Clinical trials: Ovarian Hyperstimulation
Ovarian Hyperstimulation
Progesterone Diurnal Rhythm During Ovarian Stimulation for IVF
To evaluate the influence of circadian rhythm on progesterone levels during follicular phase of natural cycle and during follicular phase of controlled ovarian stimulation during IVF.
- Trial name
- NCT02975713
- Where
- United Arab Emirates
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Ovarian Stimulation in ICSI
Controlled Ovarian Hyperstimulation (COH) With Sequential HPFSH & HMG Versus Rec-F.S.H Alone in ICSI Cycle
despite the large number of papers published on COH protocols comparing the efficiency of different exogenous gonadotropins, no confirmed protocol exists, and it is not quite clear which is superior to the others.
- Trial name
- NCT04539613
- Testing
- HPFSH & HMG
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alaa Fouli Gaber Ebrahim
Oocyte Donation
Immunogenicity of Repeated Follicle Stimulating Hormone (FSH) Stimulation Cycles
The purpose of the study is to evaluate immunogenic potential of FSH-IBSA in healthy volunteers undergoing controlled ovarian hyperstimulation (COH) in an oocyte donation program.
- Trial name
- NCT01785095
- Testing
- FSH (Follicle Stimulating Hormone)
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- IBSA Institut Biochimique SA
Infertility
Luteal Phase Progesterone in IUI and Gonadotropin Cycles
This is a study of patients undergoing Controlled Ovarian Hyperstimulation (COH) with Gonadotropins and Intrauterine Insemination (IUI) at a Fertility Clinic.
- Trial name
- NCT01941875
- Testing
- Progesterone Effervescent Vaginal Tablets
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Ovarian Hyperstimulation Syndrome
Study of Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in In Vito Fertilization Cycles and Derivation of OHSS Biomarkers
The purpose of this study is to determine whether cabergoline is effective in reducing the incidence and severity of Ovarian Hyperstimulation Syndrome (OHSS), especially for severe cases; and to derive biomarkers for the risk of…
- Trial name
- NCT01535859
- Testing
- Cabergoline
- Where
- Singapore
- Volunteers
- 46 people
- Sponsor
- KK Women's and Children's Hospital
Ovarian Hyperstimulation Syndrome, Infertility, Female
Dual Trigger" in IVF Patients at High Risk of Ovarian Hyper Stimulation Syndrome
The present study aims to evaluate whether the use of a "dual trigger" can improve IVF outcomes, compared to GnRH agonist (GnRH-a) alone, in patients at high risk of OHSS undergoing a freeze-all cycle.
- Trial name
- NCT05638529
- Testing
- Pregnyl (1,500) IU, 1.5 mL of normal saline
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Mount Sinai Hospital, Canada
Infertility
Prospective, Randomized, Controlled, Clinical Study on Tolerability and Efficacy of hMG-IBSA
Purpose of the study is the evaluation of the tolerability (both local and systemic) and the clinical efficacy (in terms oocytes recovered) of subcutaneously versus intramuscularly administered Merional® (IBSA, Lugano - CH) in…
- Trial name
- NCT00464607
- Testing
- hMG-IBSA, Ovarian stimulation
- Where
- 4 sites in Italy
- Volunteers
- 160 people
- Sponsor
- IBSA Institut Biochimique SA
Infertility and at High Risk of OHSS
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022241
- Testing
- triptorelin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chenshiling
Controlled Ovarian Hyperstimulation, Polycystic Ovarian Syndrome
Progesterone Primed Ovarian Stimulation Versus GnRH Antagonist Protocols in Women With Polycystic Ovarian Syndrome
The purpose of this study is to compare the use of the progesterone-primed ovarian stimulation protocol versus GnRH antagonist protocol in women with polycystic ovarian syndrome (PCOS) regarding the number of oocytes retrieved…
- Trial name
- NCT06812559
- Testing
- Progesterone, GnRH antagonist (Cetrorelix)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- El Shatby University Hospital for Obstetrics and Gynecology
Ovarian Hyperstimulation Syndrome
Coasting Versus Antagonist Protocol in Patients at High Risk of OHSS
The aim of this work is to study the value of GnRH antagonist subcutaneous administration as an alternative to coasting in prevention of severe OHSS and its impact on embryos quality \& the outcome of ICSI.
- Trial name
- NCT03996434
- Testing
- Gonadotropin, Antagonist
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- ClinAmygate
Infertility, Controlled Ovarian Hyperstimulation
Follicular Steroid Genesis in Controlled Ovarian Stimulation
Serum concentrations of the different hormones involved in follicular steroid genesis during a cycle of controlled ovarian stimulation with recombinant FSH or HMG will be compared in this study.
- Trial name
- ESTEFOL (NCT02738580)
- Testing
- COS with GnRH antagonists and rFSH, COS with GnRH antagonists and HP-HMG
- Where
- Spain
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
In Vitro Fertilization
A Study of the Effects of a Novel Ovarian Stimulation Regimen on Embryo Aneuploidy Rates in In Vitro Fertilization (IVF)
Background: By limiting the number of embryos transferred to the uterus to only a single embryo, the risk of multiple gestation can be reduced.
- Trial name
- NCT00866008
- Testing
- Ovarian stimulation
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bart CJM Fauser
Aneuploidy
Aneuploidies and Different Stimulation Protocols
Our working hypothesis is that patients undergoing "in vitro" fertilization (IVF) with higher response to ovarian stimulation protocols recover a higher number of oocytes and, this elevated response could be translated into…
- Trial name
- NCT00802295
- Testing
- Gonadotrophins, Low dosis Gonadotrophin
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Female Infertility Due to Nonimplantation of Ovum, Complications Associated With Artificial Fertilization
Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
The purpose of this study is to assess the non-inferiority of a multidose GnRH antagonist (cetrorelix) regimen to a GnRH agonist (triptorelin) long protocol in young infertile women undergoing ovarian stimulation with Pergoveris…
- Trial name
- Pergoveris (NCT01565265)
- Testing
- Pergoveris in long protocol with GnRH agonist, Pergoveris in GnRH antagonist protocol
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Infertility
Calcium Dobesilate Versus Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome
The purpose of this study is to compare the effect of oral Calcium Dobesilate to oral Cabergoline in the prevention of ovarian hyperstimulation syndrome (OHSS) in high-risk women underwent intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT02271360
- Testing
- Calcium Dobesilate, Cabergoline
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
Ovarian Hyperstimulation Syndrome
The Role of Cetrotide Acetate in Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in Oocyte Donors
This pilot study aims to address whether the prophylactic use of Cetrorelix Acetate after a long gonadotropin-releasing hormone (GnRH) agonist protocol post-hCG (human chorionic gonadotropin) administration can significantly…
- Trial name
- NCT00867659
- Testing
- Cetrotide acetate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Center for Reproductive Medicine
OHSS
Cabergoline and Coasting to Prevent OHSS
The effectiveness of cabergoline to prevent moderate-severe OHSS to coasting.
- Trial name
- OHSS (NCT01984320)
- Testing
- ICSI
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Ovarian Hyperstimulation Syndrome (OHSS)
Controlled Ovarian Stimulation by HP-hMG for IVF / ICSI Cycles: Study on Ovarian Hyper Stimulation Syndrome in a Cohort of Women From 18 to 36 Years Old.
Ovarian hyper stimulation syndrome (OHSS) is a potentially serious complication of ovarian stimulation in IVF (In Vitro Fertilisation).
- Trial name
- SHOview (NCT01703728)
- Testing
- Highly purified menotropin (HP- hMG) treatment
- Where
- 20 sites in France
- Volunteers
- 455 people
- Sponsor
- Ferring Pharmaceuticals
Endometriosis, Ovarian Cysts
Danazol Treatment in Endometriosis Women Before IVF
The purpose of this study is to determine whether pre-treatment with danazol for at least 4 months before controlled ovarian hyperstimulation for IVF cycles improves pregnancy rate.
- Conditions
- Endometriosis, Ovarian Cysts, Infertility
- Trial name
- NCT01779232
- Testing
- Danazol
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Ovarian Hyper Stimulation Syndrome (OHSS)
Ovarian Hyperstimulation Syndrome Prevention
Ovarian hyperstimulation is a very hazardous complication of ICSI
- Trial name
- OHSS (NCT06739759)
- Testing
- Antagonist protocol for IVF, Modified Agonist protocol for IVF with additive treatments as HCQ
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Aljazeera Hospital