expression (SCE) in endometriotic (E) and non endometriotic ovarian and endometrial tissues.
- Trial name
- NCT02103452
- Testing
- Ovarian and endometrial samples
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Endometrioma
Comparison of Laparoscopic Endometrioma Stripping Versus Ethanol Sclerotherapy( CLESS)
The aim of this study is to compare two different laparoscopic surgical techniques (endometrioma stripping vs ethanol sclerotherapy) in terms of ovarian reserve (AMH levels), recurrence rate and pain relief.
- Trial name
- CLESS (NCT04178876)
- Testing
- ethanol sclerotherapy, stripping technique
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Catholic University of the Sacred Heart
Ovarian Reserve
Effects of Dienogest and Dienogest Plus Estradiol Valerate in Ovarian Endometrioma
Progesterone resistance in endometriosis is a known fact. The progestin derivatives used in endometriosis cause decidualization and atrophy of ectopic foci.
- Trial name
- NCT03789123
- Testing
- Estradiol valerate/dienogest
- Where
- Turkey (Türkiye)
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Endometriosis
Ovarian Blockade During Fertility Preservation in Patients With Endometriosis
The aim of the study is to demonstrate the non-inferiority of dienogest on the number of mature oocytes collected compared with "conventional" ovarian stimulation protocols (using a GnRH agonist or antagonist), in patients with…
- Trial name
- PFENDO (NCT06106919)
- Testing
- surveys (Fertiqol and WHOQOL-BREF)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Endometriosis
PGL5001 Proof of Concept Study in Inflammatory Endometriosis
This is a prospective, three-part (Part A1, Part A2 and Part B),Phase II study investigating the efficacy, safety, pharmacokinetics and pharmacodynamics of the JNK inhibitor PGL5001 orally administered for up to 5 months with…
- Trial name
- JADE (NCT01630252)
- Testing
- PGL5001
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- PregLem SA
Endometriosis Ovary
Impact on Ovarian Reserve According to the Type of Ovarian Endometrioma Excision: Laser Versus Conventional Cystectomy
Endometriosis is a disease characterized by the presence of endometrial tissue outside the uterus cavity, causing important chronic pain and sterility in those patients suffering from it.
- Trial name
- NCT03826355
- Testing
- CO2 (carbon dioxide) laser vaporisation, Stripping technique
- Volunteers
- 16 people
- Sponsor
- Hospital Clinic of Barcelona
Ovarian Endometrioma, Endometriosis
Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas
The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas.
- Trial name
- ENDO-ARGON (NCT07711743)
- Testing
- Argon Plasma Coagulation
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Endometrioma, Endometriosis
Second Laparoscopic Surgery for Recurrent Unilateral Endometriomas.
This retrospective case-control study was performed in an Academic centre for the diagnosis and treatment of endometriosis. It included patients with recurrent unilateral endometriomas who were previously operated for the same…
- Conditions
- Endometrioma, Endometriosis, Surgery
- Trial name
- NCT02047838
- Testing
- Anti-mullerian hormone (AMH) level dosage., Follicle-stimulating hormone (FSH) level dosage., Antral follicle count (AFC).
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy